A humanised thrombus-on-a-chip model utilising tissue-engineered arterial constructs: A method to reduce and replace mice used in thrombosis and haemostasis research.
(2025)
Journal Article
Ranjbar, J., Gibbins, J. M., M. Gibbins, J., Roe, J., Roach, P., Yang, Y., & Harper, A. G. S. (2025). A humanised thrombus-on-a-chip model utilising tissue-engineered arterial constructs: A method to reduce and replace mice used in thrombosis and haemostasis research. F1000Research, 14, 1-38. https://doi.org/10.12688/f1000research.158910.1
The study of in vivo thrombus formation has principally been performed using intravital microscopy in mice and other species. These have allowed us to visualise the molecular and cellular processes that regulate thrombus formation inside the body. Ho... Read More about A humanised thrombus-on-a-chip model utilising tissue-engineered arterial constructs: A method to reduce and replace mice used in thrombosis and haemostasis research..