Maintenance and Acceleration of Pericellular Matrix Formation within 3D Cartilage Cell Culture Models

Owida, Hamza A.; Kuiper, Nicola L.; Yang, Ying

Abstract

In native articular cartilage, chondrocytes are surrounded by a thin pericellular matrix (PCM) forming chondrons. The PCM is exclusively rich in type VI collagen. The retention of the PCM has a significant influence on the metabolic activity of the chondrocytes.

Citation

Owida, H. A., Kuiper, N. L., & Yang, Y. (2021). Maintenance and Acceleration of Pericellular Matrix Formation within 3D Cartilage Cell Culture Models. Cartilage, 13(2_suppl), 847S-861S. https://doi.org/10.1177/1947603519870839

• Journal Article Type: Article
• Online Publication Date: Aug 28, 2019
• Publication Date: 2021-12
• Deposit Date: Jun 2, 2023
• Journal: CARTILAGE
• Print ISSN: 1947-6035
• Electronic ISSN: 1947-6043
• Publisher: SAGE Publications
• Peer Reviewed: Peer Reviewed
• Volume: 13
• Issue: 2_suppl
• Pages: 847S-861S
• DOI: https://doi.org/10.1177/1947603519870839
• Keywords: Physical Therapy, Sports Therapy and Rehabilitation; Biomedical Engineering; Immunology and Allergy