Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches

McIntyre, Patrick J.; Collins, Patrick M.; Vrzal, Lukáš; Birchall, Kristian; Arnold, Laurence H.; Mpamhanga, Chido; Coombs, Peter J.; Burgess, Selena G.; Richards, Mark W.; Winter, Anja; Veverka, Václav; Delft, Frank von; Merritt, Andy; Bayliss, Richard

Patrick J. McIntyre

Patrick M. Collins

Lukáš Vrzal

Kristian Birchall

Laurence H. Arnold

Chido Mpamhanga

Peter J. Coombs

Selena G. Burgess

Mark W. Richards

Anja Winter a.winter@keele.ac.uk

Václav Veverka

Frank von Delft

Andy Merritt

Richard Bayliss

Journal Article Type	Article
Online Publication Date	Oct 30, 2017
Publication Date	Nov 17, 2017
Deposit Date	Jun 5, 2023
Journal	ACS Chemical Biology
Print ISSN	1554-8929
Electronic ISSN	1554-8937
Publisher	American Chemical Society
Peer Reviewed	Peer Reviewed
Volume	12
Issue	11
Pages	2906-2914
DOI	https://doi.org/10.1021/acschembio.7b00537
Keywords	Molecular Medicine; General Medicine; Biochemistry