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Outputs (2095)

Carrier-free chemo-phototherapeutic nanomedicines with endo/lysosomal escape function enhance the therapeutic effect of drug molecules in tumors (2024)
Journal Article
Feng, X., Brown, C. M., Wang, H., Kashif, S., Roberts, S., Yan, L., …Chen, X. (in press). Carrier-free chemo-phototherapeutic nanomedicines with endo/lysosomal escape function enhance the therapeutic effect of drug molecules in tumors. Journal of Materials Chemistry B, 12(27), 6703-6715. https://doi.org/10.1039/d4tb00465e

Carrier-free nanomedicines offer advantages of extremely high drug loading capacity (>80%), minimal non-drug constituent burden, and facile preparation processes. Numerous studies have proved that multimodal cancer therapy can enhance chemotherapy ef... Read More about Carrier-free chemo-phototherapeutic nanomedicines with endo/lysosomal escape function enhance the therapeutic effect of drug molecules in tumors.

First-principles investigation of the interaction between pentacene molecules and monolayer transition metal dichalcogenides (2024)
Thesis
Black, E. J. First-principles investigation of the interaction between pentacene molecules and monolayer transition metal dichalcogenides. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/1018715

The search for new materials for photonic applications continues to expand, and one promising route is that of van der Waals heterostructures. Assembled layer by layer from atomically thin materials, there are combinations of materials with promising... Read More about First-principles investigation of the interaction between pentacene molecules and monolayer transition metal dichalcogenides.

The fate of massive single stars: exploring the impact of rotation and metallicity (2024)
Thesis
Chambers, C. S. The fate of massive single stars: exploring the impact of rotation and metallicity. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/1018847

The fate of massive stars depends largely on the mass and structure of their inner cores, and the composition of their envelopes at death. This is dependent on the mass loss history of the star, which has significant effects on the evolution of massi... Read More about The fate of massive single stars: exploring the impact of rotation and metallicity.

Towards the synthesis of a 2-deoxy-2-fluoro-d-mannose building block and characterisation of an unusual 2-S-phenyl anomeric pyridinium triflate salt via 1 → 2 S-migration (2024)
Journal Article
Evans, S. T., Tizzard, G. J., Field, R. A., & Miller, G. J. (2024). Towards the synthesis of a 2-deoxy-2-fluoro-d-mannose building block and characterisation of an unusual 2-S-phenyl anomeric pyridinium triflate salt via 1 → 2 S-migration. Carbohydrate Research, 545, Article 109275. https://doi.org/10.1016/j.carres.2024.109275

Regio- and stereo-selective synthetic routes to 2-deoxy-2-fluoro-d-mannose building blocks are often experimentally challenging when using Selectfluor with the corresponding glycal. We targeted a late-stage method to introduce fluorine in a stereospe... Read More about Towards the synthesis of a 2-deoxy-2-fluoro-d-mannose building block and characterisation of an unusual 2-S-phenyl anomeric pyridinium triflate salt via 1 → 2 S-migration.

Processing of GASKAP-Hi pilot survey data using a commercial supercomputer (2024)
Journal Article
Kemp, I., Pingel, N., Worth, R., Wake, J., Mitchell, D., Midgely, S., …van Loon, J. T. (2025). Processing of GASKAP-Hi pilot survey data using a commercial supercomputer. Astronomy and Computing, 51, Article 100901. https://doi.org/10.1016/j.ascom.2024.100901

Modern radio telescopes generate large amounts of data, with the next generation Very Large Array (ngVLA) and the Square Kilometre Array (SKA) expected to feed up to 292 GB of visibilities per second to the science data processor (SDP). However, the... Read More about Processing of GASKAP-Hi pilot survey data using a commercial supercomputer.

A possible misaligned orbit for the young planet AU Mic c (2024)
Journal Article
Yu, H., Garai, Z., Cretignier, M., Szabó, G. M., Aigrain, S., Gandolfi, D., …Wheatley, P. J. (in press). A possible misaligned orbit for the young planet AU Mic c. Monthly Notices of the Royal Astronomical Society, 18. https://doi.org/10.1093/mnras/stae2655

The AU Microscopii planetary system is only 24 Myr old, and its geometry may provide clues about the early dynamical history of planetary systems. Here, we present the first measurement of the Rossiter-McLaughlin effect for the warm sub-Neptune AU Mi... Read More about A possible misaligned orbit for the young planet AU Mic c.

Architecture of TOI-561 planetary system (2024)
Journal Article
Piotto, G., Zingales, T., Borsato, L., Egger, J. A., Correia, A. C. M., Simon, A. E., …Wolf, S. (in press). Architecture of TOI-561 planetary system. Monthly Notices of the Royal Astronomical Society, 535(3), 2763-2774. https://doi.org/10.1093/mnras/stae2440

We present new observations from CHEOPS (CHaracterising ExOPlanet Satellite) and TESS (Transiting Exoplanet Survey Satellite) to clarify the architecture of the planetary system hosted by the old Galactic thick disc star TOI-561. Our global analysis,... Read More about Architecture of TOI-561 planetary system.

Synthesis of Nucleoside Analogs Containing Sulfur or Selenium Replacements of the Ribose Ring Oxygen or Carbon. (2024)
Journal Article
Benckendorff, C. M. M., Sunde-Brown, P., Ní Cheallaigh, A., & Miller, G. J. (2024). Synthesis of Nucleoside Analogs Containing Sulfur or Selenium Replacements of the Ribose Ring Oxygen or Carbon. Journal of Organic Chemistry, 89(23), 16977-16989. https://doi.org/10.1021/acs.joc.4c02409

Nucleoside analogs have proven highly successful in many pharmaceutical intervention strategies, and continued exploration of next generation structural motifs is required. Herein we discuss recent advances toward the chemical synthesis of heteroatom... Read More about Synthesis of Nucleoside Analogs Containing Sulfur or Selenium Replacements of the Ribose Ring Oxygen or Carbon..

An ultra-short-period super-Earth with an extremely high density and an outer companion (2024)
Journal Article
Livingston, J. H., Gandolfi, D., Trani, A. A., Herath, M., Barragán, O., Hatzes, A., …Tamura, M. (in press). An ultra-short-period super-Earth with an extremely high density and an outer companion. Scientific Reports, 14(1), Article 27219. https://doi.org/10.1038/s41598-024-76490-y

We present the discovery and characterization of a new multi-planetary system around the Sun-like star K2-360 (EPIC 201595106). K2-360 was first identified in K2 photometry as the host of an ultra-short-period (USP) planet candidate with a period of... Read More about An ultra-short-period super-Earth with an extremely high density and an outer companion.