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All Outputs (20)

Designing a primary care pharmacist-led review for people treated with opioids for persistent pain: a multi-method qualitative study (2024)
Journal Article
Woodcock, C., Cornwall, N., Dikomitis, L., Harrisson, S. A., White, S., Helliwell, T., …Jinks, C. (2024). Designing a primary care pharmacist-led review for people treated with opioids for persistent pain: a multi-method qualitative study. British Journal of General Practice Open (BJGP Open), Article BJGPO.2023.0221. https://doi.org/10.3399/BJGPO.2023.0221

Background Opioids are frequently prescribed for persistent non-cancer pain despite limited evidence of long-term effectiveness and risk of harm. Evidence-based interventions to address inappropriate opioid prescribing are lacking. Aim To explore... Read More about Designing a primary care pharmacist-led review for people treated with opioids for persistent pain: a multi-method qualitative study.

Hearing the patient voice for persistent pain intervention development: Recommendations for using a bespoke online discussion forum for qualitative data collection (2024)
Journal Article
Woodcock, C., Cornwall, N., Harrisson, S., Jinks, C., Buttery, A., Ashworth, J., …Dikomitis, L. (in press). Hearing the patient voice for persistent pain intervention development: Recommendations for using a bespoke online discussion forum for qualitative data collection. British Journal of Pain,

We discuss a bespoke online discussion forum as an innovative method for qualitative data collection in the context of developing an intervention for patients prescribed opioids for persistent pain. We discuss the following key areas: planning and de... Read More about Hearing the patient voice for persistent pain intervention development: Recommendations for using a bespoke online discussion forum for qualitative data collection.

Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. (2024)
Journal Article
Muller, S., Bailey, J., Bajpai, R., Helliwell, T., Harrisson, S. A., Whittle, R., …Ashworth, J. (in press). Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. PAIN, https://doi.org/10.1097/j.pain.0000000000003239

Growing evidence from pharmacovigilance data and postmortem toxicology reports highlights the misuse potential of gabapentinoids. This study aimed to investigate the risk of serious adverse outcomes (drug misuse, overdose, major trauma), and their ri... Read More about Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study..

Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development (2023)
Journal Article
Cornwall, N., Woodcock, C., Ashworth, J., Harrisson, S. A., Dikomitis, L., White, S., …on behalf of the PROMPPT team. (2023). Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development. British Journal of Pain, https://doi.org/10.1177/20494637231221688

Introduction Regular review of patients prescribed opioids for persistent non-cancer pain (PCNP) is recommended but not routinely undertaken. The PROMPPT (Proactive clinical Review of patients taking Opioid Medicines long-term for persistent Pain le... Read More about Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development.

The Pain Anxiety Symptom Scale: Initial development and evaluation of four and eight item short forms. (2023)
Journal Article
Vowles, K. E., Kruger, E. S., Bailey, R. W., Ashworth, J., Hickman, J., Sowden, G., & McCracken, L. M. (in press). The Pain Anxiety Symptom Scale: Initial development and evaluation of four and eight item short forms. The Journal of Pain, 25(1), 176-186. https://doi.org/10.1016/j.jpain.2023.08.001

Elevated levels of anxiety in relation to chronic pain have been consistently associated with greater distress and disability. Thus, accurate measurement of pain-related anxiety is an important requirement in modern pain services. The Pain Anxiety Sy... Read More about The Pain Anxiety Symptom Scale: Initial development and evaluation of four and eight item short forms..

Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study (2023)
Journal Article
Ashworth, J., Bajpai, R., Muller, S., Bailey, J., Helliwell, T., Harrisson, S., …Mallen, C. (2023). Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study. The Lancet Regional Health Europe, 27, Article ARTN 100579. https://doi.org/10.1016/j.lanepe.2022.100579

Background The UK government reclassified gabapentin and pregabalin as ‘controlled drugs’ from April 2019. This study aimed to describe the trends in gabapentinoid prescribing before and immediately after reclassification, in the UK Clinical Practic... Read More about Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study.

Profiles of Pain Acceptance and Values-Based Action in the Assessment and Treatment of Chronic Pain. (2022)
Journal Article
Ashworth. (2022). Profiles of Pain Acceptance and Values-Based Action in the Assessment and Treatment of Chronic Pain. Journal of Pain, https://doi.org/10.1016/j.jpain.2022.06.005

Pain acceptance and values-based action are relevant to treatment outcomes in those with chronic pain. It is unclear if patterns of responding in these 2 behavioral processes can be used to classify patients into distinct classes at treatment onset a... Read More about Profiles of Pain Acceptance and Values-Based Action in the Assessment and Treatment of Chronic Pain..

Initial Evaluation of the Chronic Pain Acceptance Questionnaire – 2 (2020)
Journal Article
Ashworth. (2020). Initial Evaluation of the Chronic Pain Acceptance Questionnaire – 2. European Journal of Pain, https://doi.org/10.1002/ejp.1650

Greater acceptance of chronic pain is associated with lesser levels of pain-related distress and disability and better overall functioning. Pain acceptance is most often assessed using the Chronic Pain Acceptance Questionnaire (CPAQ), which includes... Read More about Initial Evaluation of the Chronic Pain Acceptance Questionnaire – 2.

Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care (2019)
Journal Article
Appleyard, T., Ashworth, J., Bedson, J., Yu, D., & Peat, G. (2019). Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care. Osteoarthritis and Cartilage, 1437-1444. https://doi.org/10.1016/j.joca.2019.06.008

Summary Objective To investigate trends in gabapentinoid prescribing in patients with osteoarthritis (OA). Methods Patients aged 40 years and over with a new OA diagnosis recorded between 1995 and 2015 were identified in the Clinical Practice Re... Read More about Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care.

The Relation of Self-Compassion to Functioning among Adults with Chronic Pain (2019)
Journal Article
Ashworth. (2019). The Relation of Self-Compassion to Functioning among Adults with Chronic Pain. European Journal of Pain, https://doi.org/10.1002/ejp.1429

Previous research has shown that self-compassion is associated with improved functioning and health outcomes among multiple chronic illnesses. However, the role of self-compassion in chronic pain-related functioning is understudied. The present study... Read More about The Relation of Self-Compassion to Functioning among Adults with Chronic Pain.

Risk of adverse events in patients prescribed long-term opioids: a cohort study in the UK Clinical Practice Research Datalink (2019)
Journal Article
Bedson, J., Chen, Y., Ashworth, J., Hayward, R. A., Dunn, K. M., & Jordan, K. P. (2019). Risk of adverse events in patients prescribed long-term opioids: a cohort study in the UK Clinical Practice Research Datalink. European Journal of Pain, 23(5), 908-922. https://doi.org/10.1002/ejp.1357

Background Long-term opioid prescribing for musculoskeletal pain is controversial due to uncertainty regarding effectiveness and safety. This study examined the risks of a range of adverse events in a large cohort of patients prescribed long-term op... Read More about Risk of adverse events in patients prescribed long-term opioids: a cohort study in the UK Clinical Practice Research Datalink.

Examining Committed Action in Chronic Pain: Further Validation and Clinical Utility of the Committed Action Questionnaire. (2016)
Journal Article
Bailey, R. W., Vowles, K. E., Witkiewitz, K., Sowden, G., & Ashworth, J. (2016). Examining Committed Action in Chronic Pain: Further Validation and Clinical Utility of the Committed Action Questionnaire. Journal of Pain, 1095-1104. https://doi.org/10.1016/j.jpain.2016.06.011

Psychosocial treatments for chronic pain conditions, such as Acceptance and Commitment Therapy, have highlighted minimizing pain avoidance behaviors and increasing engagement in valued activities as key treatment targets. In terms of salient processe... Read More about Examining Committed Action in Chronic Pain: Further Validation and Clinical Utility of the Committed Action Questionnaire..

