Automated pupillometry in space neuroscience

Shirah, Bader H.; Sen, Jon; Naaman, Nada K.; Pandya, Shawna

Abstract

Modern pupillometers are automated, thereby providing an objective, accurate, and reliable evaluation of various aspects of the pupillary light reflex at precision levels that were previously unobtainable. There are many gaps in knowledge regarding pupil size and pupillary light reflex in nervous system changes related to space travel given the previous lack of a precise method to quantitatively measure it. Automated pupillometry has not been used previously in space. This novel tool has promising uses in altered gravity environments as a sensitive non-invasive tool to determine alterations due to headward fluid shifts and elevated intracranial pressure. This article discusses the potential use of automated pupillometry in space for monitoring of astronaut health and neurological pathology.

• Journal Article Type: Article
• Acceptance Date: Jan 16, 2023
• Online Publication Date: Jan 18, 2023
• Publication Date: 2023-05
• Deposit Date: Jun 29, 2023
• Journal: Life Sciences in Space Research
• Print ISSN: 2214-5532
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 37
• Pages: 1-2
• DOI: https://doi.org/10.1016/j.lssr.2023.01.004
• Keywords: Health, Toxicology and Mutagenesis; Astronomy and Astrophysics; Ecology; Radiation; Agricultural and Biological Sciences (miscellaneous)
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S221455242300010X?via%3Dihub
• Additional Information: This article is maintained by: Elsevier; Article Title: Automated pupillometry in space neuroscience; Journal Title: Life Sciences in Space Research; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.lssr.2023.01.004; Content Type: article; Copyright: © 2023 The Committee on Space Research (COSPAR). Published by Elsevier B.V. All rights reserved.