Camera-enabled techniques for organic synthesis

Ley, Steven V; Ingham, Richard J; O’Brien, Matthew; Browne, Duncan L

Abstract

A great deal of time is spent within synthetic chemistry laboratories on non-value-adding activities such as sample preparation and work-up operations, and labour intensive activities such as extended periods of continued data collection. Using digital cameras connected to computer vision algorithms, camera-enabled apparatus can perform some of these processes in an automated fashion, allowing skilled chemists to spend their time more productively. In this review we describe recent advances in this field of chemical synthesis and discuss how they will lead to advanced synthesis laboratories of the future.

Citation

Ley, S. V., Ingham, R. J., O’Brien, M., & Browne, D. L. (in press). Camera-enabled techniques for organic synthesis. Beilstein Journal of Organic Chemistry, 9, 1051-1072. https://doi.org/10.3762/bjoc.9.118

• Journal Article Type: Review
• Acceptance Date: May 23, 2013
• Online Publication Date: May 31, 2013
• Deposit Date: Jun 14, 2023
• Journal: Beilstein Journal of Organic Chemistry
• Print ISSN: 1860-5397
• Publisher: Beilstein-Institut
• Peer Reviewed: Peer Reviewed
• Volume: 9
• Pages: 1051-1072
• DOI: https://doi.org/10.3762/bjoc.9.118
• Keywords: Organic Chemistry; automation; computer vision; digital camera; flow chemistry; machine-assisted synthesis