All Outputs (5)

Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer (2016)
Journal Article
Kitchen, M. O., Bryan, R. T., Emes, R. D., Glossop, J. R., Luscombe, C., Cheng, K. K., …Farrell, W. E. (2016). Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer. Epigenetics, 11(3), 237-246. https://doi.org/10.1080/15592294.2016.1154246

High-grade non-muscle invasive bladder cancer (HG-NMIBC) is a clinically unpredictable disease with greater risks of recurrence and progression relative to their low-intermediate-grade counterparts. The molecular events, including those affecting the... Read More about Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer.

DNA methylation at diagnosis is associated with response to disease-modifying drugs in early rheumatoid arthritis (2016)
Journal Article
Glossop, J. R., Nixon, N. B., Emes, R. D., Sim, J., Packham, J. C., Mattey, D. L., …Fryer, A. A. (2017). DNA methylation at diagnosis is associated with response to disease-modifying drugs in early rheumatoid arthritis. Epigenomics, 9(4), 419-428. https://doi.org/10.2217/epi-2016-0042

Relationship Between Anemia and Mortality Outcomes in a National Acute Coronary Syndrome Cohort: Insights from the UK Myocardial Ischemia National Audit Project Registry (2016)
Journal Article
Mamas, M. A., Shing Kwok, C., Kontopantelis, E., Fryer, A. A., Buchan, I., Bachmann, M. O., …Myint, P. K. (2016). Relationship Between Anemia and Mortality Outcomes in a National Acute Coronary Syndrome Cohort: Insights from the UK Myocardial Ischemia National Audit Project Registry. Journal of the American Heart Association, 5(11), https://doi.org/10.1161/JAHA.116.003348

BACKGROUND: We aim to determine the prevalence of anemia in acute coronary syndrome (ACS) patients and compare their clinical characteristics, management, and clinical outcomes to those without anemia in an unselected national ACS cohort. METHODS AND... Read More about Relationship Between Anemia and Mortality Outcomes in a National Acute Coronary Syndrome Cohort: Insights from the UK Myocardial Ischemia National Audit Project Registry.

Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis (2016)
Journal Article
Wu, P., Shing Kwok, C., Haththotuwa, R., Kotronias, R. A., Babu, A., Fryer, A. A., …Mamas, M. A. (2016). Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis. Diabetologia, 59, 2518-2526. https://doi.org/10.1007/s00125-016-4098-x

Aims/hypothesis: Pre-eclampsia is a pregnancy-specific multi-system disorder and a state of physiological insulin resistance. Our aim is to systematically evaluate and quantify the evidence on the relationship between pre-eclampsia and the future ris... Read More about Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis.

THE PREVALENCE, PREDICTORS AND OUTCOMES ASSOCIATED WITH ANAEMIA AMONG PATIENTS THAT PRESENT WITH ACS: INSIGHTS FROM THE UK MINAP REGISTRY (2016)
Journal Article
Kwok, C. S., Mamas, A. M., Kontopantelis, E., Fryer, A. A., Buchan, I., Bachmann, M. O., …Myint, P. K. (2016). THE PREVALENCE, PREDICTORS AND OUTCOMES ASSOCIATED WITH ANAEMIA AMONG PATIENTS THAT PRESENT WITH ACS: INSIGHTS FROM THE UK MINAP REGISTRY. Heart, 102(S6), A76-A76. https://doi.org/10.1136/heartjnl-2016-309890.107

Background Data from both registry and post-hoc analysis of randomised controlled trials have suggested that the burden of anaemia among patients admitted with acute coronary syndrome (ACS) is significant. However, current guidelines fail to offer fi... Read More about THE PREVALENCE, PREDICTORS AND OUTCOMES ASSOCIATED WITH ANAEMIA AMONG PATIENTS THAT PRESENT WITH ACS: INSIGHTS FROM THE UK MINAP REGISTRY.