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Outputs (18)

Rationale and design of ELIXIR, a randomized, controlled trial to evaluate efficacy and safety of XyloCore, a glucose-sparing solution for peritoneal dialysis. (2024)
Journal Article
Bonomini, M., Davies, S., Kleophas, W., Lambie, M., Reboldi, G., Liberato, L. D., Divino-Filho, J. C., Heimburger, O., Ortiz, A., Povlsen, J., Iacobelli, M., Prosdocimi, T., & Arduini, A. (2024). Rationale and design of ELIXIR, a randomized, controlled trial to evaluate efficacy and safety of XyloCore, a glucose-sparing solution for peritoneal dialysis. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608241274106

Peritoneal dialysis adoption and technique survival is affected by limitations related to peritoneal membrane longevity and metabolic alterations. Indeed, almost all peritoneal dialysis fluids exploit glucose as an osmotic agent that rapidly diffuses... Read More about Rationale and design of ELIXIR, a randomized, controlled trial to evaluate efficacy and safety of XyloCore, a glucose-sparing solution for peritoneal dialysis..

Impact of Chronic Kidney Disease on the Processes of Care and Long-Term Mortality of Non-ST-Segment-Elevation Myocardial Infarction: A Nationwide Cohort Study and Long-Term Follow-Up. (2024)
Journal Article
Weight, N., Moledina, S., Ullah, M., Wijeysundera, H. C., Davies, S., Chew, N. W. S., Lawson, C., Khan, S. U., Gale, C. P., Rashid, M., & Mamas, M. A. (in press). Impact of Chronic Kidney Disease on the Processes of Care and Long-Term Mortality of Non-ST-Segment-Elevation Myocardial Infarction: A Nationwide Cohort Study and Long-Term Follow-Up. Journal of the American Heart Association, 13(16), Article e032671. https://doi.org/10.1161/JAHA.123.032671

A growing population of patients with chronic kidney disease (CKD) presents with non-ST-segment-elevation myocardial infarction, although little is known about their longer-term mortality. Using the MINAP (Myocardial Ischaemia National Audit Project)... Read More about Impact of Chronic Kidney Disease on the Processes of Care and Long-Term Mortality of Non-ST-Segment-Elevation Myocardial Infarction: A Nationwide Cohort Study and Long-Term Follow-Up..

#1248 Sex specific associations between fat free mass and weight with mortality: sequences of regressions analyses from the UK Biobank cohort (2024)
Presentation / Conference
Tabinor, M., Potts, J., Ferro, C. J., Davies, S., & Solis-Trapala, I. (2024, May). #1248 Sex specific associations between fat free mass and weight with mortality: sequences of regressions analyses from the UK Biobank cohort. Presented at 61st ERA Congress, Stockholm, Sweden

Background and Aims There is growing evidence that muscle mass (MM) loss, observed in long term conditions (LTCs), including chronic kidney disease (CKD), is associated with mortality. This study aimed to explore the direct association between MM and... Read More about #1248 Sex specific associations between fat free mass and weight with mortality: sequences of regressions analyses from the UK Biobank cohort.

#2832 Lean tissue mass is associated with mortality across different stages of chronic kidney disease: a systematic review and meta-analysis (2024)
Presentation / Conference Contribution
Tabinor, M., Elphick, E., Stephens, C., Wall, N., Ul Hussain, A., Shah, R., Peracha, J., Anderson, B., Istanbuly, O., Solis-Trapala, I., Ferro, C. J., & Davies, S. (2024, May). #2832 Lean tissue mass is associated with mortality across different stages of chronic kidney disease: a systematic review and meta-analysis. Presented at 61st ERA Congress, Stockholm, Sweden

Background and Aims Loss of lean tissue mass (LLTM) commonly occurs in multiple long-term conditions (LTC), including chronic kidney disease (CKD), and is thought to be associated with adverse outcomes including mortality, frailty surrogates and poor... Read More about #2832 Lean tissue mass is associated with mortality across different stages of chronic kidney disease: a systematic review and meta-analysis.

#2796 Divergent associations between mortality and different measures of renal function after adjustment for body composition: results from the UK Biobank (2024)
Presentation / Conference
Tabinor, M., Potts, J., Ferro, C. J., Davies, S., & Solis-Trapala, I. (2024, May). #2796 Divergent associations between mortality and different measures of renal function after adjustment for body composition: results from the UK Biobank. Presented at 61st ERA Congress, Stockholm, Sweden

Background and Aims There is data suggesting estimated glomerular filtration rate using Cystatin-C (eGFRCystatin-C) is superior to the creatinine-based (eGFRCreat) method when assessing associations between renal function and mortality (Lees et al. 2... Read More about #2796 Divergent associations between mortality and different measures of renal function after adjustment for body composition: results from the UK Biobank.

Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England (2024)
Journal Article
Damery, S., Lambie, M., Williams, I., Coyle, D., Fotheringham, J., Solis-Trapala, I., Allen, K., Potts, J., Dikomitis, L., & Davies, S. J. (2024). Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608241232200

Background:
Disparities in home dialysis uptake across England suggest inequity and unexplained variation in access. We surveyed staff at all English kidney centres to identify patterns in service organisation/delivery and explore correlations with... Read More about Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England.

The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system. (2024)
Journal Article
Talbot, B., Davies, S., Burman, J., Ritchie, A., Snelling, P., Lynch, S., Park, Y., Jones, B., Garvey, V., Jaure, A., Jardine, M., Perkovic, V., Gallagher, M., Brandwood, A., Kaur, N., & Knight, J. (in press). The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608231209850

The global unmet need for kidney replacement therapy means that millions of people die every year as they cannot afford treatment. Peritoneal dialysis (PD) offers comparable survival to haemodialysis and is often more affordable, but one barrier to i... Read More about The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system..