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All Outputs (126)

O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT) (2020)
Presentation / Conference
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., …Roddy, E. (2020, April). O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT). Presented at British Society for Rheumatology Annual Conference 2020, Glasgow, Scotland, UK

Background Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited. The HIT trial compared the clinical and cost-effectiveness of an ultrasound-guided intra-articular hip injection (USGI) of 4... Read More about O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT).

Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial (2020)
Journal Article
Hill, J., Garvin, S., Chen, Y., Cooper, V., Wathall, S., Saunders, B., …Foster, N. E. (2020). Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial. BMC Family Practice, 21, Article 30. https://doi.org/10.1186/s12875-019-1074-9

Background: Musculoskeletal (MSK) pain from the five most common presentations to primary care (back, neck, shoulder, knee or multi-site pain), where the majority of patients are managed, is a costly global health challenge. At present, first-line de... Read More about Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial.

Costing Methodology and Key Drivers of Health Care Costs Within Economic Analyses in Musculoskeletal Community and Primary Care Services: A Systematic Review of the Literature. (2020)
Journal Article
Burgess, R., Hall, J., Bishop, A., Lewis, M., & Hill, J. (2020). Costing Methodology and Key Drivers of Health Care Costs Within Economic Analyses in Musculoskeletal Community and Primary Care Services: A Systematic Review of the Literature. Journal of Primary Care & Community Health, https://doi.org/10.1177/2150132719899763

Background: Identifying variation in musculoskeletal service costs requires the use of specific standardized metrics. There has been a large focus on costing, efficiency, and standardized metrics within the acute musculoskeletal setting, but far less... Read More about Costing Methodology and Key Drivers of Health Care Costs Within Economic Analyses in Musculoskeletal Community and Primary Care Services: A Systematic Review of the Literature..

Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT) (2019)
Presentation / Conference
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., …Roddy, E. (2019, November). Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT). Paper presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT).

Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain. (2019)
Journal Article
Lewis. (2019). Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain. Physical Therapy, 1551-1561. https://doi.org/10.1093/ptj/pzz107

BACKGROUND: Pregnancy-related low back pain and pelvic girdle pain (LBP/PGP) are common and negatively impact the lives of many pregnant women. Several patient-based outcome instruments measure treatment effect but there is no consensus about which m... Read More about Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain..

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care (2019)
Journal Article
Roddy, E., Clarkson, K., Bucknall, M., Mehta, R., Oppong, R., Avery, A., …Mallen, C. (2019). Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care. Annals of the Rheumatic Diseases, 79(2), https://doi.org/10.1136/annrheumdis-2019-216154

OBJECTIVES: To compare the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care. METHODS: This was a multicentre open-label randomised trial. Adults with a gout flare recruited from 100 general prac... Read More about Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.

Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs (2019)
Conference Proceeding
Lewis, M., Bromley, K., McCray, G., Sutton, C., & Lancaster, G. (2019). Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs.

Introduction: The current CONSORT guidelines for reporting of pilot trials do not recommend hypothesis testing of clinical outcomes on the basis of a pilot trial being under-powered to detect such differences and this being the aim of the main tria... Read More about Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs.

Effect-based traffic light progression criteria for pilot studies (2019)
Presentation / Conference
McCray, G., Lewis, M., Bromley, K., & Lancaster, G. (2019, October). Effect-based traffic light progression criteria for pilot studies. Paper presented at 5th International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK

Meeting abstract, from the 5th International Clinical Trials Methodology Conference (ICTMC 2019).

Predictors of Functional Outcome in Musculoskeletal Healthcare: An Umbrella Review (2019)
Journal Article
Burgess, R., Mansell, G., Bishop, A., Lewis, M., & Hill, J. (2019). Predictors of Functional Outcome in Musculoskeletal Healthcare: An Umbrella Review. European Journal of Pain, 24(1), 51-70. https://doi.org/10.1002/ejp.1483

BACKGROUND Multiple cohort and systematic review studies exist, reporting independent predictive factors associated with outcome in musculoskeletal populations. These studies have found evidence for a number of 'generic' factors that have been shown... Read More about Predictors of Functional Outcome in Musculoskeletal Healthcare: An Umbrella Review.

Systematic Review of Decision Analytic Modelling in Economic Evaluations of Low Back Pain and Sciatica. (2019)
Journal Article
Hall, J. A., Konstantinou, K., Lewis, M., Oppong, R., Ogollah, R., & Jowett, S. (2019). Systematic Review of Decision Analytic Modelling in Economic Evaluations of Low Back Pain and Sciatica. Applied Health Economics and Health Policy, 17, 467-491. https://doi.org/10.1007/s40258-019-00471-w

BACKGROUND: Low back pain (LBP) and sciatica place significant burden on individuals and healthcare systems, with societal costs alone likely to be in excess of £15 billion. Two recent systematic reviews for LBP and sciatica identified a shortage of... Read More about Systematic Review of Decision Analytic Modelling in Economic Evaluations of Low Back Pain and Sciatica..

Can patients with low health literacy be identified from routine primary care health records? A cross-sectional and prospective analysis. (2019)
Journal Article
Campbell, P., Lewis, M., Chen, Y., Lacey, R., Rowlands, G., & Protheroe, J. (2019). Can patients with low health literacy be identified from routine primary care health records? A cross-sectional and prospective analysis. BMC Family Practice, 101 -?. https://doi.org/10.1186/s12875-019-0994-8

BACKGROUND: People with low health literacy (HL) are at increased risk of poor health outcomes, and receive less benefit from healthcare services. However, healthcare practitioners can effectively adapt healthcare information if they are aware of th... Read More about Can patients with low health literacy be identified from routine primary care health records? A cross-sectional and prospective analysis..

Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm (2019)
Journal Article
Konstantinou, K., Dunn, K., Windt, D., Ogollah, R., Jasani, V., & Foster, N. (2019). Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-019-2686-x

Background Sciatica is a painful condition managed by a stepped care approach for most patients. Currently, there are no decision-making tools to guide matching care pathways for patients with sciatica without evidence of serious pathology, early in... Read More about Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm.

Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis (2019)
Journal Article
Kigozi, J., Konstantinou, K., Ogollah, R., Dunn, K., Lewis, M., & Jowett, S. (2019). Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis. BMC Health Services Research, https://doi.org/10.1186/s12913-019-4257-0

Background There is limited research on the economic burden of low back-related leg pain, including sciatica. The aim of this study was to describe healthcare resource utilisation and factors associated with cost and health outcomes in primary care... Read More about Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis.

Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study) (2019)
Journal Article
Littlewood, C., Bateman, M., Cooke, K., Hennnings, S., Cookson, T., Bromley, K., …Foster, N. E. (2019). Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study). Trials, 20, Article 328. https://doi.org/10.1186/s13063-019-3407-3

Background Shoulder pain is a highly prevalent complaint and disorders of the rotator cuff, including tears, are thought to be the most common cause. The number of operations repair the torn rotator cuff has risen significantly in recent years. Whil... Read More about Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study).

Models used for case-mix adjustment of patient reported outcome measures (PROMs) in musculoskeletal healthcare: A systematic review of the literature. (2019)
Journal Article
Lewis, M., & Hill, J. (2019). Models used for case-mix adjustment of patient reported outcome measures (PROMs) in musculoskeletal healthcare: A systematic review of the literature. Physiotherapy, 137-146. https://doi.org/10.1016/j.physio.2018.10.002

BACKGROUND: Case-mix adjustment is an established method to take account of variations across cohorts in baseline patient factors, when comparing health outcomes. Although commonplace, there is a lack of evidence as to the most appropriate case-mix... Read More about Models used for case-mix adjustment of patient reported outcome measures (PROMs) in musculoskeletal healthcare: A systematic review of the literature..

The impact of inadequate health literacy in a musculoskeletal pain population (2018)
Journal Article
Lacey, R., Campbell, P., Lewis, M., & Protheroe, J. (2018). The impact of inadequate health literacy in a musculoskeletal pain population. https://doi.org/10.3928/24748307-20181101-01

Musculoskeletal conditions are a major cause of ill-health and disability. Inadequate health literacy may partly explain why musculoskeletal self-management programmes are not effective for some patients. This study prospectively evaluates the impact... Read More about The impact of inadequate health literacy in a musculoskeletal pain population.

Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain (2018)
Journal Article
Healey, E. L., Afolabi, E. K., Lewis, M., Edwards, J. J., Jordan, K. P., Finney, A., …Dziedzic, K. S. (2018). Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain. BMC Musculoskeletal Disorders, 19, Article 295. https://doi.org/10.1186/s12891-018-2196-2

Background Osteoarthritis (OA) is a leading cause of pain and disability. NICE OA guidelines (2008) recommend that patients with OA should be offered core treatments in primary care. Assessments of OA management have identified a need to improve pri... Read More about Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain.

A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol (2018)
Journal Article
Paskins, Z., Hughes, G., Myers, H., Hughes, E., Hennings, S., Cherrington, A., …Roddy, E. (2018). A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol. BMC Musculoskeletal Disorders, 19, Article 218. https://doi.org/10.1186/s12891-018-2153-0

BACKGROUND: Evidence on the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis is limited and conflicting. The primary objective of the Hip Injection Trial (HIT) is to compare pain intensity over 6 months, in people with... Read More about A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol.

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials (2018)
Report
Hay, E., Dziedzic, K., Foster, N., Peat, G., van der Windt, D., Bartlam, B., …Croft, P. (2018). Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials. NIHR. PGfAR as project number RP-PG-0407-10386. Secretary of State for Health and Social Care

Background Osteoarthritis (OA) is the most common long-term condition managed in UK general practice. However, care is suboptimal despite evidence that primary care and community-based interventions can reduce OA pain and disability. Objectives Th... Read More about Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials.