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Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord.

Mennan, Claire; Wright, Karina; Bhattacharjee, Atanu; Balain, Birender; Richardson, James; Roberts, Sally

Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord. Thumbnail


Authors

Atanu Bhattacharjee

Birender Balain

James Richardson

Sally Roberts



Abstract

Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, including artery, vein, cord lining, and Wharton's jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics.

Citation

Mennan, C., Wright, K., Bhattacharjee, A., Balain, B., Richardson, J., & Roberts, S. (2013). Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord. BioMed Research International, 2013, Article 916136. https://doi.org/10.1155/2013/916136

Journal Article Type Article
Acceptance Date Jun 13, 2013
Publication Date Jun 13, 2013
Journal BioMed Research International
Print ISSN 2314-6133
Publisher Hindawi
Peer Reviewed Peer Reviewed
Volume 2013
Article Number 916136
DOI https://doi.org/10.1155/2013/916136
Keywords cell differentiation, cell proliferation, cell separation, chondrogenesis, dissection, flow cytometry, humans, mesenchymal stromal cells, umbilical cord
Publisher URL http://dx.doi.org/10.1155/2013/916136

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