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All Outputs (58)

what factors require consideration when individualising exercise interventions for people with osteoarthritis? Consensus of experts using a delphi methodology (2023)
Presentation / Conference
Yaseen, K., Zhang, W., Doherty, M., Abhishek, A., Jamtvedt, G., Martinez, M., …Hall, M. (2023, March). what factors require consideration when individualising exercise interventions for people with osteoarthritis? Consensus of experts using a delphi methodology. Poster presented at 2023 OARSI World Congress on Osteoarthritis, Sheraton Denver Downtown Hotel, Denver, USA

Is Vaccination Against Covid-19 Associated with Autoimmune Rheumatic Disease Flare? Self-controlled Case Series Analysis Using Data from the Clinical Practice Research Datalink (Aurum) (2022)
Presentation / Conference
Nakafero, G., Grainge, M. J., Card, T., Mallen, C., Nguyen van Tam, J. S., Williams, H. C., & Abhishek, A. (2022, November). Is Vaccination Against Covid-19 Associated with Autoimmune Rheumatic Disease Flare? Self-controlled Case Series Analysis Using Data from the Clinical Practice Research Datalink (Aurum). Paper presented at ACR Convergence 2022, Philadelphia, PA, USA

Background/Purpose: It is unclear whether autoimmune rheumatic disease (AIRD) flares are associated with the recent prior Covid-19 vaccination, and whether the association was influenced by vaccine modality and prior Covid-19 infection. The objective... Read More about Is Vaccination Against Covid-19 Associated with Autoimmune Rheumatic Disease Flare? Self-controlled Case Series Analysis Using Data from the Clinical Practice Research Datalink (Aurum).

Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study (2022)
Presentation / Conference
Rathod-Mistry, T., Roddy, E., Jordan, K., Mallen, C., & Blagojevic-Bucknall, M. (2022, August). Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study

Background: Allopurinol is intended to be taken for life in the treatment of gout. In UK primary care, treatment is suboptimal with up to 30% of indicated patients being treated within five years of diagnosis and once prescribed allopurinol, treatmen... Read More about Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study.

Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM) (2022)
Presentation / Conference
Mason, K., Bailey, J., Heron, N., Marshall, M., Achana, F., Chen, Y., …Jordan, K. (2022, July). Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM). Paper presented at SAPC ASM 2022 - UCLan 50th Annual Scientific Meeting, University of Central Lancashire, UK

Background: Patients with painful musculoskeletal conditions have an increased risk of developing cancer, but less is known about whether this impacts on the longer-term cancer prognosis. This study aims to determine whether patients with painful mus... Read More about Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM).

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K. P., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Paper presented at 2021 SAPC North, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mallen, Mason, Frisher, Mamas, Jordan, Marshall, …White. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Presented at SAPC North 2021, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Metformin use and the risk of total knee replacement among diabetic patients in primary care (2021)
Presentation / Conference
Sit, R., Lai, F., Yip, B., Hunter, D., Rabago, D., Mallen, C., & Wong, S. (2021, April). Metformin use and the risk of total knee replacement among diabetic patients in primary care. Presented at Virtual 2021 OARSI World Congress on Osteoarthritis, Virtual

Purpose: Metformin, apart from its glucose lowering and weight reduction effects, has recently been shown to modulate meta-inflammation, an important pathogenesis in knee osteoarthritis (OA). We aim to study the association between regular metformin... Read More about Metformin use and the risk of total knee replacement among diabetic patients in primary care.

Examining the impact of an innovative online qualitative study (netnography) in developing a clinical pharmacist-led review for persistent pain patients in primary care (PROMPPT study) (2020)
Presentation / Conference
Woodcock, C., Ashworth, J., Cornwall, N., Harrisson, S. A., Buttery, A., Jinks, C., …Dikomitis, L. (2020, June). Examining the impact of an innovative online qualitative study (netnography) in developing a clinical pharmacist-led review for persistent pain patients in primary care (PROMPPT study). Presented at ASM 2020 (CANCELLED), Chicago, Illinois

FRI0610-HPR Β-ADRENORECEPTOR BLOCKING DRUGS ASSOCIATE WITH LOWER RISK OF KNEE OSTEOARTHRITIS AND KNEE PAIN CONSULTATIONS IN PRIMARY CARE: A PROPENSITY SCORE MATCHED COHORT STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK. (2020)
Presentation / Conference
Nakafero, G., Grainge, M., Valdes, A., Townsend, N., Mallen, C., Zhang, W., …Abhishek, A. (2020, June). FRI0610-HPR Β-ADRENORECEPTOR BLOCKING DRUGS ASSOCIATE WITH LOWER RISK OF KNEE OSTEOARTHRITIS AND KNEE PAIN CONSULTATIONS IN PRIMARY CARE: A PROPENSITY SCORE MATCHED COHORT STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK

Background: The pharmacologic management of OA is centred around optimising pain control but first-line analgesics only have modest efficacy1. Findings from several studies suggest that β-adrenoreceptor blocking drugs (β-blockers) have anti-nocicepti... Read More about FRI0610-HPR Β-ADRENORECEPTOR BLOCKING DRUGS ASSOCIATE WITH LOWER RISK OF KNEE OSTEOARTHRITIS AND KNEE PAIN CONSULTATIONS IN PRIMARY CARE: A PROPENSITY SCORE MATCHED COHORT STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK..

The relationship between obesity and outcomes in patients with polymyalgia rheumatica (2020)
Presentation / Conference
Scott, I. C., Bajpai, R., Mallen, C., Muller, S., Helliwell, T., & Hider, S. (2020, April). The relationship between obesity and outcomes in patients with polymyalgia rheumatica. Presented at British Society for Rheumatology Annual Conference 2020, Scottish Event Campus (SEC), Scotland, UK

Background Obesity predisposes to a pro-inflammatory state. Studies have reported worse clinical outcomes in patients with inflammatory arthritis who are obese. The relationship between obesity and outcomes in patients with polymyalgia rheumatica (P... Read More about The relationship between obesity and outcomes in patients with polymyalgia rheumatica.

P148 Gastrointestinal symptoms and proton pump inhibitor use in patients with polymyalgia rheumatica: results from the PMR Cohort study (2020)
Presentation / Conference
Feddah, H., Muller, S., Hider, S., Hay, C., & Mallen, C. (2020, April). P148 Gastrointestinal symptoms and proton pump inhibitor use in patients with polymyalgia rheumatica: results from the PMR Cohort study. Poster presented at British Society for Rheumatology Annual Conference 2020, - Cancelled -

Background Polymyalgia Rheumatica (PMR) is a common disorder of older adults, characterised by pain and stiffness in the shoulders and hips. PMR is one of the commonest indications for long-term glucocorticoid use. Because of the well-recognised sid... Read More about P148 Gastrointestinal symptoms and proton pump inhibitor use in patients with polymyalgia rheumatica: results from the PMR Cohort study.

O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT) (2020)
Presentation / Conference
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., …Roddy, E. (2020, April). O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT). Presented at British Society for Rheumatology Annual Conference 2020, Glasgow, Scotland, UK

Background Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited. The HIT trial compared the clinical and cost-effectiveness of an ultrasound-guided intra-articular hip injection (USGI) of 4... Read More about O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT).

Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT) (2019)
Presentation / Conference
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., …Roddy, E. (2019, November). Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT). Paper presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT).

DIabetes Severity SCOre (DISSCO) improves hospitalisation and mortality prediction: model development and validation in 139,626 people with type 2 diabetes (2019)
Presentation / Conference
Zghebi, S., Mamas, M., Ashcroft, D. M., Salisbury, C., Mallen, C., Chew-Graham, C., …Kontopantelis, E. (2019, September). DIabetes Severity SCOre (DISSCO) improves hospitalisation and mortality prediction: model development and validation in 139,626 people with type 2 diabetes. Paper presented at 55th EASD Annual Meeting of the European Association for the Study of Diabetes, Barcelona, Spain

A systematic review of measures using clinical data for assessing the severity of Type 2 diabetes (2019)
Presentation / Conference
Zghebi, S., Panagioti, M., Rutter, M., Ashcroft, D., van Marwijk, H., Salisbury, C., …Kontopantelis, E. (2019, March). A systematic review of measures using clinical data for assessing the severity of Type 2 diabetes. Poster presented at Diabetes UK Professional Conference 2019, ACC Liverpool, Liverpool, UK

Background/Aims: The assessment of disease severity in people with diabetes enables identification of patients in need for intensive and targeted therapies, and could help optimise the allocation of healthcare resources. We aimed to identify and appr... Read More about A systematic review of measures using clinical data for assessing the severity of Type 2 diabetes.

Inactivated Influenza Vaccine Prevents Respiratory Infections and Improves All-Cause and Cause-Specific Mortality in Immunosuppressed People with Autoimmune Rheumatic Diseases: Propensity Score Adjusted Cohort Study Using Data from Clinical Practice Research Datalink (2018)
Presentation / Conference
Nakafero, G., Grainge, M., Myles, P., Mallen, C., Zhang, W., Doherty, M., …Abhishek, A. (2018, October). Inactivated Influenza Vaccine Prevents Respiratory Infections and Improves All-Cause and Cause-Specific Mortality in Immunosuppressed People with Autoimmune Rheumatic Diseases: Propensity Score Adjusted Cohort Study Using Data from Clinical Practice Research Datalink. Paper presented at 2018 ACR/ARHP Annual Meeting, Chicago, IL, USA

Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study (2018)
Presentation / Conference
Crowley, L., Abdul Sultan, A., Roddy, E., Mallen, C., Protheroe, J., & Clarson, L. (2018, October). Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study. Poster presented at 2018 ACR/ARHP Annual Meeting

Background/Purpose: Evidence is conflicting concerning dementia risk in gout patients, with hyperuricaemia proposed to exert a neuroprotective effect. Serum urate (sUA) targets guiding urate-lowering therapies (ULT) are poorly evidenced-based and th... Read More about Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study.

PREDICTORS AND TEMPORAL TREND OF SEASONAL INFLUENZA VACCINATION IN AUTO-IMMUNE RHEUMATIC DISEASES IN THE UK: A NATIONWIDE PROSPECTIVE COHORT STUDY (2018)
Presentation / Conference
Nakafero, G., Grainge, M., Myles, P., Mallen, C., Zhang, W., Doherty, M., …Abhishek, A. (2018, June). PREDICTORS AND TEMPORAL TREND OF SEASONAL INFLUENZA VACCINATION IN AUTO-IMMUNE RHEUMATIC DISEASES IN THE UK: A NATIONWIDE PROSPECTIVE COHORT STUDY. Poster presented at Annual European Congress of Rheumatology

Background: Autoimmune rheumatic diseases (AIRDs) are associated with an increased risk of influenza and its complications which may be compounded by the use of potent disease modifying anti-rheumatic drugs (DMARDs). In the United Kingdom, seasonal i... Read More about PREDICTORS AND TEMPORAL TREND OF SEASONAL INFLUENZA VACCINATION IN AUTO-IMMUNE RHEUMATIC DISEASES IN THE UK: A NATIONWIDE PROSPECTIVE COHORT STUDY.

AB0212 Diagnostic delay for rheumatoid arthritis: a systematic review (2018)
Presentation / Conference
Hay, C., Prior, J., Scott, I., Raza, K., Hider, S., & Mallen, C. (2018, June). AB0212 Diagnostic delay for rheumatoid arthritis: a systematic review. Paper presented at Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, Netherlands

Background Rheumatoid arthritis (RA) is a common inflammatory condition, affecting 1% of the population and causing pain, stiffness and swelling, leading to significant disability and loss of function[.1 Delays in the diagnosis and treatment of RA ca... Read More about AB0212 Diagnostic delay for rheumatoid arthritis: a systematic review.