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Transient changes during microwave ablation simulation : a comparative shape analysis.

Kernot, D; Yang, J; Williams, N; Thomas, T; Ledger, P; Arora, H; van Loon, R

Transient changes during microwave ablation simulation : a comparative shape analysis. Thumbnail


Authors

D Kernot

J Yang

N Williams

T Thomas

H Arora

R van Loon



Abstract

Microwave ablation therapy is a hyperthermic treatment for killing cancerous tumours whereby microwave energy is dispersed into a target tissue region. Modelling can provide a prediction for the outcome of ablation, this paper explores changes in size and shape of temperature and Specific absorption rate fields throughout the course of simulated treatment with different probe concepts. Here, an axisymmetric geometry of a probe embedded within a tissue material is created, solving coupled electromagnetic and bioheat equations using the finite element method, utilizing hp discretisation with the NGSolve library. Results show dynamic changes across all metrics, with different responses from different probe concepts. The sleeve probe yielded the most circular specific absorption rate pattern with circularity of 0.81 initially but suffered the largest reduction throughout ablation. Similarly, reflection coefficients differ drastically from their initial values, with the sleeve probe again experiencing the largest change, suggesting that it is the most sensitive the changes in the tissue dielectric properties in these select probe designs. These collective characteristic observations highlight the need to consider dielectric property changes and probe specific responses during the design cycle.

Citation

Kernot, D., Yang, J., Williams, N., Thomas, T., Ledger, P., Arora, H., & van Loon, R. (2022). Transient changes during microwave ablation simulation : a comparative shape analysis. Biomechanics and Modeling in Mechanobiology, https://doi.org/10.1007/s10237-022-01646-6

Acceptance Date Oct 4, 2022
Publication Date Oct 26, 2022
Journal Biomechanics and Modeling in Mechanobiology
Print ISSN 1617-7959
Publisher Springer Verlag
DOI https://doi.org/10.1007/s10237-022-01646-6
Keywords microwave ablation (MWA); bioheat; hyperthermal treatment; numerical simulation; shape analysis; temperature sensitivity
Publisher URL https://link.springer.com/article/10.1007/s10237-022-01646-6#article-info

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