Stereoselectivity and conformational control in the synthesis of ajmaline and epi-ajmaline alkaloids
(2013)
Journal Article
Bailey, P. D., Beard, M. A., Cresswell, M., Dang, H. P., Pathak, R. B., Phillips, T. R., & Price, R. A. (2013). Stereoselectivity and conformational control in the synthesis of ajmaline and epi-ajmaline alkaloids. Tetrahedron Letters, 54(13), 1726-1729. https://doi.org/10.1016/j.tetlet.2013.01.074
Careful choice of the N-protecting group provides crucial conformational control, allowing ring-closure to the indole 3-position in the late stages of the synthesis of ajmaline alkaloids; the choice of protecting group and reducing agent can also pro... Read More about Stereoselectivity and conformational control in the synthesis of ajmaline and epi-ajmaline alkaloids.