Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models

Ranjbar, Jacob; Njoroge, Wanjiku; Gibbins, Jonathan M.; Roach, Paul; Yang, Ying; Harper, Alan G. S.

doi:10.3390/gels9060477

All Outputs (3)

Magnetic Coagulometry: Towards a New Nanotechnological Tool for ex vivo Monitoring Coagulation in Human Whole Blood (2023)
Journal Article

Blood clotting disorders consisting of unwanted blood clot formation or excessive bleeding are some of the main causes of death worldwide. However, there are significant limitations in the current methods used to clinically monitoring the dynamics of... Read More about Magnetic Coagulometry: Towards a New Nanotechnological Tool for ex vivo Monitoring Coagulation in Human Whole Blood.

Iron oxide nanoparticles as a new tool for treating cardiovascular diseases (2023)
Conference Proceeding

Thrombotic events are a major cause of death and disability worldwide. Thrombolysis with the clot busting drug tissue plasminogen activator (tPA) or thromboprophylaxis using anticoagulants such as heparin are frontline treatments for thrombotic disea... Read More about Iron oxide nanoparticles as a new tool for treating cardiovascular diseases.

Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models (2023)
Journal Article

Current in vitro thrombosis models utilise simplistic 2D surfaces coated with purified components of the subendothelial matrix. The lack of a realistic humanised model has led to greater study of thrombus formation in in vivo tests in animals. Here w... Read More about Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models.