All Outputs (273)

Clinical and cost-effectiveness of a personalised guided consultation versus usual physiotherapy care in people presenting with shoulder pain: a protocol for the PANDA-S cluster randomised controlled trial and process evaluation (2025)
Journal Article
A Harrisson, S., Myers, H., Wynne Jones, G., Bajpai, R., Bratt, C., Burton, C., Harrison, R., Jowett, S., A Lawton, S., Saunders, B., J Beard, D., Bucknall, M., Chester, R., Heneghan, C., Huckfield, L., Lewis, M., D Mallen, C., Pincus, T., L Rees, J., Roddy, E., & A Van der Windt, D. (2025). Clinical and cost-effectiveness of a personalised guided consultation versus usual physiotherapy care in people presenting with shoulder pain: a protocol for the PANDA-S cluster randomised controlled trial and process evaluation. BMJ Open, 15(5), https://doi.org/10.1136/bmjopen-2025-100501

Introduction: Musculoskeletal shoulder pain is a common reason for people to be treated in physiotherapy services, but diagnosis can be difficult and often does not guide treatment or predict outcome. People with shoulder pain cite a need for clear i... Read More about Clinical and cost-effectiveness of a personalised guided consultation versus usual physiotherapy care in people presenting with shoulder pain: a protocol for the PANDA-S cluster randomised controlled trial and process evaluation.

Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial (2025)
Other
Thomas, M. J., Hughes, G., Cooke, K., Butler-Walley, S., Marshall, E., Bowyer, L., Wathall, S., Smith, J., Lawton, S. A., Brammar, J., Burnett, T., Drake, C., Foster, N. E., Hendry, G. J., Holden, M. A., Jaki, T., Joseph, R., Keenan, A.-M., Kigozi, J., Lewis, M., …Roddy, E. (2025). Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial

Background
Plantar heel pain (PHP) is the most common soft tissue foot condition and impairs mobility, physical function, ability to work, and quality of life. Systematic reviews highlight a need for high-quality randomised controlled trials (RCTs)... Read More about Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial.

P087 Cardioprotective effects of colchicine in people with gout: a systematic review (2025)
Presentation / Conference Contribution
Prior, J. A., Umar, Z., Ibrahim, N., Bajpai, R., Partington, R., Mamas, M., & Roddy, E. (2025, April). P087 Cardioprotective effects of colchicine in people with gout: a systematic review. Poster presented at British Society for Rheumatology Annual Conference 2025, Manchester Central Convention Complex, Manchester, England UK

Background/Aims Colchicine is widely used in clinical practice to prevent and treat gout flares. Randomised controlled trials (RCT) have demonstrated cardiovascular benefits of colchicine in people with chronic coronary artery disease (CAD) or a rece... Read More about P087 Cardioprotective effects of colchicine in people with gout: a systematic review.

OA01 Long-term cardiovascular safety of febuxostat compared with allopurinol or no urate-lowering treatment in people with gout: a cohort study in UK primary care using the Clinical Practice Research Datalink (2025)
Presentation / Conference Contribution
Partington, R., Muller, S., Mallen, C. D., Mamas, M. A., Forrester, H., & Roddy, E. (2025, April). OA01 Long-term cardiovascular safety of febuxostat compared with allopurinol or no urate-lowering treatment in people with gout: a cohort study in UK primary care using the Clinical Practice Research Datalink. Presented at British Society for Rheumatology Annual Conference, Manchester Central Convention Complex, Manchester, England

Background/Aims Febuxostat is recommended as first line urate-lowering therapy (ULT) for gout in the UK. However, concerns were raised regarding its cardiovascular (CV) safety. Current guidance advises caution when using it in people with CV disease,... Read More about OA01 Long-term cardiovascular safety of febuxostat compared with allopurinol or no urate-lowering treatment in people with gout: a cohort study in UK primary care using the Clinical Practice Research Datalink.

Physical Impairments in People With Gout: A Scoping Review (2025)
Journal Article
Kumar, P., Buckley, J., Roddy, E., & Thomas, M. J. (2025). Physical Impairments in People With Gout: A Scoping Review. Musculoskeletal Care, 23(2), 1-28. https://doi.org/10.1002/msc.70103

Introduction: Gout is the most common form of inflammatory arthritis. It is predominantly managed with pharmacological interventions, and physical impairments in people with gout have seldom been studied. We aimed to identify gout‐related physical im... Read More about Physical Impairments in People With Gout: A Scoping Review.

Footwear Toe‐Box Shape and Medial Forefoot Pressures in Women With Hallux Valgus (2025)
Journal Article
Bajraszewski, K. J., Lim, P. Q. X., Buldt, A. K., Hurn, S. E., Mickle, K. J., Roddy, E., Wluka, A. E., Erbas, B., Munteanu, S. E., & Menz, H. B. (2025). Footwear Toe‐Box Shape and Medial Forefoot Pressures in Women With Hallux Valgus. Journal of Foot and Ankle Research, 18(2), Article e70041. https://doi.org/10.1002/jfa2.70041

Background: Narrow fitting footwear is a modifiable risk factor for the development of hallux valgus (HV). Despite this, the pressure that footwear exerts at the medial forefoot has not been fully evaluated in people with HV. Therefore, the objective... Read More about Footwear Toe‐Box Shape and Medial Forefoot Pressures in Women With Hallux Valgus.

Executive Summary: The British Society for Rheumatology guideline for the management of foot health in inflammatory arthritis (2025)
Journal Article
Chapman, L. S., Backhouse, M., Corp, N., van der Windt, D., Bearne, L., Cherry, L., Cleary, G., Davey, J., Ferguson, R., Helliwell, P., Lomax, A., McKeeman, H., Rawlings, A. A., Rees, R., Rooney, R., Ryan, S., Sanders, L., Siddle, H. J., Varley, S., Warburton, L., …Roddy, E. (2025). Executive Summary: The British Society for Rheumatology guideline for the management of foot health in inflammatory arthritis. Rheumatology, 1-8. https://doi.org/10.1093/rheumatology/keaf072

The British Society for Rheumatology guideline for the management of foot health in inflammatory arthritis (2025)
Journal Article
Chapman, L. S., Backhouse, M., Corp, N., van der Windt, D., Bearne, L., Cherry, L., Cleary, G., Davey, J., Ferguson, R., Helliwell, P., Lomax, A., McKeeman, H., Rawlings, A. A., Rees, R., Rooney, R., Ryan, S., Sanders, L., Siddle, H. J., Varley, S., Warburton, L., …Roddy, E. (2025). The British Society for Rheumatology guideline for the management of foot health in inflammatory arthritis. Rheumatology, 1-14. https://doi.org/10.1093/rheumatology/keaf071

Should all people starting urate-lowering therapy for gout receive anti-inflammatory prophylaxis? (2024)
Journal Article
Roddy, E., Prior, J. A., & Mallen, C. D. (2024). Should all people starting urate-lowering therapy for gout receive anti-inflammatory prophylaxis?. Exploration of Musculoskeletal Diseases, 2, 521-528. https://doi.org/10.37349/emd.2024.00076

Co-prescription of anti-inflammatory prophylaxis with colchicine, non-steroidal anti-inflammatory drugs (NSAIDs), or corticosteroids when initiating urate-lowering therapy (ULT) for gout is recommended in clinical guidelines to prevent ULT-induced fl... Read More about Should all people starting urate-lowering therapy for gout receive anti-inflammatory prophylaxis?.

Trends in Management and Consultations for Gout: A Study of 18 Million Adults Using the OpenSAFELY Platform (2024)
Presentation / Conference Contribution
Russell, M., Massey, J., Roddy, E., MacKenna, B., Bacon, S., Goldacre, B., Andrews, C., Hickman, G., Mehrkar, A., Mahto, A., Rutherford, A., Patel, S., Adas, M., Alveyn, E., Nagra, . D., Bechman, K., Ledingham, J., Hudson, J., Norton, S., Cope, A., & Galloway, J. (2024, November). Trends in Management and Consultations for Gout: A Study of 18 Million Adults Using the OpenSAFELY Platform. Poster presented at Abstract Supplement ACR Convergence 2024, Washington DC

Background/Purpose: Data from before the COVID-19 pandemic had shown persistently poor care for people with gout in many countries worldwide. Whether this was further exacerbated by the pandemic is not fully understood. Our objective was to investiga... Read More about Trends in Management and Consultations for Gout: A Study of 18 Million Adults Using the OpenSAFELY Platform.

Publisher Correction: A genome-wide association analysis reveals new pathogenic pathways in gout. (2024)
Journal Article
Major, T. J., Takei, R., Matsuo, H., Leask, M. P., Sumpter, N. A., Topless, R. K., Shirai, Y., Wang, W., Cadzow, M. J., Phipps-Green, A. J., Li, Z., Ji, A., Merriman, M. E., Morice, E., Kelley, E. E., Wei, W.-H., McCormick, S. P. A., Bixley, M. J., Reynolds, R. J., Saag, K. G., …Merriman, T. R. (2024). Publisher Correction: A genome-wide association analysis reveals new pathogenic pathways in gout. Nature Genetics, 56(11), Article 2577. https://doi.org/10.1038/s41588-024-02017-w

In the version of the article originally published, there were errors in the consortium lists at the end of the paper. Maureen Rischmueller, Hyon K. Choi, Masahiro Nakatochi, Jeff N. Miner, Daniel H. Solomon, Kathleen M. Giacomini and Deanna J. Brack... Read More about Publisher Correction: A genome-wide association analysis reveals new pathogenic pathways in gout..

A genome-wide association analysis reveals new pathogenic pathways in gout. (2024)
Journal Article
Major, T. J., Takei, R., Matsuo, H., Leask, M. P., Sumpter, N. A., Topless, R. K., Shirai, Y., Wang, W., Cadzow, M. J., Phipps-Green, A. J., Li, Z., Ji, A., Merriman, M. E., Morice, E., Kelley, E. E., Wei, W.-H., McCormick, S. P. A., Bixley, M. J., Reynolds, R. J., Saag, K. G., …Merriman, T. R. (in press). A genome-wide association analysis reveals new pathogenic pathways in gout. Nature Genetics, https://doi.org/10.1038/s41588-024-01921-5

Gout is a chronic disease that is caused by an innate immune response to deposited monosodium urate crystals in the setting of hyperuricemia. Here, we provide insights into the molecular mechanism of the poorly understood inflammatory component of go... Read More about A genome-wide association analysis reveals new pathogenic pathways in gout..

Pain Reduction With Oral Methotrexate in Knee Osteoarthritis (2024)
Journal Article
Kingsbury, S. R., Tharmanathan, P., Keding, A., Watt, F. E., Scott, D. L., Roddy, E., Birrell, F., Arden, N. K., Bowes, M., Arundel, C., Watson, M., Ronaldson, S. J., Hewitt, C., Doherty, M., Moots, R. J., O’Neill, T. W., Green, M., Patel, G., Garrood, T., Edwards, C. J., …Conaghan, P. G. (in press). Pain Reduction With Oral Methotrexate in Knee Osteoarthritis. Annals of Internal Medicine, 177(9), https://doi.org/10.7326/m24-0303

AB0105 ‘..THERE’S TOO MUCH TO PUT IN A LEAFLET’: A QUALITATIVE EXPLORATION OF STAKEHOLDER VIEWS OF LIFESTYLE INTERVENTIONS FOR GOUT (2024)
Presentation / Conference Contribution
Watson, L., Cornwall, N., Jinks, C., Bradbury, K., Goff, L., Little, P., Mallen, C., & Roddy, E. (2024, June). AB0105 ‘..THERE’S TOO MUCH TO PUT IN A LEAFLET’: A QUALITATIVE EXPLORATION OF STAKEHOLDER VIEWS OF LIFESTYLE INTERVENTIONS FOR GOUT. Paper presented at EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria, Vienna

Background: Lifestyle has been associated with gout for centuries and dietary triggers of flares remain of great interest to people with gout. However, there is a lack of robust clinical trial evidence about the eff... Read More about AB0105 ‘..THERE’S TOO MUCH TO PUT IN A LEAFLET’: A QUALITATIVE EXPLORATION OF STAKEHOLDER VIEWS OF LIFESTYLE INTERVENTIONS FOR GOUT.

P086 Trends in the Incidence and Management of Gout in England: A Nationwide Study using the OpenSAFELY Platform (2024)
Presentation / Conference Contribution
Russell, M. D., Massey, J., Roddy, E., MacKenna, B., Bacon, S., Goldacre, B., Andrews, C. D., Hickman, G., Mehrkar, A., Mahto, A., Rutherford, A. I., Patel, S., Adas, M. A., Alveyn, E., Nagra, D., Bechman, K., Ledingham, J. M., Hudson, J., Norton, S., Cope, A., & Galloway, J. (2024, April). P086 Trends in the Incidence and Management of Gout in England: A Nationwide Study using the OpenSAFELY Platform. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Gout is the most common inflammatory arthritis worldwide, yet one of the worst managed. Few population-level studies have evaluated how the COVID-19 pandemic impacted on incidence, prevalence, management and hospitalisations for peopl... Read More about P086 Trends in the Incidence and Management of Gout in England: A Nationwide Study using the OpenSAFELY Platform.

