Navitoclax augments the activity of carboplatin and paclitaxel combinations in ovarian cancer cells
(2012)
Journal Article
Stamelos, V. A., Robinson, E., Redman, C. W., & Richardson, A. (2013). Navitoclax augments the activity of carboplatin and paclitaxel combinations in ovarian cancer cells. Gynecologic Oncology, 128(2), 377-382. https://doi.org/10.1016/j.ygyno.2012.11.019
All Outputs (2)
Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine. (2012)
Journal Article
Richardson, A., Stamelos, V., & Redman, C. (2012). Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine. Journal of Molecular Signaling, 12 - ?. https://doi.org/10.1186/1750-2187-7-12BH3 mimetics such as ABT-737 and navitoclax bind to the BCL-2 family of proteins and induce apoptosis through the intrinsic apoptosis pathway. There is considerable variability in the sensitivity of different cells to these drugs. Understanding the m... Read More about Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine..