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Prognostic Value of Time in Blood Pressure Target Range Among Patients With Heart Failure (2022)
Journal Article
Chen, K., Li, C., Cornelius, V., Yu, D., Wang, Q., Shi, R., …Jiang, Z. (2022). Prognostic Value of Time in Blood Pressure Target Range Among Patients With Heart Failure. JACC: Heart Failure, 10(6), 369-379. https://doi.org/10.1016/j.jchf.2022.01.010

BACKGROUND Blood pressure (BP) is a continuous and dynamic measure. However, standard BP control metrics may not reflect the variability in BP over time. OBJECTIVES This study assessed the prognostic value of time in BP target range among hypertensiv... Read More about Prognostic Value of Time in Blood Pressure Target Range Among Patients With Heart Failure.

Opioid use prior to total knee replacement: comparative analysis of trends in England and Sweden (2022)
Journal Article
Yu, D., Hellberg, C., Appleyard, T., Dell'Isola, A., Thomas, G. E. R., Turkiewicz, A., …Peat, G. (2022). Opioid use prior to total knee replacement: comparative analysis of trends in England and Sweden. Osteoarthritis and Cartilage, 30(6), 815-822. https://doi.org/10.1016/j.joca.2022.02.621

Objectives To describe and compare trends in the frequency of opioid prescribing/dispensing in English and Swedish patients with osteoarthritis prior to total knee replacement (TKR). Methods 49,043 patients from an English national database (Clinical... Read More about Opioid use prior to total knee replacement: comparative analysis of trends in England and Sweden.

The impact of nursing staff education on diabetes inpatient glucose management: a pilot cluster randomised controlled trial (2022)
Journal Article
Piya, M., Zarora, R., Yu, D., Fletcher, T., Myint, K., & Simmons, D. (2022). The impact of nursing staff education on diabetes inpatient glucose management: a pilot cluster randomised controlled trial. BMC Endocrine Disorders, 22, Article 61. https://doi.org/10.1186/s12902-022-00975-y

Background: An increasing number of patients in hospital have diabetes, with most of them cared for by non-specialist staff. The effect of diabetes education for staff on patient outcomes, as well as the most effective method of staff education is un... Read More about The impact of nursing staff education on diabetes inpatient glucose management: a pilot cluster randomised controlled trial.

Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness (2022)
Journal Article
Peat, G., Jordan, K., Wilkie, R., Corp, N., Van Der Windt, D., Yu, D., …Ali, N. (2022). Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness. Journal of Public Health, 44(3), e376–e387. https://doi.org/10.1093/pubmed/fdac014

Background It is unclear whether seven interventions recommended by Public Health England for preventing and managing common musculoskeletal conditions reduce or widen health inequalities in adults with musculoskeletal conditions. Methods We used cit... Read More about Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness.

Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases (2022)
Journal Article
Yu, D., Missen, M., P Jordan, K., Edwards, J., Bailey, J., Wilkie, R., …Peat, G. (2022). Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases. Clinical Epidemiology, 14, 179-189. https://doi.org/10.2147/CLEP.S337323

Purpose: To compare estimates of annual person-consulting incidence and prevalence of low back pain (LBP) and osteoarthritis for two national English electronic health record databases (Clinical Practice Research Datalink (CPRD) Aurum and CPRD GOLD).... Read More about Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases.

Ethnic Differences in Cancer Rates Among Adults With Type 2 Diabetes in New Zealand From 1994 to 2018 (2022)
Journal Article
Yu, D., Wang, Z., Cai, Y., McBride, K., Osuagwu, U. L., Pickering, K., …Simmons, D. (2022). Ethnic Differences in Cancer Rates Among Adults With Type 2 Diabetes in New Zealand From 1994 to 2018. Jama Network Open, 5(2), Article e2147171. https://doi.org/10.1001/jamanetworkopen.2021.47171

Importance People with type 2 diabetes have greater risk for some site-specific cancers, and risks of cancers differ among racial and ethnic groups in the general population of Aotearoa New Zealand. The extent of ethnic disparities in cancer risks a... Read More about Ethnic Differences in Cancer Rates Among Adults With Type 2 Diabetes in New Zealand From 1994 to 2018.

Geographical distribution of trace elements (selenium, zinc, iron, copper) and case fatality rate of COVID-19: a national analysis across conterminous USA (2022)
Journal Article
Chen, Y., Ma, Z., Yu, D., Jiang, Z., Wang, B., & Yuan, L. (2022). Geographical distribution of trace elements (selenium, zinc, iron, copper) and case fatality rate of COVID-19: a national analysis across conterminous USA. Environmental Geochemistry and Health, 44, 4423–4436. https://doi.org/10.1007/s10653-022-01204-0

Severe outcome particularly death is the largest burden of COVID-19. Clinical observations showed preliminary data that deficiency in certain trace elements, essential for the normal activity of immune system, may be associated with worse COVID-19 ou... Read More about Geographical distribution of trace elements (selenium, zinc, iron, copper) and case fatality rate of COVID-19: a national analysis across conterminous USA.

1263 Does Multimorbidity Influence the Likelihood of Receiving A Total Hip Replacement for Osteoarthritis? (2021)
Journal Article
Ferguson, R., Prieto-Alhambra, D., Peat, G., Jordan, K., Valderas, J., Yu, D., …Silman, A. (2021). 1263 Does Multimorbidity Influence the Likelihood of Receiving A Total Hip Replacement for Osteoarthritis?. British Journal of Surgery, 108(Supplement_6), https://doi.org/10.1093/bjs/znab259.1038

Introduction Limited data are available on the influence of multimorbidity on the outcomes of total hip replacement for patients with hip osteoarthritis. Thus, patients with multimorbidity and their clinicians across the UK are making decisions on wh... Read More about 1263 Does Multimorbidity Influence the Likelihood of Receiving A Total Hip Replacement for Osteoarthritis?.

1279 Does Multimorbidity Influence the Outcomes of Total Hip Replacement for Osteoarthritis? (2021)
Journal Article
Ferguson, R., Prieto-Alhambra, D., Peat, G., Jordan, K., Valderas, J., Yu, D., …Silman, A. (2021). 1279 Does Multimorbidity Influence the Outcomes of Total Hip Replacement for Osteoarthritis?. British Journal of Surgery, 108(Supplement_6), https://doi.org/10.1093/bjs/znab259.1040

Introduction Limited data are available on the influence of multimorbidity on the outcomes of total hip replacement for patients with hip osteoarthritis, including the rate of complications and degree of functional benefit. The aim of this study was... Read More about 1279 Does Multimorbidity Influence the Outcomes of Total Hip Replacement for Osteoarthritis?.

Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies. (2021)
Journal Article
Huang, X., Wilkie, R., Mamas, M., & Yu, D. (2021). Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies. Journal of Diabetes and Clinical Research, 3(3), https://doi.org/10.33696/diabetes.3.042

Background: People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opportunities... Read More about Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies..

Does pre-existing morbidity influences risks and benefits of total hip replacement for osteoarthritis: a prospective study of 6682 patients from linked national datasets in England (2021)
Journal Article
Ferguson, R., Prieto-Alhambra, D., Peat, G., Delmestri, A., P Jordan, K., Y Strauss, V., …Silman, A. (2021). Does pre-existing morbidity influences risks and benefits of total hip replacement for osteoarthritis: a prospective study of 6682 patients from linked national datasets in England. BMJ Open, e046712 - ?. https://doi.org/10.1136/bmjopen-2020-046712

Total hip arthroplasty (THA) surgery for elderly people with multimorbidity increases the risk of serious health hazards including mortality. Whether such background morbidity reduces the clinical benefit is less clear. OBJECTIVE: To evaluate how pre... Read More about Does pre-existing morbidity influences risks and benefits of total hip replacement for osteoarthritis: a prospective study of 6682 patients from linked national datasets in England.

Influence of pre-existing multimorbidity on receiving a hip arthroplasty: cohort study of 28 025 elderly subjects from UK primary care (2021)
Journal Article
Ferguson, R., Prieto-Alhambra, D., Peat, G., Delmestri, A., Jordan, K. P., Strauss, V. Y., …Silman, A. (2021). Influence of pre-existing multimorbidity on receiving a hip arthroplasty: cohort study of 28 025 elderly subjects from UK primary care. BMJ Open, 11(9), Article e046713. https://doi.org/10.1136/bmjopen-2020-046713

The median age for total hip arthroplasty (THA) is over 70 years with the corollary that many individuals have multiple multimorbidities. Despite the predicted improvement in quality of life, THA might be denied even to those with low levels of multi... Read More about Influence of pre-existing multimorbidity on receiving a hip arthroplasty: cohort study of 28 025 elderly subjects from UK primary care.

496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis (2021)
Journal Article
Huang, M., Yu, D., Wilkie, R., & Mamas, M. (2021). 496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis. International Journal of Epidemiology, i105 - i105. https://doi.org/10.1093/ije/dyab168.295

Abstract Background Osteoarthritis (OA) has a major impact on the global burden of disease and is associated with poorer cardiovascular disease (CVD) outcomes. However it’s unclear whether people with OA have higher long-term (10-year) CVD risk comp... Read More about 496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis.

338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study (2021)
Journal Article
Yu, D., Jordan, K., Bailey, J., Peat, G., & Wilkie, R. (2021). 338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study. International Journal of Epidemiology, 50(Supplement_1), https://doi.org/10.1093/ije/dyab168.739

Background Patient Reported Outcome Measures (PROM) collected in surveys allow understanding of the health at the population-level. We aimed to test the feasibility of estimating health status as measured by PROMs through ecological prediction model... Read More about 338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study.

Remnant cholesterol and cardiovascular mortality in patients with type 2 diabetes and incident diabetic nephropathy (2021)
Journal Article
Qu, B., Zhang, X., Yu, D., Wang, Z., Cai, Y., Ma, S., …Simmons, D. (2021). Remnant cholesterol and cardiovascular mortality in patients with type 2 diabetes and incident diabetic nephropathy. Journal of Clinical Endocrinology and Metabolism, 3546-3553. https://doi.org/10.1210/clinem/dgab533

Context The association between remnant cholesterol (remnant-C) and cardiovascular mortality in patients with type 2 diabetes (T2D) and incident diabetic nephropathy remains unclear. Objective To examinie the association between remnant-C and ca... Read More about Remnant cholesterol and cardiovascular mortality in patients with type 2 diabetes and incident diabetic nephropathy.

Investigating outcome inequalities in osteoarthritis management programmes: an analysis of registry data from the good life with osteoarthritis in Denmark (GLA:D®) programme using tapered balancing (2021)
Journal Article
Peat, G., Yu, D., Grønne, D., Marshall, M., Skou, S., & Roos, E. (2021). Investigating outcome inequalities in osteoarthritis management programmes: an analysis of registry data from the good life with osteoarthritis in Denmark (GLA:D®) programme using tapered balancing. Osteoarthritis and Cartilage, 29(S1), S376. https://doi.org/10.1016/j.joca.2021.02.489

Purpose: The burden of osteoarthritis (OA) is often greater among disadvantaged people and communities, prompting calls for more attention to equity-focussed research and policy. A specific concern is whether healthcare interventions may inadvertentl... Read More about Investigating outcome inequalities in osteoarthritis management programmes: an analysis of registry data from the good life with osteoarthritis in Denmark (GLA:D®) programme using tapered balancing.

Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China (2021)
Journal Article
Lu, L., Chen, Y., Cai, Y., Chen, T., Huang, Y., Meng, H., & Yu, D. (2021). Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China. Obesity Research and Clinical Practice, 15(3), 216-220. https://doi.org/10.1016/j.orcp.2021.03.011

Background Relationship between physical activity and fasting glucose in people with abnormal glucose metabolism is not well-known. This study was to investigate dose–response association between physical activity (PAT) and fasting glucose from two... Read More about Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China.

Applicability and cost-effectiveness of the Systolic Blood Pressure Intervention Trial (SPRINT) in the Chinese population: A cost-effectiveness modeling study (2021)
Journal Article
Chen, T., Wu, Z., Wang, D., Yang, X., Yuan, X., Qin, R., …Wang, Y. (2021). Applicability and cost-effectiveness of the Systolic Blood Pressure Intervention Trial (SPRINT) in the Chinese population: A cost-effectiveness modeling study. PLoS Medicine, 18(3), https://doi.org/10.1371/journal.pmed.1003515

BACKGROUND: The Systolic Blood Pressure Intervention Trial (SPRINT) showed significant reductions in death and cardiovascular disease (CVD) risk with a systolic blood pressure (SBP) goal of

Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies (2021)
Journal Article
Huang, X., Wilkie, R., Mamas, M., & Yu, D. (2021). Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies. MedRxiv, https://doi.org/10.1101/2021.02.14.21251130v1

Background People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opportunities f... Read More about Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies.