Skip to main content

Research Repository

Advanced Search

All Outputs (258)

O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink (2015)
Journal Article
Clarson, L. E., Hider, S. L., Belcher, J., Roddy, E., Heneghan, C., & Mallen, C. D. (2015). O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink. Rheumatology, 54(S1), https://doi.org/10.1093/rheumatology/kev084.001

Background: Current evidence suggests that gout is an independent risk factor for excess cardiovascular morbidity and mortality; yet, suboptimal care for patients with gout in primary care persists. We aimed to identify risk factors specific to these... Read More about O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink.

O35. Population Prevalence and Associations of Plantar Heel Pain in Adults Aged 50 Years and Over: Cross-Sectional Findings from the Clinical Assessment Study of the Foot (2015)
Journal Article
Roddy, E., Case, R., Thomas, M. J., Menz, H. B., Rathod, T., & Marshall, M. O35. Population Prevalence and Associations of Plantar Heel Pain in Adults Aged 50 Years and Over: Cross-Sectional Findings from the Clinical Assessment Study of the Foot. Rheumatology, 54(S1), i39–i40. https://doi.org/10.1093/rheumatology/kev084.005

Background: Plantar heel pain is a very common presentation to primary care and yet among the most difficult to manage. There is a lack of epidemiological evidence on the rates of consultation for the condition and of the health status of affected in... Read More about O35. Population Prevalence and Associations of Plantar Heel Pain in Adults Aged 50 Years and Over: Cross-Sectional Findings from the Clinical Assessment Study of the Foot.

Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies (2015)
Journal Article
Mallen, Roddy, & Belcher. (2015). Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies. Arthritis Research and Therapy, 17, Article 90. https://doi.org/10.1186/s13075-015-0610-9

ntroduction To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis. Methods Systematic review and meta-... Read More about Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies.

Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trial (2015)
Journal Article
Roddy, E. (2015). Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trial. Trials, 77 - ?. https://doi.org/10.1186/s13063-015-0602-8

BACKGROUND: Osteoarthritis (OA) is the fastest growing cause of disability worldwide. Current treatments for OA are severely limited and a large proportion of people with OA live in constant, debilitating pain. There is therefore an urgent need for n... Read More about Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trial.

Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis (2015)
Journal Article
Roddy, Mallen, Belcher, Clarson, & Hider. (2015). Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis. European Journal of Preventive Cardiology, 22(3), 335 -343. https://doi.org/10.1177/2047487313514895

BACKGROUND: Hyperuricaemia, the biochemical precursor to gout, has been shown to be an independent risk factor for mortality from cardiovascular disease (CVD), although studies examining the clinical phenomenon of gout and risk of CVD mortality repor... Read More about Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis.

Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink (2015)
Journal Article
Roddy, Mallen, Belcher, & Hider. (2015). Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink. Annals of the Rheumatic Diseases, 642 - 647. https://doi.org/10.1136/annrheumdis-2014-206432

OBJECTIVES: To determine whether gout increases risk of incident coronary heart disease (CHD), cerebrovascular (CVD) and peripheral vascular disease (PVD) in a large cohort of primary care patients with gout, since there have been no such large studi... Read More about Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink.

Maximising response from GPs to questionnaire surveys: do length or incentives make a difference? (2015)
Journal Article
Roddy. (2015). Maximising response from GPs to questionnaire surveys: do length or incentives make a difference?. BMC medical research methodology, 3 -?. https://doi.org/10.1186/1471-2288-15-3

BACKGROUND: General Practitioners (GPs) respond poorly to postal surveys. Consequently there is potential for reduced data quality and bias in the findings. In general population surveys, response to postal questionnaires may be improved by reducing... Read More about Maximising response from GPs to questionnaire surveys: do length or incentives make a difference?.

Bisphosphonates and Risk of Acute Pseudogout: A Case-Control Study in the Clinical Practice Research Datalink (CPRD). (2014)
Presentation / Conference
Muller, S., Paskins, Z., Hider, S., Mallen, C., Roddy, E., & Bucknall, M. (2014, November). Bisphosphonates and Risk of Acute Pseudogout: A Case-Control Study in the Clinical Practice Research Datalink (CPRD). Poster presented at 2014 ACR/ARHP Annual Meeting, Boston, MA, usa

Background/Purpose: Acute pseudogout is the most dramatic clinical manifestation of calcium pyrophosphate crystal deposition (CPPD). CPPD is most commonly sporadic and age-related but can rarely occur secondary to metabolic diseases or a familial tra... Read More about Bisphosphonates and Risk of Acute Pseudogout: A Case-Control Study in the Clinical Practice Research Datalink (CPRD)..

Demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis: cross-sectional findings from the Clinical Assessment Study of the Foot (2014)
Journal Article
Menz, H., Roddy, E., Marshall, M., Thomas, M., Rathod, T., Myers, H., …Peat, G. (2015). Demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis: cross-sectional findings from the Clinical Assessment Study of the Foot. Osteoarthritis and Cartilage, 23(1), 77 -82. https://doi.org/10.1016/j.joca.2014.10.007

OBJECTIVE: To explore demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis (OA) (First MTPJ OA). DESIGN: Adults aged =50 years registered with four general practices were mailed a He... Read More about Demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis: cross-sectional findings from the Clinical Assessment Study of the Foot.

Sleep Apnea and Risk of Incident Gout: A Population-Based Body-Mass Index Matched Cohort Study. (2014)
Journal Article
Roddy. (2014). Sleep Apnea and Risk of Incident Gout: A Population-Based Body-Mass Index Matched Cohort Study. Arthritis and Rheumatology, S72 - S72. https://doi.org/10.1002/art.39330

Objective Sleep apnea is associated with hyperuricemia owing to hypoxia-induced nucleotide turnover. We undertook this study to assess the relationship between incident sleep apnea and the risk of incident gout. Methods Using data from The Healt... Read More about Sleep Apnea and Risk of Incident Gout: A Population-Based Body-Mass Index Matched Cohort Study..

Risk of vascular events in patients with polymyalgia rheumatica. (2014)
Journal Article
Hancock, A. T., Mallen, C. D., Muller, S., Belcher, J., Roddy, E., Helliwell, T., & Hider, S. L. (2014). Risk of vascular events in patients with polymyalgia rheumatica. Canadian Medical Association Journal, 186(13), E495 - E501. https://doi.org/10.1503/cmaj.140266

BACKGROUND: Polymyalgia rheumatica is one of the most common inflammatory rheumatologic conditions in older adults. Other inflammatory rheumatologic disorders are associated with an excess risk of vascular disease. We investigated whether polymyalgia... Read More about Risk of vascular events in patients with polymyalgia rheumatica..

Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK Clinical Practice Research Datalink (2014)
Journal Article
Clarson, L. E., Hider, S. L., Belcher, J., Heneghan, C., Roddy, E., & Mallen, C. D. (2014). Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, 74(4), 642-647. https://doi.org/10.1136/annrheumdis-2014-205252

Objectives To determine whether gout increases risk of incident coronary heart disease (CHD), cerebrovascular (CVD) and peripheral vascular disease (PVD) in a large cohort of primary care patients with gout, since there have been no such large studie... Read More about Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK Clinical Practice Research Datalink.

A multicentre, pragmatic, parallel group, randomised controlled trial to compare the clinical and cost-effectiveness of three physiotherapy-led exercise interventions for knee osteoarthritis in older adults: the BEEP trial protocol (ISRCTN: 93634563). (2014)
Journal Article
Healey, E. L., Holden, M. A., Nicholls, E., Whitehurst, D. G., Foster, N. E., Jowett, S., …Hay, E. M. (2014). A multicentre, pragmatic, parallel group, randomised controlled trial to compare the clinical and cost-effectiveness of three physiotherapy-led exercise interventions for knee osteoarthritis in older adults: the BEEP trial protocol (ISRCTN: 93634563). BMC Musculoskeletal Disorders, 15, Article 254

BACKGROUND: Exercise is consistently recommended for older adults with knee pain related to osteoarthritis. However, the effects from exercise are typically small and short-term, likely linked to insufficient individualisation of the exercise program... Read More about A multicentre, pragmatic, parallel group, randomised controlled trial to compare the clinical and cost-effectiveness of three physiotherapy-led exercise interventions for knee osteoarthritis in older adults: the BEEP trial protocol (ISRCTN: 93634563)..