All Outputs (3)

EP-273 Magnetic nanoparticle administration to a model of penetrating neurotrauma in vitro (2022)
Journal Article
Chari, D., Basit, R. H., Wiseman, J., & Chari, D. M. (2022). EP-273 Magnetic nanoparticle administration to a model of penetrating neurotrauma in vitro. British Journal of Surgery, 109(Supplement_5), https://doi.org/10.1093/bjs/znac245.072

Introduction/Aims Functional recovery in penetrating traumatic brain injury (pTBI) is hampered due to the lack of clinically approved regenerative therapies. Although a surgical emergency, pTBI management is largely supportive, with no targeted neuro... Read More about EP-273 Magnetic nanoparticle administration to a model of penetrating neurotrauma in vitro.

SP5.1.1 Novel in vitro model of neurotrauma to study neurotherapeutics (2022)
Journal Article
Chari, Basit, R. H., Wiseman, J., & Chari, D. M. (2022). SP5.1.1 Novel in vitro model of neurotrauma to study neurotherapeutics. British Journal of Surgery, 109(Supplement_5), https://doi.org/10.1093/bjs/znac247.047

Introduction/Aims Penetrating traumatic brain injury (pTBI) is a surgical emergency, with poor clinical outcomes. Management is supportive including surgical wound debridement, anti-epileptic administration and infection prophylaxis; no clinical neur... Read More about SP5.1.1 Novel in vitro model of neurotrauma to study neurotherapeutics.

Transplantation of encapsulated autologous olfactory ensheathing cell populations expressing chondroitinase for spinal cord injury: A safety and feasibility study in companion dogs (2022)
Journal Article
Prager, J., Fenn, J., Plested, M., Escauriaza, L., Merwe, T. V. D., King, B., …Granger, N. (2022). Transplantation of encapsulated autologous olfactory ensheathing cell populations expressing chondroitinase for spinal cord injury: A safety and feasibility study in companion dogs. Journal of Tissue Engineering and Regenerative Medicine, 16(9), 788-798. https://doi.org/10.1002/term.3328

Spinal cord injury (SCI) can cause irreversible paralysis, with no regenerative treatment clinically available. Dogs with natural SCI present an established model and can facilitate translation of experimental findings in rodents to people. We cond... Read More about Transplantation of encapsulated autologous olfactory ensheathing cell populations expressing chondroitinase for spinal cord injury: A safety and feasibility study in companion dogs.