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Characteristics and Outcomes of Patients Who Underwent Coronary Atherectomy in Centers With and Without On-Site Cardiac Surgery (2023)
Journal Article
Dafaalla, M., Rashid, M., Moledina, S., Kinnaird, T., Ludman, P., Curzen, N., …Mamas, M. A. (in press). Characteristics and Outcomes of Patients Who Underwent Coronary Atherectomy in Centers With and Without On-Site Cardiac Surgery. American Journal of Cardiology, 204, 242-248. https://doi.org/10.1016/j.amjcard.2023.07.073

We aimed to describe the clinical characteristics and outcomes of patients who underwent atherectomy at the time of percutaneous coronary intervention in centers with on-site surgical centers (SCs) versus nonsurgical centers (NSCs)... Read More about Characteristics and Outcomes of Patients Who Underwent Coronary Atherectomy in Centers With and Without On-Site Cardiac Surgery.

Outcomes of ST elevation myocardial infarction in patients with cancer: a nationwide study (2023)
Journal Article
Dafaalla, M., Abdel-Qadir, H., Gale, C. P., Sun, L., López-Fernández, T., Miller, R. J. H., …Mamas, M. A. (2023). Outcomes of ST elevation myocardial infarction in patients with cancer: a nationwide study. European Heart Journal - Quality of Care and Clinical Outcomes, 9(8), 806-817. https://doi.org/10.1093/ehjqcco/qcad012

AIMS: To assess processes of care and clinical outcomes in cancer patients with ST elevation myocardial infarction (STEMI) according to cancer type. METHODS: This is a national population-based study of patients admitted with STEMI in England and Wal... Read More about Outcomes of ST elevation myocardial infarction in patients with cancer: a nationwide study.

Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis. (2022)
Journal Article
Nolan. (2022). Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis. Frontiers in Cardiovascular Medicine, 1022415 - ?. https://doi.org/10.3389/fcvm.2022.1022415

BACKGROUND: Old age and the presence of aortic stenosis are associated with the unfolding of the intrathoracic aorta. This may result in increased difficulties navigating catheters from the right compared to the left radial approach. OBJECTIVE: To in... Read More about Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis..

Routine Pressure Wire Assessment Versus Conventional Angiography in the Management of Patients With Coronary Artery Disease: The RIPCORD 2 Trial (2022)
Journal Article
Stables, R. H., Mullen, L. J., Elguindy, M., Nicholas, Z., Aboul-Enien, Y. H., Kemp, I., …Curzen, N. (2022). Routine Pressure Wire Assessment Versus Conventional Angiography in the Management of Patients With Coronary Artery Disease: The RIPCORD 2 Trial. Circulation, 146(9), 687-698. https://doi.org/10.1161/CIRCULATIONAHA.121.057793

Background: Measurement of fractional flow reserve (FFR) has an established role in guiding percutaneous coronary intervention. We tested the hypothesis that, at the stage of diagnostic invasive coronary angiography, systematic FFR-guided assessment... Read More about Routine Pressure Wire Assessment Versus Conventional Angiography in the Management of Patients With Coronary Artery Disease: The RIPCORD 2 Trial.

Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial. (2022)
Journal Article
Nolan. (2022). Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial. JACC: Cardiovascular Interventions, 1191 - 1201. https://doi.org/10.1016/j.jcin.2022.04.032

BACKGROUND: Currently, transradial access (TRA) is the recommended access for coronary procedures because of increased safety, with radial artery occlusion (RAO) being its most frequent complication, which will increasingly affect patients undergoing... Read More about Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial..

Temporal patterns, characteristics, and predictors of clinical outcomes in patients undergoing percutaneous coronary intervention for stent thrombosis. (2022)
Journal Article
Mohamed, M. O., Sirker, A., Chieffo, A., Avanzas, P., Nolan, J., Rashid, M., …Mamas, M. (2022). Temporal patterns, characteristics, and predictors of clinical outcomes in patients undergoing percutaneous coronary intervention for stent thrombosis. EuroIntervention, 18(9), https://doi.org/10.4244/EIJ-D-22-00049

BACKGROUND: There are limited data on the outcomes of percutaneous coronary intervention (PCI) following stent thrombosis (ST) and differences exist based on timing. AIMS: Our aim was to study the rates of PCI procedures for an ST indication among al... Read More about Temporal patterns, characteristics, and predictors of clinical outcomes in patients undergoing percutaneous coronary intervention for stent thrombosis..

Impact of pre-existing vascular disease on clinical outcomes (2022)
Journal Article
Weight, N., Moledina, S., Zoccai, G. B., Zaman, S., Smith, T., Siller-Matula, J., …Mamas, M. A. (2022). Impact of pre-existing vascular disease on clinical outcomes. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcac026

AIMS: Little is known about the outcomes and processes of care of patients with non ST-segment myocardial infarction (NSTEMI) who present with 'polyvascular' disease. METHODS AND RESULTS: We analysed 287,279 NSTEMI patients using the Myocardial Infar... Read More about Impact of pre-existing vascular disease on clinical outcomes.

