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Title: Prediction of Functional Disability in Older Chinese Adults Using a Random Survival Forest Model (2024)
Working Paper
Shan, Y., Jiang, S., Yu, D., Fan, W., Gao, J., Lu, W., …Wang, C. Title: Prediction of Functional Disability in Older Chinese Adults Using a Random Survival Forest Model

Background
As life expectancy increases, so does the risk of age-related diseases and functional disability, which significantly raises the risk of all-cause mortality in older adults. Individuals with disabilities may die up to 20 years earlier tha... Read More about Title: Prediction of Functional Disability in Older Chinese Adults Using a Random Survival Forest Model.

Cancer risk following onset of type 2 diabetes in New Zealanders with impaired glucose tolerance over 25 years: a matched prospective cohort study (2024)
Journal Article
Wang, Z., Yu, D., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., …Simmons, D. (in press). Cancer risk following onset of type 2 diabetes in New Zealanders with impaired glucose tolerance over 25 years: a matched prospective cohort study. BMC Cancer, 24(1), Article 892. https://doi.org/10.1186/s12885-024-12637-4

In people with prediabetes, the link between developing type 2 diabetes (T2D) and cancer risk among those with impaired glucose tolerance (IGT) remains uncertain. We examined this association in IGT individuals from primary care in South and West Auc... Read More about Cancer risk following onset of type 2 diabetes in New Zealanders with impaired glucose tolerance over 25 years: a matched prospective cohort study.

Long-term impact of type 2 diabetes onset on dementia incidence rate among New Zealanders with impaired glucose tolerance: A tapered-matched landmark analysis over 25 years (2024)
Journal Article
Yu, D., Wang, Z., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., …Simmons, D. (2024). Long-term impact of type 2 diabetes onset on dementia incidence rate among New Zealanders with impaired glucose tolerance: A tapered-matched landmark analysis over 25 years. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, https://doi.org/10.1002/alz.13855

INTRODUCTION
We aimed to investigate the association between the onset of type 2 diabetes (T2D) and dementia incidence rates (IR) in the population with impaired glucose tolerance (IGT) identified in primary care in New Zealand (NZ) over 25 years.... Read More about Long-term impact of type 2 diabetes onset on dementia incidence rate among New Zealanders with impaired glucose tolerance: A tapered-matched landmark analysis over 25 years.

Risk of renal disease progression in young adults with type-2-diabetes (2024)
Presentation / Conference
Perera, K., Baker, J., Jayanatha, K., Pickering, K., Cutfield, R., Orr-Walker, B. J., …Simmons, D. (2024, May). Risk of renal disease progression in young adults with type-2-diabetes. Paper presented at New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting & Annual General Meeting, Te Pae Convention Centre, 188 Oxford Tce, Ōtautahi Christchurch

Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study (2024)
Journal Article
Lumley, S., Yu, D., Wilkie, R., Jordan, K. P., & Peat, G. (2024). Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study. Primary Health Care Research & Development, 25, 1-8. https://doi.org/10.1017/S1463423624000070

Background:
Chronic musculoskeletal pain and anxiety/depression are significant public health problems. We hypothesised that adults with both conditions constitute a group at especially high risk of future cardiovascular health outcomes.

Aim:
To... Read More about Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study.

Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study. (2024)
Presentation / Conference
Fisher, T., Archer, C., Bailey, J., Evans, J., Kessler, D. S., Kingstone, T., …Chew-Graham, C. (2024, March). Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study. Presented at BJGP Research & Publishing Conference, RCGP Headquarters in London, England, UK

Perinatal anxiety (PNA) occurs throughout the antenatal period or up to 1 year after childbirth, with a prevalence of 21%. To investigate if primary care records could be used to identify women at 'higher risk' of PNA. Mixed-methods approach using qu... Read More about Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study..

The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation (2024)
Journal Article
Stevenson, K., Hadley‐Barrows, T., Evans, N., Campbell, L., Southam, J., Chudyk, A., …Hill, J. C. (2024). The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation. Musculoskeletal Care, 22(1), Article e1876. https://doi.org/10.1002/msc.1876

Introduction
Globally, back pain is the leading cause of years of disability. In the United Kingdom, over 20 million people live with musculoskeletal (MSK) pain, with low back pain being one of the most common causes. National strategies promote sel... Read More about The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation.

All-cause, premature, and cardiovascular death attributable to socioeconomic and ethnic disparities among New Zealanders with type 1 diabetes 1994–2019: a multi-linked population-based cohort study (2024)
Journal Article
Yu, D., Cai, Y., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., …Simmons, D. (2024). All-cause, premature, and cardiovascular death attributable to socioeconomic and ethnic disparities among New Zealanders with type 1 diabetes 1994–2019: a multi-linked population-based cohort study. BMC Public Health, 24(1), Article 298. https://doi.org/10.1186/s12889-023-17326-8

Background
New Zealand (NZ) research into type 1 diabetes mellitus (T1DM) mortality can inform policy and future research. In this study we aimed to quantify the magnitude to which ethnicity and socioeconomic disparities influenced mortality at the... Read More about All-cause, premature, and cardiovascular death attributable to socioeconomic and ethnic disparities among New Zealanders with type 1 diabetes 1994–2019: a multi-linked population-based cohort study.

Health Inequality in Eight Adverse Outcomes Over a 25-Year Period in a Multi-Ethnic Population in New Zealand Population with Impaired Glucose Tolerance and/or Impaired Fasting Glucose: An Age-Period-Cohort Analysis (2023)
Journal Article
Wang, Z., Yu, D., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., …Simmons, D. (2023). Health Inequality in Eight Adverse Outcomes Over a 25-Year Period in a Multi-Ethnic Population in New Zealand Population with Impaired Glucose Tolerance and/or Impaired Fasting Glucose: An Age-Period-Cohort Analysis. Clinical Epidemiology, 15, 1123-1143. https://doi.org/10.2147/clep.s433714

Purpose: We aimed to examine socioeconomic inequality (SI) in cause-specific outcomes among adults with impaired glucose tolerance (IGT) and/or Impaired fasting glucose (IFG) in New Zealand (NZ) over 25 years.

Patients and Methods: A population-ba... Read More about Health Inequality in Eight Adverse Outcomes Over a 25-Year Period in a Multi-Ethnic Population in New Zealand Population with Impaired Glucose Tolerance and/or Impaired Fasting Glucose: An Age-Period-Cohort Analysis.

Applying sequence analysis to uncover ‘real-world’ clinical pathways from routinely collected data: a systematic review (2023)
Journal Article
Mathew, S., Peat, G., Parry, E., Singh Sokhal, B., & Yu, D. (2024). Applying sequence analysis to uncover ‘real-world’ clinical pathways from routinely collected data: a systematic review. Journal of Clinical Epidemiology, 111226. https://doi.org/10.1016/j.jclinepi.2023.111226

Objective

This systematic review aims to elucidate the methodological practices and reporting standards associated with sequence analysis (SA) for the identification of clinical pathways in real-world scenarios, using routinely collected data.
St... Read More about Applying sequence analysis to uncover ‘real-world’ clinical pathways from routinely collected data: a systematic review.

Association Between Onset of Type 2 Diabetes and Risk of Atrial Fibrillation in New Zealanders With Impaired Glucose Tolerance Over 25 Years (2023)
Journal Article
Yu, D., Qu, B., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., …Simmons, D. (2023). Association Between Onset of Type 2 Diabetes and Risk of Atrial Fibrillation in New Zealanders With Impaired Glucose Tolerance Over 25 Years. Journal of the American Heart Association, 12(18), Article e030159. https://doi.org/10.1161/JAHA.123.030159

Background
The association between the onset of type 2 diabetes (T2D) and atrial fibrillation (AF) risk in individuals with impaired glucose tolerance (IGT) remains unclear. This study aimed to investigate the relationship between the incident onset... Read More about Association Between Onset of Type 2 Diabetes and Risk of Atrial Fibrillation in New Zealanders With Impaired Glucose Tolerance Over 25 Years.

Real‐world evidence that among atrial fibrillation patients warfarin is associated with reduced nonelective admissions compared with those on DOACs (2023)
Journal Article
Yu, D., Brown, J., David Strain, W., & Simmons, D. (2023). Real‐world evidence that among atrial fibrillation patients warfarin is associated with reduced nonelective admissions compared with those on DOACs. Clinical Cardiology, https://doi.org/10.1002/clc.24146

Background: Randomized trials show inconsistent estimates on risks of direct‐acting oral anticoagulants (DOACs) versus warfarin in bleeding and mortality for atrial fibrillation (AF) patients. Trials are confounded by additional DOAC adherence suppor... Read More about Real‐world evidence that among atrial fibrillation patients warfarin is associated with reduced nonelective admissions compared with those on DOACs.

Use of non-surgical treatments on the journey to knee replacement in patients with knee osteoarthritis: a 10-year population-based case–control study (2023)
Journal Article
Dell'Isola, A., Hellberg, C., Turkiewicz, A., Appleyard, T., Yu, D., Thomas, G., …Englund, M. (2023). Use of non-surgical treatments on the journey to knee replacement in patients with knee osteoarthritis: a 10-year population-based case–control study. RMD Open, 9(3), Article e003422. https://doi.org/10.1136/rmdopen-2023-003422

Aim: To investigate temporal trends in primary care visits, physiotherapy visits, dispensed non-steroidal anti-inflammatory drugs (NSAIDs) and opioids in knee osteoarthritis (OA) patients who have and have not undergone knee replacement.

Methods:... Read More about Use of non-surgical treatments on the journey to knee replacement in patients with knee osteoarthritis: a 10-year population-based case–control study.

Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017 (2023)
Journal Article
Yu, D., Huang, X., Mamas, M., & Wilkie, R. (2023). Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017. RMD Open, 9(3), Article e003298. https://doi.org/10.1136/rmdopen-2023-003298

Objectives: To compare the annual and period prevalence of modifiable cardiovascular risk factors (MCVRFs) between populations with and without osteoarthritis (OA) in the UK over 25 years.

Methods: 215 190 patients aged 35 years and over from the... Read More about Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017.

Time to Benefit of Sodium-Glucose Cotransporter-2 Inhibitors Among Patients With Heart Failure (2023)
Journal Article
Chen, K., Nie, Z., Shi, R., Yu, D., Wang, Q., Shao, F., …Li, C. (2023). Time to Benefit of Sodium-Glucose Cotransporter-2 Inhibitors Among Patients With Heart Failure. Jama Network Open, 6(8), Article e2330754. https://doi.org/10.1001/jamanetworkopen.2023.30754

IMPORTANCE Emerging evidence has consistently demonstrated that sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of heart failure (HF) hospitalization and cardiovascular (CV) death among patients with HF. However, it remains unclear... Read More about Time to Benefit of Sodium-Glucose Cotransporter-2 Inhibitors Among Patients With Heart Failure.

Effect of onset of type 2 diabetes on risks of cardiovascular disease and heart failure among new Zealanders with impaired glucose tolerance over 25 years: tapered-matched landmark analysis (2023)
Journal Article
Yu, D., Qu, B., Levi Osuagwu, U., Pickering, K., Baker, J., Cutfield MBChB, R., …Simmons, D. (2023). Effect of onset of type 2 diabetes on risks of cardiovascular disease and heart failure among new Zealanders with impaired glucose tolerance over 25 years: tapered-matched landmark analysis. Cardiovascular Diabetology, 22(1), Article 163. https://doi.org/10.1186/s12933-023-01871-y

Background
This study aimed to examine the association between the incident onset of T2DM and 5- and 10-year risks of CVD and HF in people with IGT identified in primary care in South and West Auckland, New Zealand (NZ) between 1994 and 2019.

Met... Read More about Effect of onset of type 2 diabetes on risks of cardiovascular disease and heart failure among new Zealanders with impaired glucose tolerance over 25 years: tapered-matched landmark analysis.

Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain (2023)
Journal Article
Lynch, M., Peat, G., Jordan, K., Yu, D., & Wilkie, R. (2023). Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain. European Journal of Pain, https://doi.org/10.1002/ejp.2148

Background
Chronic pain affects up to half of UK adults, impacting quality of life and demand on local health services. Whilst local health planning is currently based on subnational prevalence estimates, associations between pain and sociodemograph... Read More about Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain.

Adverse Clinical Outcomes Attributable to Socioeconomic and Ethnic Disparities Among People with Type 2 Diabetes in New Zealand Between 1994–2018: A Multiple Linked Cohort Study (2023)
Journal Article
Yu, D., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., Wang, Z., …Simmons, D. (2023). Adverse Clinical Outcomes Attributable to Socioeconomic and Ethnic Disparities Among People with Type 2 Diabetes in New Zealand Between 1994–2018: A Multiple Linked Cohort Study. Clinical Epidemiology, 15, 511 - 523. https://doi.org/10.2147/CLEP.S402307

Purpose: The study aimed to examine the separate population-level contributions of the ethnic and socioeconomic disparities among people with type 2 diabetes mellitus (T2DM) and residence in New Zealand (NZ).
Patients and Methods: A prospective coho... Read More about Adverse Clinical Outcomes Attributable to Socioeconomic and Ethnic Disparities Among People with Type 2 Diabetes in New Zealand Between 1994–2018: A Multiple Linked Cohort Study.