Outputs (2)

The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins (2016)
Journal Article
Ball, M., Baron, A., Bradshaw, B., Dumeunier, R., O'Brien, M., & Thomas, E. J. The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins. Organic and Biomolecular Chemistry, 14(40), 9650-9681. https://doi.org/10.1039/c6ob01804a

The development of a synthesis of the C1–C16 fragment of bryostatins in which the key step is a stereoselective oxy-Michael reaction used to assemble the cis-2,6-disubstituted tetrahydropyran with the exocyclic alkene already installed, is described.... Read More about The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins.

4.2.1.4. Cram’s Rule – Diastereoselective Grignard Addition to 2-Phenylpropanal (2016)
Book Chapter
Hancock, L. M., Edwards, M. G., Jones, G. R., & O’Brien, M. (2016). 4.2.1.4. Cram’s Rule – Diastereoselective Grignard Addition to 2-Phenylpropanal. In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (319-321). Royal Society of Chemistry. https://doi.org/10.1039/9781849739634-00319