Addressing disparities of care in non-ST-segment elevation myocardial infarction (NSTEMI) patients without standard modifiable risk factors: insights from a nationwide cohort study (2021)
Journal Article
Rashid, Mamas, & Nolan. (2021). Addressing disparities of care in non-ST-segment elevation myocardial infarction (NSTEMI) patients without standard modifiable risk factors: insights from a nationwide cohort study. European Journal of Preventive Cardiology, 1084-1092. https://doi.org/10.1093/eurjpc/zwab200

Background: The importance of standard modifiable cardiovascular risk factors (SMuRFs) in preventing non-ST segment myocardial infarction (NSTEMI) is established. However, NSTEMI may present in the absence of SMuRFs, and little is known about their o... Read More about Addressing disparities of care in non-ST-segment elevation myocardial infarction (NSTEMI) patients without standard modifiable risk factors: insights from a nationwide cohort study.

Intravascular imaging-guided intracoronary lithotripsy: First real-world experience (2021)
Journal Article
Sinclair, H., Fan, L., Fahy, E., Shahid, F., Ratib, K., Nolan, J., …Ahmed, J. (2021). Intravascular imaging-guided intracoronary lithotripsy: First real-world experience. Health Science Reports, 4(3), Article e307. https://doi.org/10.1002/hsr2.307

Background and Aims: Coronary calcification remains a significant challenge for the contemporary interventional cardiologist. We aim to describe the use of intravascular lithotripsy (IVL) in a range of real-world settings. Methods: A retrospective tw... Read More about Intravascular imaging-guided intracoronary lithotripsy: First real-world experience.

Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Aortic Stenosis in England. (2021)
Journal Article
Mamas, & Nolan. (2021). Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Aortic Stenosis in England. Circulation: Cardiovascular Interventions, 532-543. https://doi.org/10.1161/CIRCINTERVENTIONS.120.010413

Background: Aortic stenosis requires timely treatment with either surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR). This study aimed to investigate the indirect impact of coronavirus disease 2019 (COVID-19) o... Read More about Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Aortic Stenosis in England..

Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients (2021)
Journal Article
Rashid, M., Shoaib, A., Mohamed, M., Curzen, N., Ludman, P., Zaman, A., …Mamas, M. A. (2021). Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients. Catheterization and Cardiovascular Interventions, 99(1), 74-84. https://doi.org/10.1002/ccd.29691

OBJECTIVE: To compare the clinical characteristics and outcomes in patients with stable angina who have undergone chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in native arteries with or without prior coronary artery bypass g... Read More about Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients.

Evidence-based arterial access site practice in patients with acute coronary syndromes: Has SAFARI-STEMI changed the landscape? (2021)
Journal Article
Nagaraja, V., Rao, S. V., George, S., Mamas, M., & Nolan, J. (2021). Evidence-based arterial access site practice in patients with acute coronary syndromes: Has SAFARI-STEMI changed the landscape?. Catheterization and Cardiovascular Interventions, 97(7), 1417 - 1421. https://doi.org/10.1002/ccd.29684

Key Points Access site practice in acute coronary syndrome (ACS) has been extensively investigated with the data favoring a radial approach. SAFARI‐STEMI does not change the recommendation to use radial access in most patients due to methodological i... Read More about Evidence-based arterial access site practice in patients with acute coronary syndromes: Has SAFARI-STEMI changed the landscape?.

Radial First in ST-Segment-Elevation Myocardial Infarction (2021)
Journal Article
Jolly, S. S., & Nolan, J. (2021). Radial First in ST-Segment-Elevation Myocardial Infarction. Circulation: Cardiovascular Interventions, 14(3), Article ARTN e010595. https://doi.org/10.1161/CIRCINTERVENTIONS.121.010595

As young interventionalists, we recall randomizing patients with ST-segment–elevation myocardial infarction (STEMI) into studies such as the RIVAL trial (the Radial Versus Femoral Access for Coronary Angiography and Intervention) and struggling with... Read More about Radial First in ST-Segment-Elevation Myocardial Infarction.

Vascular complications associated with intraaortic balloon pump supported percutaneous coronary intervention (PCI) and clinical outcomes from the British Cardiovascular Intervention Society National PCI Database. (2021)
Journal Article
Kinnaird, T., Anderson, R., Gallagher, S., Sharp, A. S. P., Farooq, V., Ludman, P., …Mamas, M. (2021). Vascular complications associated with intraaortic balloon pump supported percutaneous coronary intervention (PCI) and clinical outcomes from the British Cardiovascular Intervention Society National PCI Database. Catheterization and Cardiovascular Interventions, 98(1), E53-E61. https://doi.org/10.1002/ccd.29549

INTRODUCTION: The impact of a vascular complication (VC) in the setting of intraaortic balloon pump (IABP) supported PCI on clinical outcomes is unclear. METHODS: Using data from the BCIS National PCI Database, multivariate logistic regression was us... Read More about Vascular complications associated with intraaortic balloon pump supported percutaneous coronary intervention (PCI) and clinical outcomes from the British Cardiovascular Intervention Society National PCI Database..

Outcomes of COVID-19 Positive Acute Coronary Syndrome Patients; a multisource Electronic Healthcare Records Study from England. (2021)
Journal Article
Rashid, M., Wu, J., Timmis, A., Curzen, N., Clarke, S., Zaman, A., …Mamas, M. A. (2021). Outcomes of COVID-19 Positive Acute Coronary Syndrome Patients; a multisource Electronic Healthcare Records Study from England. Journal of Internal Medicine, 290(1), 88-100. https://doi.org/10.1111/joim.13246

BACKGROUND: Patients with underlying cardiovascular disease and Coronavirus disease 2019 (COVID-19) infection are at increased risk of morbidity and mortality. OBJECTIVES: This study was designed to characterise the presenting profile and outcomes... Read More about Outcomes of COVID-19 Positive Acute Coronary Syndrome Patients; a multisource Electronic Healthcare Records Study from England..

Comparison of distal radial access versus standard transradial access in patients with smaller diameter radial Arteries(The distal radial versus transradial access in small transradial ArteriesStudy: D.A.T.A - S.T.A.R study). (2021)
Journal Article
Chugh, Y., Sasidhar Kanaparthy, N., Piplani, S., Chugh, S., Shroff, A., Vidovich, M., …Kumar Chugh, S. (2021). Comparison of distal radial access versus standard transradial access in patients with smaller diameter radial Arteries(The distal radial versus transradial access in small transradial ArteriesStudy: D.A.T.A - S.T.A.R study). Indian Heart Journal, 73(1), 26 - 34. https://doi.org/10.1016/j.ihj.2020.11.002

AIMS: To evaluate safety and efficacy of distal right radial access (DRRA) compared to right radial access (RRA), for coronary procedures, in patients with smaller diameter radial arteries (SDRA) (radial artery diameter (RAD) 

Cost of coronary syndrome treated with percutaneous coronary intervention and 30-day unplanned readmission in the United States (2021)
Journal Article
Nolan, J., Mamas, M., Kwok, C. S., Amin, A. P., Shah, B., Kinnaird, T., …Bagur, R. (2021). Cost of coronary syndrome treated with percutaneous coronary intervention and 30-day unplanned readmission in the United States. Catheterization and Cardiovascular Interventions, 97(1), 80-93. https://doi.org/10.1002/ccd.28660

Objectives: This study aimed to examine the cost of coronary syndrome treated with percutaneous coronary intervention (PCI) and 30-day unplanned readmissions. Background: There is limited understanding of the hospital cost of index PCI and 30-day... Read More about Cost of coronary syndrome treated with percutaneous coronary intervention and 30-day unplanned readmission in the United States.

Radiation protection in the cardiac catheterisation lab: best practice (2020)
Journal Article
Roguin, A., & Nolan, J. (2021). Radiation protection in the cardiac catheterisation lab: best practice. Heart, 107(1), 76-82. https://doi.org/10.1136/heartjnl-2019-316369

Occupational doses of radiation in cardiac procedures guided by fluoroscopy are the highest registered among medical staff using X-rays.1–5 Electrophysiologists and interventional cardiologists are the group with the highest exposure. Patient and ope... Read More about Radiation protection in the cardiac catheterisation lab: best practice.

Clinical Characteristics and Outcomes From Percutaneous Coronary Intervention of Last Remaining Coronary Artery: An Analysis From the British Cardiovascular Intervention Society Database. (2020)
Journal Article
Shoaib, A., Rashid, M., Kontopantelis, E., Sharp, A., Fahy, E. F., Nolan, J., …Mamas, M. A. (2020). Clinical Characteristics and Outcomes From Percutaneous Coronary Intervention of Last Remaining Coronary Artery: An Analysis From the British Cardiovascular Intervention Society Database. Circulation: Cardiovascular Interventions, 13(9), Article e009049. https://doi.org/10.1161/CIRCINTERVENTIONS.120.009049

BACKGROUND: Patients with complex high-risk coronary anatomy, such as those with a last remaining patent vessel (LRPV), are increasingly revascularized with percutaneous coronary intervention (PCI) in contemporary practice. There are limited data on... Read More about Clinical Characteristics and Outcomes From Percutaneous Coronary Intervention of Last Remaining Coronary Artery: An Analysis From the British Cardiovascular Intervention Society Database..