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All Outputs (42)

Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review. (2020)
Journal Article
Twohig, H., Owen, C., Muller, S., Mallen, C., Mitchell, C., Hider, S., …Hill, C. (2021). Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review. Journal of Rheumatology, 48(6), 883-893. https://doi.org/10.3899/jrheum.200248

OBJECTIVE: To systematically identify the outcome measures and instruments used in clinical studies of polymyalgia rheumatica (PMR) and to evaluate evidence about their measurement properties. METHODS: Searches based on the MeSH term 'polymyalgia rhe... Read More about Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review..

Comparing the use of direct observation, standardized patients and exit interviews in low- and middle-income countries: a systematic review of methods of assessing quality of primary care. (2020)
Journal Article
Mallen. (2020). Comparing the use of direct observation, standardized patients and exit interviews in low- and middle-income countries: a systematic review of methods of assessing quality of primary care. Health Policy and Planning, 341-356. https://doi.org/10.1093/heapol/czaa152

Clinical records in primary healthcare settings in low- and middle-income countries (LMIC) are often lacking or of too poor quality to accurately assess what happens during the patient consultation. We examined the most common methods for assessing h... Read More about Comparing the use of direct observation, standardized patients and exit interviews in low- and middle-income countries: a systematic review of methods of assessing quality of primary care..

Understanding the uptake of a clinical innovation for osteoarthritis in primary care: a qualitative study of knowledge mobilisation using the i-PARIHS framework. (2020)
Journal Article
Swaithes, L., Dziedzic, K., Finney, A., Cottrell, E., Jinks, C., Mallen, C., …Paskins, Z. (2020). Understanding the uptake of a clinical innovation for osteoarthritis in primary care: a qualitative study of knowledge mobilisation using the i-PARIHS framework. Implementation Science, 15, Article 95. https://doi.org/10.1186/s13012-020-01055-2

BACKGROUND: Osteoarthritis is a leading cause of pain and disability worldwide. Despite research supporting best practice, evidence-based guidelines are often not followed. Little is known about the implementation of non-surgical models of care in ro... Read More about Understanding the uptake of a clinical innovation for osteoarthritis in primary care: a qualitative study of knowledge mobilisation using the i-PARIHS framework..

Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial (2020)
Journal Article
Nathan R., H., Chris, A., Lee, B., A. John, C., David, C., D. Wyn, D., …Alexander T., C. (2020). Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial. Contemporary Clinical Trials Communications, https://doi.org/10.1016/j.cct.2020.106191

Atrial fibrillation (AF) is associated with an increased risk of stroke, enhanced stroke severity, and other comorbidities. However, AF is often asymptomatic, and frequently remains undiagnosed until complications occur. Current screening approaches... Read More about Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial.

Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature (2020)
Journal Article
Mallen. (2020). Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.13725

Background: The 2019 coronavirus disease (COVID-19) has become a global pandemic and the published literature describing the virus has grown exponentially. Methods: We conducted a systematic review of the literature to identify the symptoms, comorb... Read More about Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature.

Cohort profile: Oxford Pain, Activity and Lifestyle (OPAL) Study, a prospective cohort study of older adults in England. (2020)
Journal Article
Mallen. (2020). Cohort profile: Oxford Pain, Activity and Lifestyle (OPAL) Study, a prospective cohort study of older adults in England. BMJ Open, https://doi.org/10.1136/bmjopen-2020-037516

PURPOSE: The 'Oxford Pain, Activity and Lifestyle' (OPAL) Cohort is a longitudinal, prospective cohort study of adults, aged 65 years and older, living in the community which is investigating the determinants of health in later life. Our focus was on... Read More about Cohort profile: Oxford Pain, Activity and Lifestyle (OPAL) Study, a prospective cohort study of older adults in England..

Latent Class Growth Analysis of Gout Flare Trajectories: A Three-Year Prospective Cohort Study in Primary Care (2020)
Journal Article
Muller, Watson, Belcher, Mallen, Roddy, & Nicholls. (2020). Latent Class Growth Analysis of Gout Flare Trajectories: A Three-Year Prospective Cohort Study in Primary Care. Arthritis and Rheumatology, 72(11), 1928-1935. https://doi.org/10.1002/art.41476

Objective To investigate the existence of distinct classes of gout flare trajectories and compare their gout-specific, comorbid, and sociodemographic characteristics. Methods In a prospective cohort study, adults with gout who were registered wi... Read More about Latent Class Growth Analysis of Gout Flare Trajectories: A Three-Year Prospective Cohort Study in Primary Care.

Mortality Among Patients With Polymyalgia Rheumatica: A Retrospective Cohort Study (2020)
Journal Article
Partington, R., Muller, S., Mallen, C. D., Abdul Sultan, A., & Helliwell, T. (2021). Mortality Among Patients With Polymyalgia Rheumatica: A Retrospective Cohort Study. Arthritis Care and Research, 73(12), 1853-1857. https://doi.org/10.1002/acr.24403

OBJECTIVE: To determine whether a diagnosis of polymyalgia rheumatica (PMR) is associated with premature mortality. METHODS: We extracted anonymised electronic medical records of patients over the age of 40 years, who were eligible for linkage with t... Read More about Mortality Among Patients With Polymyalgia Rheumatica: A Retrospective Cohort Study.

Improving Empathy in Healthcare Consultations-a Secondary Analysis of Interventions. (2020)
Journal Article
Mallen. (2020). Improving Empathy in Healthcare Consultations-a Secondary Analysis of Interventions. Journal of General Internal Medicine, https://doi.org/10.1007/s11606-020-05994-w

A recent systematic review of randomised trials suggested that empathic communication improves patient health outcomes. However, the methods for training healthcare practitioners (medical professionals; HCPs) in empathy and the empathic behaviours de... Read More about Improving Empathy in Healthcare Consultations-a Secondary Analysis of Interventions..

