Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA
(2018)
Journal Article
Yokoyama, M., Stevens, E., Laabei, M., Bacon, L., Heesom, K., Bayliss, S., …Massey, R. C. (2018). Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA. Genome Biology, 19, Article 94. https://doi.org/10.1186/s13059-018-1469-2
Background Fitness costs imposed on bacteria by antibiotic resistance mechanisms are believed to hamper their dissemination. The scale of these costs is highly variable. Some, including resistance of Staphylococcus aureus to the clinically important... Read More about Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA.