All Outputs (3)

Antiepileptic drugs and the fetal epigenome (2012)
Journal Article
Emes, R. D., Clifford, H., Haworth, K. E., Farrell, W. E., Fryer, A. A., Carroll, W. D., …KM, I. (2013). Antiepileptic drugs and the fetal epigenome. Epilepsia, 54(1), e16-e19. https://doi.org/10.1111/j.1528-1167.2012.03673.x

Antiepileptic drugs (AEDs) can lower maternal folate and increase maternal homocysteine levels, which are known to affect the methyl cycle and hence DNA methylation levels. The influence of in utero exposure to AEDs on fetal DNA methylation was inves... Read More about Antiepileptic drugs and the fetal epigenome.

Managing demand for laboratory tests: a laboratory toolkit (2012)
Journal Article
Fryer, A. A., & Smellie, W. S. A. (2013). Managing demand for laboratory tests: a laboratory toolkit. Journal of Clinical Pathology, 66(1), 62-72. https://doi.org/10.1136/jclinpath-2011-200524

Healthcare budgets worldwide are facing increasing pressure to reduce costs and improve efficiency, while maintaining quality. Laboratory testing has not escaped this pressure, particularly since pathology investigations cost the National Health Serv... Read More about Managing demand for laboratory tests: a laboratory toolkit.

Limitations of glycosylated haemoglobin (HbA1c) in diabetes screening (2012)
Journal Article
WF Hanna, F., Geen, J., Issa, B. G., Tahrani, A. A., & Fryer, A. A. (2012). Limitations of glycosylated haemoglobin (HbA1c) in diabetes screening. Practical Diabetes, 29(1), 29-31. https://doi.org/10.1002/pdi.1653

Recently, glycosylated haemoglobin (HbA1c) has been recommended by the American Diabetes Association (ADA), the World Health Organisation and subsequently by many other professional bodies as a diagnostic tool for diabetes mellitus. However, the cut-... Read More about Limitations of glycosylated haemoglobin (HbA1c) in diabetes screening.