P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review (2024)
Presentation / Conference
Dahanayake, C., Bajpai, R., Jordan, K. M., Lambie, M., & Roddy, E. (2024, April). P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims
Uric acid nephrolithiasis is a recognised side-effect of uricosuric therapies and a contraindication to their use. The objective of this systematic review was to assess the incidence and risk of nephrolithiasis in people with gout re... Read More about P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review.

P085 Implementing treat-to-target urate-lowering therapy during hospitalisations for gout flares: a prospective cohort study (2024)
Presentation / Conference Contribution
Russell, M. D., Ameyaw-Kyeremeh, L., Dell'Accio, F., Lapham, H., Head, N., Stovin, C., Patel, V., Clarke, B., Nagra, D., Alveyn, E., Adas, M. A., Bechman, K., de la Puente, M. A., Ellis, B., Byrne, C., Patel, R., Rutherford, A. I., Cantle, F., Norton, S., Roddy, E., …Galloway, J. B. (2024, April). P085 Implementing treat-to-target urate-lowering therapy during hospitalisations for gout flares: a prospective cohort study. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Hospitalisations for gout flares have doubled in England during the last 15 years. Despite this, no studies have evaluated strategies designed to increase the uptake of urate-lowering therapy (ULT) in people hospitalised for gout flar... Read More about P085 Implementing treat-to-target urate-lowering therapy during hospitalisations for gout flares: a prospective cohort study.

Effectiveness of footwear and foot orthoses in reducing medial metatarsophangeal joint pressure in women with hallux valgus (2024)
Journal Article
Menz, H. B., Lim, P. Q., Hurn, S. E., Mickle, K. J., Buldt, A. K., Cotchett, M. P., Roddy, E., Wluka, A. E., Erbas, B., & Munteanu, S. E. (in press). Effectiveness of footwear and foot orthoses in reducing medial metatarsophangeal joint pressure in women with hallux valgus. Gait & Posture, 111, 156-161. https://doi.org/10.1016/j.gaitpost.2024.04.021

Background
Hallux valgus is a common condition where the subluxation of the first metatarsophalangeal joint and lateral deviation of the hallux at the interphalangeal joint creates difficulty with footwear fit. Fo... Read More about Effectiveness of footwear and foot orthoses in reducing medial metatarsophangeal joint pressure in women with hallux valgus.

Effectiveness of footwear and foot orthoses in reducing medial metatarsophalangeal joint pressure in women with hallux valgus (2024)
Journal Article
Roddy, E., Menz, H., Lim, P., Hurn, S., Mickle, K., Buldt, A., Cotchett, M., Wluka, A., Erbas, B., & Munteanu, S. (2024). Effectiveness of footwear and foot orthoses in reducing medial metatarsophalangeal joint pressure in women with hallux valgus. Gait and Posture, 111, 156-161. https://doi.org/10.1016/j.gaitpost.2024.04.021

Background
Hallux valgus is a common condition where the subluxation of the first metatarsophalangeal joint and lateral deviation of the hallux at the interphalangeal joint creates difficulty with footwear fit. Footwear and foot orthoses are commonl... Read More about Effectiveness of footwear and foot orthoses in reducing medial metatarsophalangeal joint pressure in women with hallux valgus.

269 CLINICAL GUIDELINE RESEARCH RECOMMENDATIONS FOR THE NON-SURGICAL MANAGEMENT OF OSTEOARTHRITIS: A THEMATIC SYNTHESIS. (2024)
Presentation / Conference Contribution
Woodcock, C., English, E., Jinks, C., Healey, E. L., Parry, E., Paskins, Z., Roddy, E., Simkins, J., Thomas, M., Bennell, K., Hinman, R. S., & Holden, M. (2024, April). 269 CLINICAL GUIDELINE RESEARCH RECOMMENDATIONS FOR THE NON-SURGICAL MANAGEMENT OF OSTEOARTHRITIS: A THEMATIC SYNTHESIS. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria