Human umbilical cord mesenchymal stromal cells do not evoke an immune response in the partial medial meniscectomy murine model of osteoarthritis

Perry, J.; Mennan, C.; McCarthy, H.S.; Bou-Gharios, G.; Hof, R. van 't; Milner, P.; Wright, K.T.; Roberts, S.

doi:10.1016/j.joca.2019.02.468

All Outputs (3)

Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential (2019)
Journal Article
Mennan, C., Garcia, J., McCarthy, H., Owen, S., Perry, J., Wright, K., …Roberts, S. (2019). Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential. Cartilage, 10(4), 467-479. https://doi.org/10.1177/1947603518769714

Objective To assess the phenotype of human articular chondrocytes cultured in normoxia (21% O2) or continuous hypoxia (2% O2). Design Chondrocytes were extracted from patients undergoing total knee replacement (n = 5) and cultured in ~21% (normo... Read More about Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential.

Combined Autologous Chondrocyte and Bone Marrow Mesenchymal Stromal Cell Implantation in the Knee: An 8-year Follow Up of Two First-In-Man Cases (2019)
Journal Article
Wang, J., Wright, K., Perry, J., Tins, B., Hopkins, T., Hulme, C., …Richardson, J. (2019). Combined Autologous Chondrocyte and Bone Marrow Mesenchymal Stromal Cell Implantation in the Knee: An 8-year Follow Up of Two First-In-Man Cases. Cell Transplantation, 28(7), 924 - 931. https://doi.org/10.1177/0963689719845328

Autologous chondrocyte implantation (ACI) has been used to treat cartilage defects for >20 years, with promising clinical outcomes. Here, we report two first-in-man cases (patient A and B) treated with combined autologous chondrocyte and bone marrow... Read More about Combined Autologous Chondrocyte and Bone Marrow Mesenchymal Stromal Cell Implantation in the Knee: An 8-year Follow Up of Two First-In-Man Cases.

Human umbilical cord mesenchymal stromal cells do not evoke an immune response in the partial medial meniscectomy murine model of osteoarthritis (2019)
Journal Article
Perry, J., Mennan, C., McCarthy, H., Bou-Gharios, G., Hof, R. V. '., Milner, P., …Roberts, S. (2019). Human umbilical cord mesenchymal stromal cells do not evoke an immune response in the partial medial meniscectomy murine model of osteoarthritis. Osteoarthritis and Cartilage, 27(S1), S438-S439. https://doi.org/10.1016/j.joca.2019.02.468