All Outputs (3)

Epoxyeicosatrienoic acids protect pancreatic beta cells against pro-inflammatory cytokine toxicity (2019)
Journal Article
Watson. (2019). Epoxyeicosatrienoic acids protect pancreatic beta cells against pro-inflammatory cytokine toxicity. Biochemical and Biophysical Research Communications, 231-236. https://doi.org/10.1016/j.bbrc.2019.09.124

Pro-inflammatory cytokines contribute to pancreatic beta cell death in the pathogenesis of type 1 diabetes mellitus (DM). Cytochrome P450-derived epoxyeicosatrienoic acids (EETs), produced by selective epoxidation of arachidonic acid, display anti-in... Read More about Epoxyeicosatrienoic acids protect pancreatic beta cells against pro-inflammatory cytokine toxicity.

Apoptosis Suppression by Candidate Oncogene PLAC8 is Reversed in Other Cell Types (2013)
Journal Article
Mourtada-Maarabouni, M., Watson, D., Munir, M., Farzaneh, F., & T. Williams, G. (2013). Apoptosis Suppression by Candidate Oncogene PLAC8 is Reversed in Other Cell Types. Current Cancer Drug Targets, 13(1), 80-91. https://doi.org/10.2174/156800913804486584

Targets for cancer therapy are conventionally selected by identification of molecules acting downstream of established tumour suppressors and oncoproteins, such as p53, c-Myc and Ras. However, the forward genetics approach provides an alternative, co... Read More about Apoptosis Suppression by Candidate Oncogene PLAC8 is Reversed in Other Cell Types.

Oxidative and nitrosative stress in β-cell apoptosis: their contribution to β-cell lossin type 1 diabetes mellitus (2009)
Journal Article
Watson, D., & Loweth, A. C. (2009). Oxidative and nitrosative stress in β-cell apoptosis: their contribution to β-cell lossin type 1 diabetes mellitus. British Journal of Biomedical Science, 66(4), 208-215. https://doi.org/10.1080/09674845.2009.11730278