All Outputs (7)

Endoplasmic reticulum targeting fluorescent probes to image mobile Zn2+ (2019)
Journal Article
Fang, L., Trigiante, G., Crespo-Otero, R., Hawes, C. S., Philpott, M. P., Jones, C. R., & Watkinson, M. (2019). Endoplasmic reticulum targeting fluorescent probes to image mobile Zn2+. Chemical Science, 10(47), 10881-10887. https://doi.org/10.1039/C9SC04300D

Zn2+ plays an important role in the normal function of the endoplasmic reticulum (ER) and its deficiency can cause ER stress, which is related to a wide range of diseases. In order to provide tools to better understand the role of mobile Zn2+ in ER p... Read More about Endoplasmic reticulum targeting fluorescent probes to image mobile Zn2+.

Synthesis, coordination chemistry and photophysical properties of naphtho-fused pyrazole ligands (2019)
Journal Article
Hawes, C. S. (2019). Synthesis, coordination chemistry and photophysical properties of naphtho-fused pyrazole ligands. CrystEngComm, 5152-5163. https://doi.org/10.1039/c9ce01074b

The synthesis of two p-extended pyrazole ligands is reported, with naphtho[2,1-d]-1H-pyrazole HL1 prepared in a modified Jacobson indazole synthesis from 1-amino-2-methylnaphthalene, and subsequent arylation with 2-bromopyridine giving the chelating... Read More about Synthesis, coordination chemistry and photophysical properties of naphtho-fused pyrazole ligands.

Unexpected linkage isomerism in chiral tetranuclear bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) grids (2019)
Journal Article
Hegarty, I. N., Dalton, H. L., Henwood, A. F., Hawes, C. S., & Gunnlaugsson, T. (2019). Unexpected linkage isomerism in chiral tetranuclear bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) grids. Chemical Communications, 9523-9526. https://doi.org/10.1039/c9cc03316e

The synthesis of a chiral bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) ligand is described and its coordination chemistry with Cu(NO3)2 and [Cu(MeCN)4]PF6 is explored in the crystalline phase as well as in solution. Chiral [2 × 2] tetranuc... Read More about Unexpected linkage isomerism in chiral tetranuclear bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) grids.

Substituent effects in the zinc(II) coordination chemistry of isomeric pyridylpyrazole ligands (2019)
Journal Article
Chen, P., Ge, W., Lu, Y., Wu, Z., Xu, J., Woodfine, S. E., …Hawes, C. S. (2019). Substituent effects in the zinc(II) coordination chemistry of isomeric pyridylpyrazole ligands. Journal of Coordination Chemistry, https://doi.org/10.1080/00958972.2019.1587613

Pyrazoles with unsymmetric substitution are useful ligands in coordination chemistry, but are under-developed due to synthetic challenges in accessing the pure isomers. We have prepared four new structurally related N-(2-pyridyl)-3,5-dialkylpyrazole... Read More about Substituent effects in the zinc(II) coordination chemistry of isomeric pyridylpyrazole ligands.

Glycosylated naphthalimides and naphthalimide Tröger's bases as fluorescent aggregation probes for Con A. (2019)
Journal Article
Calatrava-Perez, E., Delente, J. M., Shanmugaraju, S., Hawes, C. S., Williams, C. D., Gunnlaugsson, T., & Scanlan, E. M. (2019). Glycosylated naphthalimides and naphthalimide Tröger's bases as fluorescent aggregation probes for Con A. Organic and Biomolecular Chemistry, 17(8), 2116-2125. https://doi.org/10.1039/C8OB02980F

Herein we report the synthesis of fluorescent, glycosylated 4-amino-1,8-naphthalimide (Nap) 1, and the related 1,8-naphthalimides Tröger's bases (TBNap) 2 and 3, from 1,8-naphthalic anhydride precursors, the a-mannosides being introduced through the... Read More about Glycosylated naphthalimides and naphthalimide Tröger's bases as fluorescent aggregation probes for Con A..

Correction: Glycosylated naphthalimides and naphthalimide Tröger's bases as fluorescent aggregation probes for Con A. (2019)
Journal Article
Hawes, C. S. (2019). Correction: Glycosylated naphthalimides and naphthalimide Tröger's bases as fluorescent aggregation probes for Con A. Organic and Biomolecular Chemistry, 2287 - ?. https://doi.org/10.1039/C9OB90017A

Correction for 'Glycosylated naphthalimides and naphthalimide Tröger's bases as fluorescent aggregation probes for Con A' by Elena Calatrava-Pérez et al., Org. Biomol. Chem., 2019, DOI: 10.1039/c8ob02980f.

Crystallographic studies of 2-picolyl substituted naphthalene diimide and bis-phthalimide ligands and their supramolecular coordination chemistry (2019)
Journal Article
Hawes, C. S. (2019). Crystallographic studies of 2-picolyl substituted naphthalene diimide and bis-phthalimide ligands and their supramolecular coordination chemistry. CrystEngComm, 207-217. https://doi.org/10.1039/c8ce01756e

Here we report the synthesis of two N-(2-picolyl) substituted bis-imide ligands, N,N'-di(2-picolyl)-1,4,5,8-naphthalenetetracarboxylic diimide L1 and N,N'-di(2-picolyl)-4,4'-oxybisphthalimide L2, and describe their coordination chemistry in the cryst... Read More about Crystallographic studies of 2-picolyl substituted naphthalene diimide and bis-phthalimide ligands and their supramolecular coordination chemistry.