Managing hypertension in frail oldest-old – the role of guideline use by general practitioners from 29 countries (2020)
Journal Article
Mallen. (2020). Managing hypertension in frail oldest-old – the role of guideline use by general practitioners from 29 countries. PloS one, https://doi.org/10.1371/journal.pone.0236064

Background: The best management of hypertension in frail oldest-old (=80 years of age) remains unclear while lacking guidelines providing specific recommendations.Aim, Objectives To investigate guideline use in general practitioners (GPs) and if gui... Read More about Managing hypertension in frail oldest-old – the role of guideline use by general practitioners from 29 countries.

Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial. (2020)
Journal Article
Hill, J., Garvin, S., Chen, Y., Cooper, V., Wathall, S., Bartlam, B., …Foster, N. E. (2020). Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial. JMIR Research Protocols, 9(7), https://doi.org/10.2196/17939

BACKGROUND: Musculoskeletal (MSK) pain is a major cause of pain and disability. We previously developed a prognostic tool (STarT Back Tool) with demonstrated effectiveness in guiding primary care low back pain management by supporting decision-making... Read More about Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial..

Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction (2020)
Journal Article
Clarson, L. E., Bajpai, R., Whittle, R., Belcher, J., Abdul Sultan, A., Kwok, C. S., …Mallen, C. D. (2020). Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction. Heart, 106(12), 916-922. https://doi.org/10.1136/heartjnl-2019-315511

Objectives Despite many shared risk factors and pathophysiological pathways, the risk of ischaemic heart disease (IHD) and myocardial infarction (MI) in interstitial lung disease (ILD) remains poorly understood. This lack of data could be preventing... Read More about Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction.

Using Google Trends to assess the impact of global public health days on online health information seeking behaviour in Central and South America (2020)
Journal Article
Havelka, E. M., Mallen, C. D., & Shepherd, T. A. (2020). Using Google Trends to assess the impact of global public health days on online health information seeking behaviour in Central and South America. Journal of Global Health, 10(1), https://doi.org/10.7189/jogh.10.010403

Background Public health awareness can help prevent illness and result in earlier intervention when it does occur. For this reason, health promotion and disease awareness campaigns have great potential to alleviate the global burden of disease. Glob... Read More about Using Google Trends to assess the impact of global public health days on online health information seeking behaviour in Central and South America.

Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan (2020)
Journal Article
Shepherd, T. A., Ul-Haq, Z., Ul-Haq, M., Firaz Khan, M., Afridi, A., Dikomitis, L., …Farooq, S. (2020). Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan. BMJ Open, 10(6), https://doi.org/10.1136/bmjopen-2019-034709

Introduction: There is a significant treatment gap, with only a few community-based services for people with schizophrenia in Low- and Middle-Income countries. Poor treatment adherence in schizophrenia is associated with poorer health outcomes, suici... Read More about Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan.

Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT (2020)
Journal Article
Foster, N. E., Konstantinou, K., Lewis, M., Ogollah, R., Saunders, B., Kigozi, J., …Dunn, K. M. (2020). Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT. Health Technology Assessment, 2(7), e401-e411. https://doi.org/10.3310/hta24490

BACKGROUND: Sciatica has a substantial impact on patients and society. Current care is 'stepped', comprising an initial period of simple measures of advice and analgesia, for most patients, commonly followed by physiotherapy, and then by more intensi... Read More about Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT.

Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial (2020)
Journal Article
Konstantinou, K., Lewis, M., Dunn, K., Hay, E., Van Der Windt, D., Artus, M., …Foster, N. (2020). Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial. The Lancet Rheumatology, 2(7), e401-e411. https://doi.org/10.1016/S2665-9913%2820%2930099-0

Background Sciatica has a substantial impact on individuals and society. Stratified care has been shown to lead to better outcomes among patients with non-specific low back pain, but it has not been tested for sciatica. We aimed to investigate the c... Read More about Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial.

Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study. (2020)
Journal Article
Mallen. (2020). Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study. Rheumatology, https://doi.org/10.1093/rheumatology/keaa223

Objective Statins are reported to have a potential benefit on progression of OA and on disease activity in RA, but existing evidence is conflicting. Our objective was to examine whether statins associate with reduction in the risk for joint replacem... Read More about Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study..

Trends in Incidence and Prevalence of Osteoarthritis in the United Kingdom: Findings from the Clinical Practice Research Datalink (CPRD) (2020)
Journal Article
Mallen. (2020). Trends in Incidence and Prevalence of Osteoarthritis in the United Kingdom: Findings from the Clinical Practice Research Datalink (CPRD). Osteoarthritis and Cartilage, 792-801. https://doi.org/10.1016/j.joca.2020.03.004

Objective: This study aimed to explore the incidence and prevalence of OA in the UK in 2017 and their trends from 1997 to 2017 using a large nationally representative primary care database. Design: The UK Clinical Practice Research Datalink (CPRD)... Read More about Trends in Incidence and Prevalence of Osteoarthritis in the United Kingdom: Findings from the Clinical Practice Research Datalink (CPRD).

Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction (2020)
Journal Article
Elise Clarson, L., Bajpai, R., Whittle, R., Belcher, J., Abdul Sultan, A., Shing Kwok, C., …Mallen, C. D. (2020). Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction. Heart, Article 12. https://doi.org/10.1136/heartjnl-2019-315511

Objectives Despite many shared risk factors and pathophysiological pathways, the risk of ischaemic heart disease (IHD) and myocardial infarction (MI) in interstitial lung disease (ILD) remains poorly understood. This lack of data could be preventing... Read More about Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction.