All Outputs (418)

PREVALENCE OF FRAGILITY FRACTURES AND MEDICATION PRESCRIPTION FOR OSTEOPOROSIS IN PATIENTS WITH POLYMYALGIA RHEUMATICA: RESULTS FROM THE PMR COHORT STUDY (2021)
Journal Article
Singh Sokhal, B., Hider, S. L., Paskins, Z., Muller, S., & Mallen, C. D. (2021). PREVALENCE OF FRAGILITY FRACTURES AND MEDICATION PRESCRIPTION FOR OSTEOPOROSIS IN PATIENTS WITH POLYMYALGIA RHEUMATICA: RESULTS FROM THE PMR COHORT STUDY. Rheumatology, 60(S1), Article ARTN keab246.002. https://doi.org/10.1093/rheumatology/keab246.002

Background/Aims Polymyalgia rheumatica (PMR) is one of the commonest indications for long term glucocorticoid (GC) use, leading to an increased risk of osteoporosis and fragility fractures. Clinical guidelines recommend prescribing medication includ... Read More about PREVALENCE OF FRAGILITY FRACTURES AND MEDICATION PRESCRIPTION FOR OSTEOPOROSIS IN PATIENTS WITH POLYMYALGIA RHEUMATICA: RESULTS FROM THE PMR COHORT STUDY.

The patient, clinician and healthcare perspectives in evaluating care pathways for stable chest pain. (2021)
Journal Article
Kwok, C. S., Duckett, S., Satchithananda, D., Potluri, R., Morgan-Smith, D., Bellenger, N., …Mallen, C. D. (2021). The patient, clinician and healthcare perspectives in evaluating care pathways for stable chest pain. Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine, 20(3), 143-148. https://doi.org/10.1097/HPC.0000000000000261

Chest pain is one of the most common reasons for patients to present to healthcare professionals. One of the main challenges with the management of chest pain is the wide differential diagnosis, ranging from minor chest trauma to potentially life thr... Read More about The patient, clinician and healthcare perspectives in evaluating care pathways for stable chest pain..

Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study. (2021)
Journal Article
Mamas, Mallen, & Chew-Graham. (2021). Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study. Open Heart, https://doi.org/10.1136/openhrt-2020-001498

OBJECTIVE: Most current cardiovascular disease (CVD) risk stratification tools are for people without CVD, but very few are for prevalent CVD. In this study, we developed and validated a CVD severity score in people with coronary heart disease (CHD)... Read More about Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study..

Self-management advice, exercise and foot orthoses for plantar heel pain: the TREADON pilot and feasibility randomised trial (2021)
Journal Article
Chesterton, L. S., Thomas, M. J., Hendry, G., Chen, Y., Goddin, D., Halliday, N., …Roddy, E. (2021). Self-management advice, exercise and foot orthoses for plantar heel pain: the TREADON pilot and feasibility randomised trial. Pilot and Feasibility Studies, 7, Article 92. https://doi.org/10.1186/s40814-021-00808-0

Plantar heel pain (PHP) is common and impacts negatively on physical function and quality of life. Initial treatment usually comprises analgesia and self-management advice (SMA), with referral to a physiotherapist or podiatrist recommended only when... Read More about Self-management advice, exercise and foot orthoses for plantar heel pain: the TREADON pilot and feasibility randomised trial.

Impact of changes to national guidelines on hypertension-related workload: an interrupted time series analysis in English primary care. (2021)
Journal Article
Mallen. (2021). Impact of changes to national guidelines on hypertension-related workload: an interrupted time series analysis in English primary care. British Journal of General Practice (BJGP), e296-e302. https://doi.org/10.3399/bjgp21X714281

BACKGROUND: In 2011, National Institute for Health and Care Excellence (NICE) guidelines recommended the routine use of out-of-office blood pressure (BP) monitoring for the diagnosis of hypertension. These changes were predicted to reduce unnecessary... Read More about Impact of changes to national guidelines on hypertension-related workload: an interrupted time series analysis in English primary care..

Clinical and cost-effectiveness of bracing in symptomatic knee osteoarthritis management: protocol for a multicentre, primary care, randomised, parallel-group, superiority trial. (2021)
Journal Article
Holden, M., Callaghan, M., Felson, D., Birrell, F., Nicholls, E., Jowett, S., …Peat, G. (2021). Clinical and cost-effectiveness of bracing in symptomatic knee osteoarthritis management: protocol for a multicentre, primary care, randomised, parallel-group, superiority trial. BMJ Open, 11(3), Article e048196. https://doi.org/10.1136/bmjopen-2020-048196

BACKGROUND: Brace effectiveness for knee osteoarthritis (OA) remains unclear and international guidelines offer conflicting recommendations. Our trial will determine the clinical and cost-effectiveness of adding knee bracing (matched to patients' cli... Read More about Clinical and cost-effectiveness of bracing in symptomatic knee osteoarthritis management: protocol for a multicentre, primary care, randomised, parallel-group, superiority trial..

Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention. (2021)
Journal Article
Bullock, L., Crawford-Manning, F., Cottrell, E., Fleming, J., Leyland, S., Edwards, J., …Paskins, Z. (2021). Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention. Archives of Osteoporosis, 16, 1- 17. https://doi.org/10.1007/s11657-021-00913-w

Fracture Liaison Services are recommended to deliver best practice in secondary fracture prevention. This modified Delphi survey, as part of the iFraP (Improving uptake of Fracture Prevention drug Treatments) study, provides consensus regarding tasks... Read More about Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention..

Onset of comorbidities and flare patterns within pre-existing morbidity clusters in people with gout: 5-year primary care cohort study. (2021)
Journal Article
Bajpai, R., Muller, S., Mallen, C., Watson, L., Richette, P., Hider, S. L., & Roddy, E. (2021). Onset of comorbidities and flare patterns within pre-existing morbidity clusters in people with gout: 5-year primary care cohort study. Rheumatology, 61(1), 407-412. https://doi.org/10.1093/rheumatology/keab283

OBJECTIVE: To investigate the onset of comorbidities and pattern of flares over five years according to baseline comorbidity clusters in people with gout. METHODS: In a prospective primary-care-based cohort study, adults aged =18 years with gout, wer... Read More about Onset of comorbidities and flare patterns within pre-existing morbidity clusters in people with gout: 5-year primary care cohort study..

What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline? (2021)
Journal Article
Mallen. (2021). What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?. Rheumatology, https://doi.org/10.1093/rheumatology/keab254

OBJECTIVES: To examine incidence of treatment changes due to abnormal blood-test results and, to explore rates of treatment changes due to liver, kidney and haematological blood-test abnormalities in autoimmune rheumatic diseases (AIRD) treated with... Read More about What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?.

Exploring patient views of empathic optimistic communication for osteoarthritis in primary care: A qualitative interview study using vignettes (2021)
Journal Article
Mallen. (2021). Exploring patient views of empathic optimistic communication for osteoarthritis in primary care: A qualitative interview study using vignettes. British Journal of General Practice Open (BJGP Open), https://doi.org/10.3399/BJGPO.2021.0014

BACKGROUND: Osteoarthritis (OA) causes pain and disability. An empathic optimistic consultation approach can improve patient quality of life, satisfaction with care, and reduce pain. However, expressing empathic optimism may be overlooked in busy pri... Read More about Exploring patient views of empathic optimistic communication for osteoarthritis in primary care: A qualitative interview study using vignettes.

ß-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study (2021)
Journal Article
Mamas, & Mallen. (2021). ß-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study. Rheumatology, https://doi.org/10.1093/rheumatology/keab234

OBJECTIVES: To examine the association between ß-blocker prescription and first primary-care consultation for knee osteoarthritis (OA), hip OA, knee pain and hip pain. METHODS: Data source: Clinical Practice Research Datalink. Participants aged =40?y... Read More about ß-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study.

Corrigendum to Health-related quality of life in gout in primary care: Baseline findings from a cohort study Seminars in Arthritis & Rheumatism, 48 (2018) 61-69. (2021)
Journal Article
Chandratre, P., Mallen, C., Richardson, J., Muller, S., Hider, S., Rome, K., …Roddy, E. (2022). Corrigendum to Health-related quality of life in gout in primary care: Baseline findings from a cohort study Seminars in Arthritis & Rheumatism, 48 (2018) 61-69. Seminars in Arthritis and Rheumatism, 52, Article 151800. https://doi.org/10.1016/j.semarthrit.2021.02.009

Corrigendum

Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting. (2021)
Journal Article
Mallen. (2021). Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting. Rheumatology, 4327-4339. https://doi.org/10.1093/rheumatology/keab067

OBJECTIVE: To determine the burden of comorbidities in osteoarthritis (OA) and their temporal relationships in the UK. METHODS: The Clinical Practice Research Datalink (CPRD) GOLD was used to identify people with incident OA and age, gender and pract... Read More about Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting..

Using Google Trends to assess the impact of Global Public Health Days on online health information-seeking behaviour in Arabian Peninsula (2021)
Journal Article
Ajbar, A., Shepherd, T. A., Robinson, M., Mallen, C. D., & Prior, J. A. (2021). Using Google Trends to assess the impact of Global Public Health Days on online health information-seeking behaviour in Arabian Peninsula. Journal of Egyptian Public Health Association, 94, Article 4. https://doi.org/10.1186/s42506-020-00063-w

BACKGROUND: Global Public Health Days (GPHD) are public health interventions which serve to improve public awareness of specific health conditions. Google Trends is a publicly available tool that allows the user to view the popularity of a searched k... Read More about Using Google Trends to assess the impact of Global Public Health Days on online health information-seeking behaviour in Arabian Peninsula.

Misdiagnosis of Acute Myocardial Infarction: A Systematic Review of the Literature (2021)
Journal Article
Kwok, C. S., Bennett, S., Azam, Z., Welsh, V., Potluri, R., Loke, Y. K., & Mallen, C. D. (2021). Misdiagnosis of Acute Myocardial Infarction: A Systematic Review of the Literature. Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine, 20(3), 155-162. https://doi.org/10.1097/HPC.0000000000000256

Background: Despite the availability of tests to diagnose acute myocardial infarction (AMI), cases are still missed. Methods: We systematically reviewed the literature to determine how missed AMI has been defined, the reported rates of misdiagnosed A... Read More about Misdiagnosis of Acute Myocardial Infarction: A Systematic Review of the Literature.

Survey of young people in one region of the UK on accessing COVID-19 information (SOCIAL) (2021)
Journal Article
Lawton, O. G., Lawton, S. A., Dikomitis, L., Protheroe, J., Smith, J., & Mallen, C. (2021). Survey of young people in one region of the UK on accessing COVID-19 information (SOCIAL). BMJ Paediatrics Open, e000942 - e000942. https://doi.org/10.1136/bmjpo-2020-000942

COVID-19 has significantly impacted young people’s lives yet little is known about the COVID-19 related sources of information they access. We performed a cross-sectional survey of pupils (11–16 years) in North Staffordshire, UK. 408 (23%) pupils res... Read More about Survey of young people in one region of the UK on accessing COVID-19 information (SOCIAL).

Acute Myocardial Infarction in Autoimmune Rheumatological Disease: A Nationwide Analysis of Clinical outcomes and Predictors of Management Strategy (2021)
Journal Article
Mamas, Clarson, Roddy, Mallen, & Helliwell. (2021). Acute Myocardial Infarction in Autoimmune Rheumatological Disease: A Nationwide Analysis of Clinical outcomes and Predictors of Management Strategy. Mayo Clinic Proceedings, 388-399. https://doi.org/10.1016/j.mayocp.2020.04.044

Objectives: The present study sought to examine national-level differences in management strategies and outcomes in patients with autoimmune rheumatic disease (AIRD) with acute myocardial infarction (AMI) between 2004 and 2014. Methods: All AMI hos... Read More about Acute Myocardial Infarction in Autoimmune Rheumatological Disease: A Nationwide Analysis of Clinical outcomes and Predictors of Management Strategy.

Rheumatic Conditions as Risk Factors for Self-Harm: A Retrospective Cohort Study (2021)
Journal Article
Prior, J. A., Paskins, Z., Whittle, R., Abdul-Sultan, A., Chew-Graham, C. A., Muller, S., …Mallen, C. D. (2021). Rheumatic Conditions as Risk Factors for Self-Harm: A Retrospective Cohort Study. Arthritis Care and Research, 73(1), 130-137. https://doi.org/10.1002/acr.24345

Objective To examine the risk of self-harm in rheumatological conditions Methods Retrospective cohort study using data from the Clinical Practice Research Datalink. Patients with ankylosing spondylitis, fibromyalgia, osteoarthritis or rheumatoid arth... Read More about Rheumatic Conditions as Risk Factors for Self-Harm: A Retrospective Cohort Study.

Experience of implementing and delivering group consultations in UK general practice: a qualitative study (2021)
Journal Article
Swaithes, L., Paskins, Z., Duffy, H., Evans, N., Mallen, C., Dziedzic, K., & Finney, A. (2021). Experience of implementing and delivering group consultations in UK general practice: a qualitative study. British Journal of General Practice (BJGP), 71(707), E413-E422. https://doi.org/10.3399/BJGP.2020.0856

BACKGROUND: Group consultations are a relatively new concept in UK primary care and are a suggested solution to current workload pressures in general practice. Little is known about the experience of implementing and delivering this approach from sta... Read More about Experience of implementing and delivering group consultations in UK general practice: a qualitative study.

General practitioners' deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries (2021)
Journal Article
Mallen. (2021). General practitioners' deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries. BMC Geriatrics, https://doi.org/10.1186/s12877-020-01953-6

BACKGROUND: General practitioners (GPs) should regularly review patients' medications and, if necessary, deprescribe, as inappropriate polypharmacy may harm patients' health. However, deprescribing can be challenging for physicians. This study invest... Read More about General practitioners' deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries.