All Outputs (2)

Anti-inflammatory effects of epoxyeicosatrienoic acids (EETs) and their corresponding diols against pro-inflammatory cytokine-toxicity in BRIN-BD11 cells. (2018)
Presentation / Conference
Watson. (2018, March). Anti-inflammatory effects of epoxyeicosatrienoic acids (EETs) and their corresponding diols against pro-inflammatory cytokine-toxicity in BRIN-BD11 cells. Poster presented at Diabetes UK Professional Conference 2018, London ExCeL, London

Introduction: CYP450-derived EETs display anti-inflammatory activity in cardiac models of inflammation, in part through activation of Peroxisome proliferator-activated receptor gamma (PPARγ) and inhibition of Nuclear Factor kappa B (NF-kB) activation... Read More about Anti-inflammatory effects of epoxyeicosatrienoic acids (EETs) and their corresponding diols against pro-inflammatory cytokine-toxicity in BRIN-BD11 cells..

Apoptosis Suppression by Candidate Oncogene PLAC8 is Reversed in Other Cell Types (2013)
Journal Article
Mourtada-Maarabouni, M., Watson, D., Munir, M., Farzaneh, F., & T. Williams, G. (2013). Apoptosis Suppression by Candidate Oncogene PLAC8 is Reversed in Other Cell Types. Current Cancer Drug Targets, 13(1), 80-91. https://doi.org/10.2174/156800913804486584

Targets for cancer therapy are conventionally selected by identification of molecules acting downstream of established tumour suppressors and oncoproteins, such as p53, c-Myc and Ras. However, the forward genetics approach provides an alternative, co... Read More about Apoptosis Suppression by Candidate Oncogene PLAC8 is Reversed in Other Cell Types.