All Outputs (2)

Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations (2014)
Journal Article
Glossop, J. R., Emes, R. D., Nixon, N. B., Haworth, K. E., Packham, J. C., Dawes, P. T., …Farrell, W. E. (2014). Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations. Epigenetics, 9(9), 1228-1237. https://doi.org/10.4161/epi.29718

Changes to the DNA methylome have been described in patients with rheumatoid arthritis (RA). In previous work, we reported genome-wide methylation differences in T-lymphocyte and B-lymphocyte populations from healthy individuals. Now, using HumanMeth... Read More about Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations.

263. Genome-Wide DNA Methylation Profiling Identifies Distinct Changes in T- and B-Cell Populations from Patients with Rheumatoid Arthritis (2014)
Presentation / Conference
Glossop, J. R., Nixon, N. B., Emes, R. D., Haworth, K. E., Packham, J. C., Dawes, P. T., …Farrell, W. E. (2014, April). 263. Genome-Wide DNA Methylation Profiling Identifies Distinct Changes in T- and B-Cell Populations from Patients with Rheumatoid Arthritis. Paper presented at Rheumatology 2014, Liverpool, UK

Background: DNA methylation is one of several epigenetic mechanisms that impacts on gene expression without underlying changes to the DNA sequence. Recent studies describe changes to the DNA methylome in RA. To date however, no systematic genome-wide... Read More about 263. Genome-Wide DNA Methylation Profiling Identifies Distinct Changes in T- and B-Cell Populations from Patients with Rheumatoid Arthritis.