Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility?

Davies

Abstract

Peritoneal dialysis technique survival remains challenging due to peritonitis and long-term alterations to peritoneal membrane function and integrity. Up to now, the development of less bio-incompatible dialysis solutions have not had a major impact on these aspects of the therapy. A novel approach, supplementing dialysis solutions with a cytoprotective additive, alanyl-glutamine, has shown benefits to surrogate biomarkers of cell function in a randomized controlled study.

Citation

Davies. (2018). Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility?. Kidney International, 1050 -1052. https://doi.org/10.1016/j.kint.2018.09.012

• Acceptance Date: Nov 19, 2018
• Publication Date: Dec 1, 2018
• Journal: Kidney International
• Print ISSN: 0085-2538
• Publisher: Elsevier
• Pages: 1050 -1052
• DOI: https://doi.org/10.1016/j.kint.2018.09.012
• Keywords: peritonitis, peritoneal dialysis, dialysis
• Publisher URL: http://doi.org.10.1016/j.kint.2018.09.012