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The 2024 British Society for Rheumatology guideline for management of systemic sclerosis—executive summary

Denton, Christopher P; De Lorenzis, Enrico; Roblin, Elen; Goldman, Nina; Alcacer-Pitarch, Begonya; Blamont, Emma; Buch, Maya H; Carulli, Maresa; Cotton, Caroline; Del Galdo, Francesco; Derrett-Smith, Emma; Douglas, Karen; Farrington, Sue; Fligelstone, Kim; Gompels, Luke; Griffiths, Bridget; Herrick, Ariane; Hughes, Michael; Pain, Clare; Pantano, Georgina; Pauling, John D; Prabu, Athiveeraramapandian; O’Donoghue, Nuala; Renzoni, Elisabetta A; Royle, Jeremy; Samaranayaka, Muditha; Spierings, Julia; Tynan, Aoife; Warburton, Louise; Ong, Voon H

Authors

Christopher P Denton

Enrico De Lorenzis

Elen Roblin

Nina Goldman

Begonya Alcacer-Pitarch

Emma Blamont

Maya H Buch

Maresa Carulli

Caroline Cotton

Francesco Del Galdo

Emma Derrett-Smith

Karen Douglas

Sue Farrington

Kim Fligelstone

Luke Gompels

Bridget Griffiths

Ariane Herrick

Michael Hughes

Clare Pain

Georgina Pantano

John D Pauling

Athiveeraramapandian Prabu

Nuala O’Donoghue

Elisabetta A Renzoni

Jeremy Royle

Muditha Samaranayaka

Julia Spierings

Aoife Tynan

Louise Warburton

Voon H Ong



Abstract

This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience, as well as patient organization representatives. It is an update of the previous 2015 SSc guideline. The recommendations were developed and agreed by the group and are underpinned by published evidence, assessed by systematic literature review and reinforced by collective expert opinion of the group. It considers all aspects of SSc including general management, treatment of organ-based complications, including cardiopulmonary, renal and gastrointestinal tract manifestations, as well as broader impact of disease. Whilst it is focused on adults with SSc we expect that the guideline will be relevant to people of all ages and expert input and review by paediatric rheumatologists and other relevant specialists considered where the guideline was, or may not be, applicable to young people with SSc and juvenile-onset disease. In addition to providing guidance on disease assessment and management the full guideline also considers service organization within the National Health Service and future approaches to audit of the guideline. The lay summary that accompanies this abstract can be found in Supplemental information 1.

Citation

Denton, C. P., De Lorenzis, E., Roblin, E., Goldman, N., Alcacer-Pitarch, B., Blamont, E., Buch, M. H., Carulli, M., Cotton, C., Del Galdo, F., Derrett-Smith, E., Douglas, K., Farrington, S., Fligelstone, K., Gompels, L., Griffiths, B., Herrick, A., Hughes, M., Pain, C., Pantano, G., …Ong, V. H. (in press). The 2024 British Society for Rheumatology guideline for management of systemic sclerosis—executive summary. Rheumatology, https://doi.org/10.1093/rheumatology/keae390

Journal Article Type Article
Acceptance Date Apr 8, 2024
Online Publication Date Sep 11, 2024
Deposit Date Sep 20, 2024
Journal Rheumatology
Print ISSN 1462-0324
Electronic ISSN 1462-0332
Publisher Oxford University Press
Peer Reviewed Peer Reviewed
DOI https://doi.org/10.1093/rheumatology/keae390
Keywords scleroderma, systemic sclerosis, interstitial lung disease, guideline, management
Public URL https://keele-repository.worktribe.com/output/923102
Publisher URL https://academic.oup.com/rheumatology/advance-article/doi/10.1093/rheumatology/keae390/7750185?login=true