All Outputs (58)

The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations (2021)
Journal Article
Mallen, C., Khunti, K., & Mughal, F. (2021). The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations. Journal of Family Medicine and Primary Care, 4345-4349. https://doi.org/10.4103/jfmpc.jfmpc_756_21

COVID-19 has changed health systems and services. In this commentary, we outline the impact COVID-19 has had on the delivery of primary health care, and on primary care teams, and describe the NHS response. We highlight the challenges of managing lon... Read More about The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations.

Misdiagnosis of aortic dissection: A systematic review of the literature (2021)
Journal Article
Mallen. (2021). Misdiagnosis of aortic dissection: A systematic review of the literature. American Journal of Emergency Medicine, https://doi.org/10.1016/j.ajem.2021.11.047

Background Aortic dissection is a rare but potentially catastrophic condition. Misdiagnosis of aortic dissection is not uncommon as symptoms can overlap with other diagnoses. Objective We conducted a systematic review to better understand the fa... Read More about Misdiagnosis of aortic dissection: A systematic review of the literature.

An evaluation of the use of investigations in a nurse-led rapid access chest pain clinic (2021)
Journal Article
Mallen. (2021). An evaluation of the use of investigations in a nurse-led rapid access chest pain clinic. British Journal of Cardiac Nursing, 1 - 14. https://doi.org/10.12968/bjca.2021.0084

Background/Aims Chest pain is a common symptom, but its presentation and cause varies widely, making diagnosis a challenge. This study describes the authors' experience of a nurse-led rapid access chest pain clinic, and associated use of investigatio... Read More about An evaluation of the use of investigations in a nurse-led rapid access chest pain clinic.

Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients (2021)
Journal Article
Mallen, Wells, I., T Zemedikun, D., Simons, G., J Stack, R., D Mallen, C., …Falahee, M. (2022). Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients. Rheumatology, 61(8), https://doi.org/10.1093/rheumatology/keab890

OBJECTIVES: There is increasing interest in prediction and prevention of rheumatoid arthritis (RA). It is important to understand the views of those at risk to inform the development of effective approaches. First-degree relatives (FDRs) of RA patien... Read More about Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients.

Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study (2021)
Journal Article
Paskins, Z., Sokhal, B. S., Hider, S. L., Mallen, C. D., & Muller, S. (2021). Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study. Rheumatology Advances in Practice, Article rkab094. https://doi.org/10.1093/rap/rkab094

OBJECTIVES: PMR is a common indication for long-term glucocorticoid treatment, leading to an increased risk of osteoporosis and fragility fractures. Guidelines recommend calcium and vitamin D for all patients, in addition to anti-resorptive agents fo... Read More about Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study.

Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data (2021)
Journal Article
Scott, I. C., Bailey, J., White, C. R., Mallen, C., & Muller, S. (2022). Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data. Rheumatology, 61(8), 3201–3211. https://doi.org/10.1093/rheumatology/keab870

OBJECTIVES: International data suggest inflammatory arthritis (IA) pain management frequently involves opioid prescribing, despite little evidence of efficacy, and potential harms. We evaluated analgesia prescribing in English National Health Service... Read More about Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data.

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mallen, Mason, Frisher, Mamas, Jordan, Marshall, …White. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Presented at SAPC North 2021, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K. P., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Paper presented at 2021 SAPC North, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood-tests during long-term treatment: cohort study using data from Clinical Practice Research Datalink Gold and Aurum. (2021)
Journal Article
Mallen. (2021). Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood-tests during long-term treatment: cohort study using data from Clinical Practice Research Datalink Gold and Aurum. Rheumatology, https://doi.org/10.1093/rheumatology/keab790

OBJECTIVE: To develop and validate a prognostic model for leflunomide discontinuation with abnormal blood-test results. METHODS: Data from CPRD Gold and Aurum were used for model development and external validation respectively. Participants prescrib... Read More about Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood-tests during long-term treatment: cohort study using data from Clinical Practice Research Datalink Gold and Aurum..

Readmission after index hospital discharge among patients with COVID-19: Protocol for a systematic review and meta-analysis (2021)
Journal Article
AlSayegh, A., Gassan, A. A., Bajpai, R. C., Muller, S., Welsh, V., Kwok, C. S., & Mallen, C. D. (2021). Readmission after index hospital discharge among patients with COVID-19: Protocol for a systematic review and meta-analysis. Health Science Reports, 4(4), Article ARTN e417. https://doi.org/10.1002/hsr2.417

Background and Aims: Hospital readmissions among COVID-19 patients have increased the load on the healthcare systems and added more pressure to hospital capacity. This affects the ability to accommodate newly diagnosed COVID-19 patients and other non... Read More about Readmission after index hospital discharge among patients with COVID-19: Protocol for a systematic review and meta-analysis.

What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study (2021)
Journal Article
Weddell, J., Hider, S., Mallen, C., & Muller, S. (2022). What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study. Rheumatology International, 285-290. https://doi.org/10.1007/s00296-021-05036-6

Polymyalgia rheumatica (PMR) is common. The mainstay of treatment, glucocorticoids, are associated with significant adverse effects and many patients remain on high doses for a number of years. Little is known about the use of other, non-pharmacologi... Read More about What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study.

Predicting pain and function outcomes in people consulting with shoulder pain: the PANDA-S clinical cohort and qualitative study protocol (2021)
Journal Article
Wynne-Jones, G., Myers, H., Hall, A., Littlewood, C., Hennings, S., Saunders, B., …van der Windt, D. (2021). Predicting pain and function outcomes in people consulting with shoulder pain: the PANDA-S clinical cohort and qualitative study protocol. BMJ Open, 11(9), Article e052758. https://doi.org/10.1136/bmjopen-2021-052758

INTRODUCTION: People presenting with shoulder pain considered to be of musculoskeletal origin is common in primary care but diagnosing the cause of the pain is contentious, leading to uncertainty in management. To inform optimal primary care for pati... Read More about Predicting pain and function outcomes in people consulting with shoulder pain: the PANDA-S clinical cohort and qualitative study protocol.

Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial. (2021)
Journal Article
Healey, E. L., Mallen, C. D., Chew-Graham, C. A., Nicholls, E., Lewis, M., Lawton, S. A., …Jinks, C. (2022). Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial. Family Practice, 39(4), 592–602. https://doi.org/10.1093/fampra/cmab113

Background: Multimorbidity is increasingly the norm; however, primary care remains focused on single diseases. Osteoarthritis, anxiety, and depression are frequently comorbid with other long-term conditions (LTCs), but rarely prioritized by clinician... Read More about Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial..

Smoking cessation after acute coronary syndrome: A systematic review and meta-analysis. (2021)
Journal Article
Mallen. (2021). Smoking cessation after acute coronary syndrome: A systematic review and meta-analysis. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.14894

BACKGROUND: Smoking cessation is an effective secondary prevention measure after acute coronary syndrome (ACS). We conducted a systematic review with the aim to better understand which patients have a greater propensity to quit smoking, and the risk... Read More about Smoking cessation after acute coronary syndrome: A systematic review and meta-analysis..

The patient pathway review: A new method of evaluating clinical practices to understand the complexities of real-world care. (2021)
Journal Article
Kwok, C. S., Muntean, E., & Mallen, C. (2021). The patient pathway review: A new method of evaluating clinical practices to understand the complexities of real-world care. Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine, 20(4), 213-219. https://doi.org/10.1097/HPC.0000000000000267

Healthcare research has contributed to the good patient care that is delivered today. With the perpetual demand for higher quality, cost-effective care, the current approaches in research could be improved to answer important research questions relat... Read More about The patient pathway review: A new method of evaluating clinical practices to understand the complexities of real-world care..

Vertebral fracture as a risk factor for self-harm: A retrospective cohort study (2021)
Journal Article
Prior, J. A., Crawford-Manning, F., Whittle, R., Abdul-Sultan, A., Chew-Graham, C. A., Muller, S., …Paskins, Z. (2021). Vertebral fracture as a risk factor for self-harm: A retrospective cohort study. BMC Musculoskeletal Disorders, 22, Article 757. https://doi.org/10.1186/s12891-021-04631-9

Abstract Background The prevention of self-harm is an international public health priority. It is vital to identify at-risk populations, particularly as self-harm is a risk factor for suicide. This study aims to examine the risk of self-harm in peopl... Read More about Vertebral fracture as a risk factor for self-harm: A retrospective cohort study.

Social Work and Social Care: Mapping Workforce Engagement, Relevance, Experience and Interest in Research (2021)
Journal Article
Lambley-Burke, R., Wakefield, J., Lavender, S., Nixon, K., Hornby, S., Dobel-Ober, D., …Mallen, C. (2022). Social Work and Social Care: Mapping Workforce Engagement, Relevance, Experience and Interest in Research. British Journal of Social Work, 52(4), https://doi.org/10.1093/bjsw/bcab169

Evidence-based practice (EBP) has been promoted within social work/social care, with emerging evidence of benefit to practitioners and service users. Advocates argue that EBP enables practitioners to have the skills to interpret and evaluate evidence... Read More about Social Work and Social Care: Mapping Workforce Engagement, Relevance, Experience and Interest in Research.

Reply (2021)
Journal Article
Hay, C. A., Mallen, C. D., Belcher, J., Roddy, E., & Prior, J. A. (2022). Reply. Arthritis Care and Research, 74(1), 161-162. https://doi.org/10.1002/acr.24777

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