Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices

Adams, CF; Delaney, AM; Carwardine, DR; Tickle, J; Granger, N; Chari, DM

doi:10.1002/mabi.201800389

All Outputs (4)

INSPIRing medical undergraduates to do research: the career impacts of a summer studentship programme (2019)
Journal Article
Hider, S., Seale, B., Vivekanatham, A., Woods, W., & Chari, D. (2019). INSPIRing medical undergraduates to do research: the career impacts of a summer studentship programme. British Student Doctor, 2 - 2. https://doi.org/10.18573/bsdj.110

Guest Editorial.

Less is more: Investigating the influence of cellular nanoparticle load on transfection outcomes in neural cells (2019)
Journal Article
Chari, D. M., & Tickle, J. A. (2019). Less is more: Investigating the influence of cellular nanoparticle load on transfection outcomes in neural cells. Journal of Tissue Engineering and Regenerative Medicine, https://doi.org/10.1002/term.2909

Genetic engineering of cell transplant populations offers potential for delivery of neurotherapeutic factors to modify the regenerative microenvironment of the injured spinal cord. The use of magnetic nanoparticle (MNP) based vectors has reduced the... Read More about Less is more: Investigating the influence of cellular nanoparticle load on transfection outcomes in neural cells.

Neurosurgical grade biomaterial, DuraGenTM, offers a promising matrix for protected delivery of neural stem cells in clinical cell therapies (2019)
Journal Article
Finch, L., Adams, C., Sen, J., Tickle, J., Tzerakis, N., & Chari, D. M. (2019). Neurosurgical grade biomaterial, DuraGenTM, offers a promising matrix for protected delivery of neural stem cells in clinical cell therapies. Future Healthcare Journal, 6(Suppl 1), 76-76. https://doi.org/10.7861/futurehosp.6-1-s76

Aims Transplantation of neural stem cells (NSCs) into sites of neurological injury is being investigated in clinical trials around the world. These important self-renewing and multipotent precursors can generate the major central nervous system cell... Read More about Neurosurgical grade biomaterial, DuraGenTM, offers a promising matrix for protected delivery of neural stem cells in clinical cell therapies.

Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices (2019)
Journal Article
Adams, C., Delaney, A., Carwardine, D., Tickle, J., Granger, N., & Chari, D. (2019). Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices. Macromolecular Bioscience, 19, e1800389. https://doi.org/10.1002/mabi.201800389

A recent clinical trial proves that autologous olfactory mucosal cell (OMC) transplantation improves locomotion in dogs with naturally occurring spinal injuries comparable to human lesions. However, not all dogs respond to the treatment, likely due t... Read More about Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices.