All Outputs (5)

IS INTRAVENOUS ASPIRIN SAFE FOR EMERGENT STENTING IN THROMBOLYSED PATIENTS TREATED BY MECHANICAL THROMBECTOMY? (2021)
Journal Article
Ingleton, A., Raseta, M., & Roffe, C. (2021). IS INTRAVENOUS ASPIRIN SAFE FOR EMERGENT STENTING IN THROMBOLYSED PATIENTS TREATED BY MECHANICAL THROMBECTOMY?. International Journal of Stroke, 16(3),

Introduction: Intraoperative stenting is used during mechanical thrombectomy (MT) to manage severe stenosis or dissection. Antiplatelet agents are required intraoperatively to maintain patency of the stent. However, antiplatelets are contraindicated... Read More about IS INTRAVENOUS ASPIRIN SAFE FOR EMERGENT STENTING IN THROMBOLYSED PATIENTS TREATED BY MECHANICAL THROMBECTOMY?.

THE METOCLOPRAMIDE FOR AVOIDING PNEUMONIA AFTER STROKE (MAPS-2) TRIAL: A SINGLE-BLIND RCT OF METOCLOPRAMIDE FOR THE PREVENTION OF PNEUMONIA IN PATIENTS WITH DYSPHAGIA AFTER STROKE (2021)
Presentation / Conference
Roffe, C., Bath, P., Warusevitane, A., Smith, C., Dixit, A., Sprigg, N., …Ogollah, R. (2021, November). THE METOCLOPRAMIDE FOR AVOIDING PNEUMONIA AFTER STROKE (MAPS-2) TRIAL: A SINGLE-BLIND RCT OF METOCLOPRAMIDE FOR THE PREVENTION OF PNEUMONIA IN PATIENTS WITH DYSPHAGIA AFTER STROKE. Presented at UK Stroke Forum 2021, Virtual

Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study (2021)
Journal Article
Perry, R. J., Tamborska, A., Singh, B., Craven, B., Marigold, R., Arthur-Farraj, P., …Zambreanu, L. (2021). Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study. The Lancet, 398(10306), 1147-1156. https://doi.org/10.1016/s0140-6736%2821%2901608-1

Background A new syndrome of vaccine-induced immune thrombotic thrombocytopenia (VITT) has emerged as a rare side-effect of vaccination against COVID-19. Cerebral venous thrombosis is the most common manifestation of this syndrome but, to our knowle... Read More about Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study.

Oxygen desaturation and adverse outcomes in acute stroke: secondary analysis of the HeadPoST study (2021)
Journal Article
Roffe. (2021). Oxygen desaturation and adverse outcomes in acute stroke: secondary analysis of the HeadPoST study. Clinical Neurology and Neurosurgery, 106796 - 106796. https://doi.org/10.1016/j.clineuro.2021.106796

Objective: Uncertainty exists over the prognostic significance of low arterial oxygen saturation (SaO(2)) in acute stroke. We aimed to determine the strength of association of SaO(2) and adverse outcomes among participants of the international Head P... Read More about Oxygen desaturation and adverse outcomes in acute stroke: secondary analysis of the HeadPoST study.

Outcomes in Antiplatelet‐Associated Intracerebral Hemorrhage in the TICH‐2 Randomized Controlled Trial (2021)
Journal Article
Law, Z. K., Desborough, M., Roberts, I., Al‐Shahi Salman, R., England, T. J., Werring, D. J., …Sprigg, N. (2021). Outcomes in Antiplatelet‐Associated Intracerebral Hemorrhage in the TICH‐2 Randomized Controlled Trial. Journal of the American Heart Association, 10(5), https://doi.org/10.1161/jaha.120.019130

BackgroundAntiplatelet therapy increases the risk of hematoma expansion in intracerebral hemorrhage (ICH) while the effect on functional outcome is uncertain.Methods and ResultsThis is an exploratory analysis of the TICH‐2 (Tranexamic Acid in Intrace... Read More about Outcomes in Antiplatelet‐Associated Intracerebral Hemorrhage in the TICH‐2 Randomized Controlled Trial.