Skip to main content

Research Repository

Advanced Search

All Outputs (429)

Case-finding for depression in primary care (CAIRO): a multicentre, cross-sectional study in England (2025)
Journal Article
Lawton, S. A., Mallen, C., Chew-Graham, C., Kingstone, T., Muller, S., Lewis, S., Bajpai, R., & Helliwell, T. (2025). Case-finding for depression in primary care (CAIRO): a multicentre, cross-sectional study in England. BMJ Open, 15(6), https://doi.org/10.1136/bmjopen-2024-095040

Objectives To examine the number of patients screening positive for depression, while self-completing an automated check-in screen prior to a general practice consultation.

Design A descriptive cross-sectional study.

Setting 10 general practice... Read More about Case-finding for depression in primary care (CAIRO): a multicentre, cross-sectional study in England.

Behavioural activation for low mood and anxiety in male frontline NHS workers (BALM): a pre-post intervention study (2025)
Journal Article
Galdas, P., Bailey, D., Bell, S., Bosanquet, K., Chew-Graham, C., Ekers, D., Gilbody, S., Littlewood, E., Mawhinney, M., Stevens, H., Webb, K., & McMillan, D. (2025). Behavioural activation for low mood and anxiety in male frontline NHS workers (BALM): a pre-post intervention study. BMJ Open, 15(6), https://doi.org/10.1136/bmjopen-2024-094214

Objectives: To evaluate the impact and acceptability of a tailored, gender-responsive behavioural activation (BA) intervention for improving depression and anxiety in male National Health Service (NHS) frontline workers. Design: Pre-post intervention... Read More about Behavioural activation for low mood and anxiety in male frontline NHS workers (BALM): a pre-post intervention study.

Stakeholder perceptions of supporting patients’ return-to-work in primary care: a qualitative study (2025)
Journal Article
Harrison, R., Wynne Jones, G., Parsons, V., Madan, I., Chew-Graham, C., Pemberton, J., Mansell, G., Walker-Bone, K., Foster, N. E., & Saunders, B. (2025). Stakeholder perceptions of supporting patients’ return-to-work in primary care: a qualitative study. British Journal of General Practice Open (BJGP Open), 1-17. https://doi.org/10.3399/BJGPO.2024.0280

Background
Over 2.6 million people in the UK are absent from work due to ill-health, yet, for many, accessing work-orientated vocational support to facilitate return-to-work (RTW) is challenging. The majority of fit notes are issued in primary care,... Read More about Stakeholder perceptions of supporting patients’ return-to-work in primary care: a qualitative study.

Perceptions and Significance of Long Covid Diagnoses From the Perspectives of Children and Young People With Long Covid, Their Parents and Professionals (2025)
Journal Article
Faux‐Nightingale, A., Saunders, B., Burton, C., Chew‐Graham, C. A., Somayajula, G., Twohig, H., & Welsh, V. (2025). Perceptions and Significance of Long Covid Diagnoses From the Perspectives of Children and Young People With Long Covid, Their Parents and Professionals. Health Expectations, 28(3), 1-11. https://doi.org/10.1111/hex.70318

Introduction: Long Covid, the patient‐preferred term, describes symptoms persisting after an acute Covid‐19 infection. Understanding the importance and meaning of a Long Covid diagnosis to children and young people (CYP), their families and professio... Read More about Perceptions and Significance of Long Covid Diagnoses From the Perspectives of Children and Young People With Long Covid, Their Parents and Professionals.

Self-harm incidence among children and young people 2019-2023: time series analysis of electronic health records in Greater Manchester, England. (2025)
Journal Article
Hussey, L. J., Kontopantelis, E., Kapur, N., Williams, R., Mok, P., Ashcroft, D. M., Garg, S., Chew Graham, C., Lovell, K., & Webb, R. T. (2025). Self-harm incidence among children and young people 2019-2023: time series analysis of electronic health records in Greater Manchester, England. BMJ Mental Health, 28(1), Article e301615. https://doi.org/10.1136/bmjment-2025-301615

BackgroundThe mental health of children and adolescents has declined in recent years. Self-harm is frequently an expression of this psychological distress.ObjectivesTo examine trends in self-harm incidence among 10-24-year olds between January 2019-D... Read More about Self-harm incidence among children and young people 2019-2023: time series analysis of electronic health records in Greater Manchester, England..

