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216 Characteristics of patients with prevalent giant cell arteritis in UK primary care (2019)
Journal Article
Twomlow, E. L., Prior, J. A., Mackie, S. L., Helliwell, T., Hider, S. L., Belcher, J., …Mallen, C. D. (2019). 216 Characteristics of patients with prevalent giant cell arteritis in UK primary care. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez107.032

Background: Giant cell arteritis (GCA) is a rare, but serious condition affecting older people. Prompt diagnosis remains challenging due to non-specific presentations. Furthermore, there are marked variations in GP referral and management approaches.... Read More about 216 Characteristics of patients with prevalent giant cell arteritis in UK primary care.

INCREASED RISK OF SELF-HARM IN PATIENTS WITH OSTEOPOROSIS: A UK POPULATION STUDY (2018)
Presentation / Conference
Prior, J., Whittle, R., Abdul-Sultan, A., Chew-Graham, C., Sumathipala, A., Sheperd, T., …Paskins, Z. (2018, December). INCREASED RISK OF SELF-HARM IN PATIENTS WITH OSTEOPOROSIS: A UK POPULATION STUDY. Poster presented at Osteoporosis Conference 2018, Birmingham, UK

Background: Prevention of self-harm, as a key risk factor for suicide, is an international public health priority. The World Health Organization recommends that clinicians should assess the potential for self-harm in patients in high-risk groups e.g.... Read More about INCREASED RISK OF SELF-HARM IN PATIENTS WITH OSTEOPOROSIS: A UK POPULATION STUDY.

Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies (2018)
Journal Article
Evans, P. L., Prior, J. A., Belcher, J., Mallen, C., Hay, C. A., & Roddy, E. (2018). Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies. Arthritis Research and Therapy, 20, Article 136. https://doi.org/10.1186/s13075-018-1612-1

BACKGROUND: Gout treatment remains suboptimal. Identifying populations at risk of developing gout may provide opportunities for prevention. Our aim was to assess the risk of incident gout associated with obesity, hypertension and diuretic use. METHOD... Read More about Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies.

AB0212 Diagnostic delay for rheumatoid arthritis: a systematic review (2018)
Presentation / Conference
Hay, C., Prior, J., Scott, I., Raza, K., Hider, S., & Mallen, C. (2018, June). AB0212 Diagnostic delay for rheumatoid arthritis: a systematic review. Paper presented at Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, Netherlands

Background Rheumatoid arthritis (RA) is a common inflammatory condition, affecting 1% of the population and causing pain, stiffness and swelling, leading to significant disability and loss of function[.1 Delays in the diagnosis and treatment of RA ca... Read More about AB0212 Diagnostic delay for rheumatoid arthritis: a systematic review.

Challenges of diagnosis and management of giant cell arteritis in general practice: a multimethods study (2018)
Journal Article
Helliwell, T., Muller, S., Hider, S. L., Prior, J. A., Richardson, J. C., & Mallen, C. D. (2018). Challenges of diagnosis and management of giant cell arteritis in general practice: a multimethods study. BMJ Open, 8(2), Article e019320. https://doi.org/10.1136/bmjopen-2017-019320

BACKGROUND: In the UK, general practitioners (GPs) are usually the first medical contact for patients with suspected giant cell arteritis (GCA). While rare, it is critical not to miss, as delayed treatment can lead to significant complications includ... Read More about Challenges of diagnosis and management of giant cell arteritis in general practice: a multimethods study.

Possible giant cell arteritis symptoms are common in newly diagnosed patients with Polymyalgia Rheumatica: results from an incident primary care PMR cohort (2017)
Journal Article
Masson, W., Muller, S., Whittle, R., Prior, J., Helliwell, T., Mallen, C., & Hider, S. (2017). Possible giant cell arteritis symptoms are common in newly diagnosed patients with Polymyalgia Rheumatica: results from an incident primary care PMR cohort. BMC Rheumatology, 1, Article 7. https://doi.org/10.1186/s41927-017-0007-2

Background: To examine the frequency of possible giant cell arteritis (GCA) symptoms (including headache, temporal/scalp tenderness, jaw claudication and visual symptoms) in newly diagnosed polymyalgia rheumatica (PMR) patients in UK primary care. Me... Read More about Possible giant cell arteritis symptoms are common in newly diagnosed patients with Polymyalgia Rheumatica: results from an incident primary care PMR cohort.

What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study (2017)
Journal Article
Liddle, J., Bartlam, R., Mallen, C. D., Mackie, S. L., Prior, J. A., Helliwell, T., & Richardson, J. C. (2017). What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study. BMJ Open, 7(8), e017073 -?. https://doi.org/10.1136/bmjopen-2017-017073

OBJECTIVES: Clinical management of giant cell arteritis (GCA) involves balancing the risks and burdens arising from the disease with those arising from treatment, but there is little research on the nature of those burdens. We aimed to explore the im... Read More about What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study.

Diagnostic delay for giant cell arteritis – a systematic review and meta-analysis (2017)
Journal Article
Prior, J. A., Ranjbar, H., Belcher, J., Mackie, S. L., Helliwell, T., Liddle, J., & Mallen, C. D. (2017). Diagnostic delay for giant cell arteritis – a systematic review and meta-analysis. BMC Medicine, 15, Article 120. https://doi.org/10.1186/s12916-017-0871-z

BACKGROUND: Giant cell arteritis (GCA), if untreated, can lead to blindness and stroke. The study's objectives were to (1) determine a new evidence-based benchmark of the extent of diagnostic delay for GCA and (2) examine the role of GCA-specific cha... Read More about Diagnostic delay for giant cell arteritis – a systematic review and meta-analysis.

Association between characteristics of pain and stiffness and the functional status of patients with incident polymyalgia rheumatica from primary care (2017)
Journal Article
Cawley, A., Prior, J., Muller, S., Helliwell, T., Hider, S., Dasgupta, B., …Mallen, C. (2017). Association between characteristics of pain and stiffness and the functional status of patients with incident polymyalgia rheumatica from primary care. Clinical Rheumatology, 37(6), 1639-1644. https://doi.org/10.1007/s10067-017-3730-6

This paper aims to examine the relationship between different characteristics of pain and stiffness and the functional status of patients with newly diagnosed polymyalgia rheumatica (PMR). Baseline analysis of an inception cohort study was conducted.... Read More about Association between characteristics of pain and stiffness and the functional status of patients with incident polymyalgia rheumatica from primary care.

SAT0708 Symptoms indicative of inflammatory arthritis are common in the primary care population: findings from the symptoms in persons at risk of rheumatoid arthritis survey (2017)
Presentation / Conference
Hider, S., Muller, S., Prior, J., Helliwell, T., Schaardenburg, D. V., Mil, A. V. D. H., …Mallen, C. (2017, June). SAT0708 Symptoms indicative of inflammatory arthritis are common in the primary care population: findings from the symptoms in persons at risk of rheumatoid arthritis survey. Paper presented at Annual European Congress of Rheumatology, 14–17 June, 2017

Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care (2017)
Journal Article
Barnett, L. A., Prior, J. A., Kadam, U. T., & Jordan, K. P. (2017). Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care. BMJ Open, 7(5), Article e015857. https://doi.org/10.1136/bmjopen-2017-015857

OBJECTIVE: To determine characteristics associated with monthly chest pain and shortness of breath (SoB) during activity in cardiovascular disease (CVD) and trajectories of these symptoms over 10 months. STUDY DESIGN AND SETTING: Baseline questionnai... Read More about Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care.

Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective (2017)
Journal Article
Mallen, Prior, Roddy, & Muller. (2017). Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective. Revue du Rhumatisme, 84(5), 423-429. https://doi.org/10.1016/j.rhum.2017.05.004

Objectifs Déterminer la prévalence de l’anxiété et de la dépression dans le contexte de la goutte, examiner les liens entre certaines caractéristiques de la goutte et ces comorbidités et identifier le rôle de l’allopurinol dans ces relations. Mét... Read More about Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective.

Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study (2016)
Journal Article
Walsh, C. P., Prior, J., Chandratre, P., Belcher, J., Mallen, C., & Roddy, E. (2016). Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study. BMC Musculoskeletal Disorders, 17, Article 394. https://doi.org/10.1186/s12891-016-1252-z

Background Patients’ perceptions of their illness are dynamic and can directly influence aspects of management. Our aim was to examine the illness perceptions of gout patients in UK primary care and associations with allopurinol use. Methods A h... Read More about Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study.

Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study. (2016)
Report
Ahmed, N., Prior, J., Chen, Y., Hayward, R., Mallen, C., & Hider, S. (2016). Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study

The aim of this study is to compare the prevalence of cardiovascular (CVD)-related comorbidities in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) or psoriasis (Ps) in UK primary care against matched cohorts. Matched retrospecti... Read More about Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study..

DIAGNOSTIC DELAY FOR GIANT CELL ARTERITIS (GCA). A SYSTEMATIC REVIEW AND META-ANALYSIS (2016)
Journal Article
Prior, J. A., Ranjbar, H., Belcher, J., Mackie, S., & Mallen, C. D. (2016). DIAGNOSTIC DELAY FOR GIANT CELL ARTERITIS (GCA). A SYSTEMATIC REVIEW AND META-ANALYSIS. Annals of the Rheumatic Diseases, 75(S2), 1092-1092. https://doi.org/10.1136/annrheumdis-2016-eular.2639

Background The diagnosis of giant cell arteritis (GCA) remains difficult, with patients often presenting with non-specific and atypical symptoms. Such ambiguity can lead to delays in the diagnosis of GCA, which in-turn may result in the patient exper... Read More about DIAGNOSTIC DELAY FOR GIANT CELL ARTERITIS (GCA). A SYSTEMATIC REVIEW AND META-ANALYSIS.

Gout characteristics associate with depression, but not anxiety, in primary care: Baseline findings from a prospective cohort study (2016)
Journal Article
Prior, J. A., Mallen, C., Chandratre, P., Muller, S., Richardson, J., & Roddy, E. (2016). Gout characteristics associate with depression, but not anxiety, in primary care: Baseline findings from a prospective cohort study. Joint Bone Spine, 83(5), 553-558. https://doi.org/10.1016/j.jbspin.2015.10.008

OBJECTIVES: To determine the prevalence of anxiety and depression in gout, examine associations between gout characteristics and these comorbidities and determine the role of allopurinol in any such relationships. METHOD: As part of a prospective coh... Read More about Gout characteristics associate with depression, but not anxiety, in primary care: Baseline findings from a prospective cohort study.