A Randomized Trial of Autologous Chondrocyte Implantation Versus Alternative Forms of Surgical Cartilage Management in Patients With a Failed Primary Treatment for Chondral or Osteochondral Defects in the Knee

Snow, Martyn; Middleton, Lee; Mehta, Samir; Roberts, Andrew; Gray, Richard; Richardson, James; Kuiper, Jan Herman; Smith, Anthony; White, Steve; Roberts, Simon; Griffiths, David; Mohammed, Aslam; Moholkar, Kirti; Ashraf, Tanweer; Green, Marcus; Hutchinson, James; Bhullar, Tony; Chitnis, Sanjeev; Shaw, Andrew; van Niekerk, Louw; Hui, Anthony; Drogset, Jon Olav; Knutsen, Gunnar; McNicholas, Mike; Bowditch, Mark; Johnson, David; Turner, Philip; Chugh, Sanjiv; Hunt, Neil; Ali, Salman; Palmer, Simon; Perry, Andrew; Davidson, Alastair; Hill, Peter; Deo, Sunny; Satish, Venkat; Radford, Michael; Langstaff, Ron; Houlihan-Burne, David; Spicer, Dominic; Phaltankar, Padman; Hegab, Ahmed; Marsh, David; Cannon, Steve; Briggs, Tim; Pollock, Rob; Carrington, Richard; Skinner, John; Bentley, George; Price, Andrew; Schranz, Peter; Mandalia, Vipul; O’Brien, Shaun

doi:10.1177/03635465221141907

All Outputs (7)

EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW (2023)
Presentation / Conference Contribution
Rix, L., Tushingham, S., Wright, K., & Snow, M. EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW. Presented at The British Orthopaedic Research Society (BORS) 2023 Meeting (25–26 September 2023), Cambridge, England

AbstractObjectiveA common orthopaedic pain found in a wide spectrum of individuals, from young and active to the elderly is anterior knee pain (AKP). It is a multifactorial disorder which is thought to occur through muscular imbalance, overuse, traum... Read More about EVALUATING THE UTILITY OF SPECT/CT FOR THE IDENTIFICATION OF CARTILAGE LESIONS: A SYSTEMATIC REVIEW.

Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration (2023)
Journal Article
Atwal, A., Dale, T. P., Snow, M., Forsyth, N. R., & Davoodi, P. (2023). Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration. Advances in colloid and interface science, 321, Article 103030. https://doi.org/10.1016/j.cis.2023.103030

The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed significant challenges for healthcare practitioners, researchers, and individuals suffering from these conditions. Due to the absence of an approved treatmen... Read More about Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration.

A novel injectable hydrogel-based drug delivery system for the repair of cartilage defects (2023)
Presentation / Conference
Atwal, A., Davoodi, P., Forsyth, N. R., & Snow, M. (2023, March). A novel injectable hydrogel-based drug delivery system for the repair of cartilage defects. Presented at TERMIS 2023 – European Chapter, Manchester Central Conference Centre Manchester, UK

Fabrication of an injectable hydrogel with controllable in situ pore formation for the repair of chondral lesions (2023)
Presentation / Conference
Atwal, A., Davoodi, P., Forsyth, N. R., & Snow, M. (2023, March). Fabrication of an injectable hydrogel with controllable in situ pore formation for the repair of chondral lesions. Poster presented at TERMIS 2023 – European Chapter, Manchester Central Conference Centre Manchester, UK

Assessing Allogeneic Chondroprogenitor Manufacture Under Good Manufacturing Practice (GMP) Serum Free And Xeno-Free Conditions. (2023)
Presentation / Conference Contribution
McCarthy, Hulme, Perry, J., & Snow, D. Assessing Allogeneic Chondroprogenitor Manufacture Under Good Manufacturing Practice (GMP) Serum Free And Xeno-Free Conditions

Assessing Allogenic Chondroprogenitor Manufacture Under Good Manufacturing Practice (GMP) Serum Free And Xeno-Free Conditions (2023)
Presentation / Conference Contribution
Perry, J., Hulme, C., Rix, L., Mccarthy, H., Lan, T., Roberts, S., Snow, M., & Wright, K. (2023, March). Assessing Allogenic Chondroprogenitor Manufacture Under Good Manufacturing Practice (GMP) Serum Free And Xeno-Free Conditions. Poster presented at 2023 OARSI World Congress on Osteoarthritis, Denver, Colorado

A Randomized Trial of Autologous Chondrocyte Implantation Versus Alternative Forms of Surgical Cartilage Management in Patients With a Failed Primary Treatment for Chondral or Osteochondral Defects in the Knee (2023)
Journal Article
Snow, M., Middleton, L., Mehta, S., Roberts, A., Gray, R., Richardson, J., Kuiper, J. H., Smith, A., White, S., Roberts, S., Griffiths, D., Mohammed, A., Moholkar, K., Ashraf, T., Green, M., Hutchinson, J., Bhullar, T., Chitnis, S., Shaw, A., van Niekerk, L., …O’Brien, S. (2023). A Randomized Trial of Autologous Chondrocyte Implantation Versus Alternative Forms of Surgical Cartilage Management in Patients With a Failed Primary Treatment for Chondral or Osteochondral Defects in the Knee. American Journal of Sports Medicine, 51(2), 367-378. https://doi.org/10.1177/03635465221141907

BACKGROUND: There are limited randomized controlled trials with long-term outcomes comparing autologous chondrocyte implantation (ACI) versus alternative forms of surgical cartilage management within the knee. PURPOSE: To determine at 5 years after s... Read More about A Randomized Trial of Autologous Chondrocyte Implantation Versus Alternative Forms of Surgical Cartilage Management in Patients With a Failed Primary Treatment for Chondral or Osteochondral Defects in the Knee.