Iodoarene-catalyzed cyclizations of unsaturated amides

Moran, Wesley; Alhalib, Ali; Kamouka, Somaia

Abstract

The cyclization of N-alkenylamides catalyzed by iodoarenes under oxidative conditions is presented. Five-, six-, and seven-membered rings with a range of substitutions can be prepared by this route. Preliminary data from the use of chiral iodoarenes as precatalysts show that enantiocontrol is feasible.

Citation

Moran, W., Alhalib, A., & Kamouka, S. (2015). Iodoarene-catalyzed cyclizations of unsaturated amides. Organic Letters, https://doi.org/10.1021/acs.orglett.5b00333

• Journal Article Type: Letter
• Online Publication Date: Mar 5, 2015
• Publication Date: Mar 20, 2015
• Deposit Date: Mar 11, 2024
• Journal: Organic Letters
• Print ISSN: 1523-7060
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1021/acs.orglett.5b00333