How, why, for whom and when do help-seeking interventions for anxiety and depression work among older adults? A realist review (2025)
Presentation / Conference Contribution
Fisher, T., Chew-Graham, C., Corp, N., Hider, S., Southam, J., Wong, G., & Kingstone, T. (2025, March). How, why, for whom and when do help-seeking interventions for anxiety and depression work among older adults? A realist review. Presented at BJGP Research and Publishing conference, The Lowry Hotel, Manchester, England

Background A quarter of older adults (aged ≥60 years) in the UK experience a mental health problem each year. Older adults may not seek help due to limited awareness of symptoms of mental ill-health; fear of losing independence; limited access to ser... Read More about How, why, for whom and when do help-seeking interventions for anxiety and depression work among older adults? A realist review.

Navigating discharge from Early Intervention in Psychosis Services; a qualitative study of the experiences of service users and carers (2025)
Presentation / Conference Contribution
Rickett, M., Kingstone, T., Shiers, D., Williams, R., & Chew-Graham, C. (2025, March). Navigating discharge from Early Intervention in Psychosis Services; a qualitative study of the experiences of service users and carers. Presented at BJGP Research and Publishing conference, The Lowry Hotel, Manchester, England

Background Early Intervention in Psychosis (EIP) services offer up to 3 years’ treatment to people with a first episode of psychosis. Service users (SUs) are then discharged to primary care or community mental health teams. There is limited research... Read More about Navigating discharge from Early Intervention in Psychosis Services; a qualitative study of the experiences of service users and carers.

The importance of diagnosis from the perspectives of young people with Long COVID, their parents, and healthcare professionals (2025)
Presentation / Conference Contribution
Faux-Nightingale, A., Saunders, B., Burton, C., Chew-Graham, C. A., Somayajula, G., Twohig, H., & Welsh, V. (2025, March). The importance of diagnosis from the perspectives of young people with Long COVID, their parents, and healthcare professionals. Presented at BJGP Research and Publishing conference, The Lowry Hotel, Manchester, England

Background Long COVID describes symptoms persisting after an acute COVID-19 infection.

Aim This study explores the meaning and importance of a Long COVID diagnosis from the perspectives of children and young people (CYP) with Long COVID, their par... Read More about The importance of diagnosis from the perspectives of young people with Long COVID, their parents, and healthcare professionals.

How can we improve care for perinatal anxiety (PNA) in primary care? Insights from a community engagement and involvement event (2025)
Presentation / Conference Contribution
Silverwood, V., Proctor, J., Fisher, T., Kingstone, T., Turner, K., & Chew-Graham, C. (2025, March). How can we improve care for perinatal anxiety (PNA) in primary care? Insights from a community engagement and involvement event. Presented at BJGP Research and Publishing conference, The Lowry Hotel, Manchester, England

Background Perinatal anxiety (PNA) is anxiety that occurs during pregnancy or in the twelve months postpartum. Experienced by approximately 21% of women worldwide, PNA can have a negative impact on mothers, children and their families.

Aim A commu... Read More about How can we improve care for perinatal anxiety (PNA) in primary care? Insights from a community engagement and involvement event.

E077 What is the impact of psychosocial interventions to prevent anxiety and/or depression in people with inflammatory rheumatological conditions? A systematic review (2025)
Presentation / Conference Contribution
Gray, L., Corp, N., Bjorklund, M., Kingstone, T., Chew-Graham, C., & Hider, S. (2025, April). E077 What is the impact of psychosocial interventions to prevent anxiety and/or depression in people with inflammatory rheumatological conditions? A systematic review. Poster presented at British Society for Rheumatology Annual Conference 2025, Manchester Central Convention Complex, Manchester, England, UK

Background/Aims Common mood problems such as anxiety and depression are associated with poorer outcomes for people with inflammatory rheumatological conditions. There is increasing interest in investigating whether psychosocial interventions can prev... Read More about E077 What is the impact of psychosocial interventions to prevent anxiety and/or depression in people with inflammatory rheumatological conditions? A systematic review.

Experiences and Perceptions of Self‐Harm in Rural‐Dwelling Adults: A Rapid Review of Qualitative Evidence (2025)
Journal Article
Saunders, K., Nicholls, W., Corp, N., Kingstone, T., Mughal, F., Chew‐Graham, C. A., Southam, J., & Fisher, T. (2025). Experiences and Perceptions of Self‐Harm in Rural‐Dwelling Adults: A Rapid Review of Qualitative Evidence. Health Expectations, 28(3), 1-10. https://doi.org/10.1111/hex.70268

Background: Self‐harm is associated with factors that are relevant to and exacerbated by rurality. Living in rural areas may intensify existing socio‐economic disadvantages linked to service access, employment opportunities, transport conditions and... Read More about Experiences and Perceptions of Self‐Harm in Rural‐Dwelling Adults: A Rapid Review of Qualitative Evidence.

Case-finding with the anxiety sub-scale of the Edinburgh Postnatal Depression Scale in an observational cohort: Sensitivity, specificity, and cost-effectiveness. (2025)
Journal Article
Camacho, E. M., Shields, G. E., Eisner, E., Littlewood, E., Watson, K., Chew-Graham, C. A., McMillan, D., & Gilbody, S. (in press). Case-finding with the anxiety sub-scale of the Edinburgh Postnatal Depression Scale in an observational cohort: Sensitivity, specificity, and cost-effectiveness. Journal of Affective Disorders, 381, 84-91. https://doi.org/10.1016/j.jad.2025.04.009

The Edinburgh Postnatal Depression Scale (EPDS) is effective and cost-effective for identifying postnatal depression. Postnatal anxiety is also common and can be identified by three questions on the EPDS (anxiety sub-scale). We aimed to compare EPDS... Read More about Case-finding with the anxiety sub-scale of the Edinburgh Postnatal Depression Scale in an observational cohort: Sensitivity, specificity, and cost-effectiveness..

A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT (2025)
Report
Husain, N., Lovell, K., Chew-Graham, C. A., Lunat, F., Bee, P., Pierce, M., Atif, N., Aseem, S., Bhui, K., Bower, P., Brugha, T., Chaudhry, N., Ullah, A., Davies, L., Gire, N., Sharma, D., Miah, J., Ahmed, W., Kai, J., Mirza, I., …Morriss, R. (2025). A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT. NIHR / Health Technology Assessment

Background Postnatal depression is more common in British South Asian women than white women in the United Kingdom. Despite empirical evidence suggesting the effectiveness of cognitive–behavioural therapy as a first line of treatment, little evidence... Read More about A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT.

Changes in heart failure healthcare in general practice during the COVID-19 pandemic. (2025)
Journal Article
Rothenberger, R., Blakeman, T., Chew-Graham, C. A., Forsyth, F., Hossain, M., Sowden, E., & Deaton, C. (2025). Changes in heart failure healthcare in general practice during the COVID-19 pandemic. British Journal of General Practice Open (BJGP Open), 1-26. https://doi.org/10.3399/BJGPO.2024.0138

The COVID-19 pandemic accelerated the adoption of remote healthcare for long-term condition management, including heart failure (HF). However, little is known about the experiences of this transition, knowledge developed during service transformation... Read More about Changes in heart failure healthcare in general practice during the COVID-19 pandemic..

Under‐Served Groups and Myalgic Encephalomyelitis Research Workshop; Multiple Barriers to Effective Healthcare, Research and Public Participation (2025)
Journal Article
Bolton, M. J., Chew‐Graham, C. A., & van Marwijk, H. (in press). Under‐Served Groups and Myalgic Encephalomyelitis Research Workshop; Multiple Barriers to Effective Healthcare, Research and Public Participation. Health Expectations, 28(2), 1-5. https://doi.org/10.1111/hex.70214

Public involvement in research and other initiatives for myalgic encephalomyelitis (ME) (also known as chronic fatigue syndrome) has been crucial in raising awareness of the disease and exposing inadequate healthcare and research funding. An online w... Read More about Under‐Served Groups and Myalgic Encephalomyelitis Research Workshop; Multiple Barriers to Effective Healthcare, Research and Public Participation.

Improving primary care services for imprisoned women with severe mental illness (IP-SIS) Protocol Paper (2025)
Other
Roden-Lui, G., Chew-Graham, C. A., Hard, J., Harriott, P., King, H., Mastrocola, E., & Walker, T. Improving primary care services for imprisoned women with severe mental illness (IP-SIS) Protocol Paper

Background
A gap exists in the provision of care for imprisoned women with Severe Mental Illness (SMI), both in prison and on release to mainstream primary care. Women in such settings tend to have complex mental health problems, often with comorbid... Read More about Improving primary care services for imprisoned women with severe mental illness (IP-SIS) Protocol Paper.

2763 Process evaluation of the BASIL+ trial: addressing low mood among older people (2025)
Presentation / Conference Contribution
Bosanquet, K., Newbronner, E., Coventry, P., Shearsmith, L., Littlewood, E., Bailey, D., Henry, A., Burke, L., Ryde, E., McMillan, D., Ekers, D., Gilbody, S., & Chew-Graham, C. (2024, November). 2763 Process evaluation of the BASIL+ trial: addressing low mood among older people. Presented at British Geriatrics Society Autumn Meeting 2024, Excel, London

Introduction During the COVID-19 pandemic, older adults were at risk of being socially isolated or experiencing loneliness, increasing the risk of depression. We adapted the delivery of Behavioural Activation (BA), an effective evidence-based interve... Read More about 2763 Process evaluation of the BASIL+ trial: addressing low mood among older people.

Process evaluation of the BASIL+ trial: A behavioural activation approach to addressing low mood and depression among older people with long-term conditions (2025)
Journal Article
Newbronner, E., Bosanquet, K., Coventry, P., Shearsmith, L., Littlewood, E., Bailey, D., Henry, A., Burke, L., Ryde, E., McMillan, D., Ekers, D., Gilbody, S., & Chew-Graham, C. (in press). Process evaluation of the BASIL+ trial: A behavioural activation approach to addressing low mood and depression among older people with long-term conditions. PLOS Mental Health, 2(1), 1-15. https://doi.org/10.1371/journal.pmen.0000105

Older adults are at risk of low mood and depression, which can be exacerbated by long-term physical health conditions, leading to poorer health outcomes and increased mortality. The restrictions on social mixing during the COVID-19 pandemic heightene... Read More about Process evaluation of the BASIL+ trial: A behavioural activation approach to addressing low mood and depression among older people with long-term conditions.

Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared with usual care: results from a pragmatic randomised controlled trial (2025)
Journal Article
Wang, H.-I., Gilbody, S., Littlewood, E., Baird, K., Ekers, D., McMillan, D., Bailey, D., Chew-Graham, C., Coventry, P., Fairhurst, C., Hewitt, C., & Parrott, S. (2025). Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared with usual care: results from a pragmatic randomised controlled trial. BMJ Mental Health, 28(1), 1-9. https://doi.org/10.1136/bmjment-2024-301270

Background: Depression alongside multiple long-term conditions (MLTCs) in older adults poses a critical public health challenge, worsening physical and mental health and increasing healthcare costs. COVID-19 restrictions further exacerbated these imp... Read More about Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared with usual care: results from a pragmatic randomised controlled trial.