Trends in long-term opioid prescribing in primary care patients with musculoskeletal conditions: an observational database study (2016)
Journal Article
Bedson, J., Chen, Y., Hayward, R. A., Ashworth, J., Walters, K., Dunn, K. M., & Jordan, K. P. (2016). Trends in long-term opioid prescribing in primary care patients with musculoskeletal conditions: an observational database study. PAIN, 157(7), 1525 -1531. https://doi.org/10.1097/j.pain.0000000000000557

Long-term opioids may benefit patients with chronic pain but have also been linked to harmful outcomes. In the United Kingdom, the predominant source of opioids is primary care prescription. The objective was to examine changes in the incidence, leng... Read More about Trends in long-term opioid prescribing in primary care patients with musculoskeletal conditions: an observational database study.

Preliminary Evaluation of the Values Tracker: A Two-Item Measure of Engagement in Valued Activities in Those With Chronic Pain (2015)
Journal Article
Pielech, M., Bailey, R. W., McEntee, M. L., Ashworth, J., Levell, J., Sowden, G., & Vowles, K. E. (2016). Preliminary Evaluation of the Values Tracker: A Two-Item Measure of Engagement in Valued Activities in Those With Chronic Pain. Behavior Modification, 40(1-2), 239-256. https://doi.org/10.1177/0145445515616911

Engagement in valued activities is an important outcome, particularly in treatments that aim to enhance quality of life in those with chronic conditions. The present study describes the initial evaluation of the Values Tracker (VT), a two-item measur... Read More about Preliminary Evaluation of the Values Tracker: A Two-Item Measure of Engagement in Valued Activities in Those With Chronic Pain.

Psychological Flexibility in Coping With Chronic Pain: Further Examination of the Brief Pain Coping Inventory-2 (2014)
Journal Article
Vowles, K. E., McCracken, L. M., Sowden, G., & Ashworth, J. (2014). Psychological Flexibility in Coping With Chronic Pain: Further Examination of the Brief Pain Coping Inventory-2. The Clinical Journal of Pain, 30(4), 324-330. https://doi.org/10.1097/ajp.0b013e31829ea187

Objective: The role of coping in chronic pain management is well established. One challenge to the coping approach, however, is in identifying forms of coping that reliably lead to better functioning. An emerging approach to coping is based on the... Read More about Psychological Flexibility in Coping With Chronic Pain: Further Examination of the Brief Pain Coping Inventory-2.

Acceptance and Commitment Therapy for Chronic Pain: Evidence of Mediation and Clinically Significant Change Following an Abbreviated Interdisciplinary Program of Rehabilitation (2013)
Journal Article
Vowles, K. E., Witkiewitz, K., Sowden, G., & Ashworth, J. (2014). Acceptance and Commitment Therapy for Chronic Pain: Evidence of Mediation and Clinically Significant Change Following an Abbreviated Interdisciplinary Program of Rehabilitation. Journal of Pain, 15(1), 101-113. https://doi.org/10.1016/j.jpain.2013.10.002

There is an emerging body of evidence regarding interdisciplinary acceptance and commitment therapy in the rehabilitative treatment of chronic pain. This study evaluated the reliability and clinical significance of change following an open trial that... Read More about Acceptance and Commitment Therapy for Chronic Pain: Evidence of Mediation and Clinically Significant Change Following an Abbreviated Interdisciplinary Program of Rehabilitation.

Opioid use among low back pain patients in primary care: Is opioid prescription associated with disability at 6-month follow-up? (2013)
Journal Article
Ashworth, J., Green, D. J., Dunn, K. M., & Jordan, K. P. (2013). Opioid use among low back pain patients in primary care: Is opioid prescription associated with disability at 6-month follow-up?. PAIN, 1038 - 1044. https://doi.org/10.1016/j.pain.2013.03.011

Opioid prescribing for chronic noncancer pain is increasing, but there is limited knowledge about longer-term outcomes of people receiving opioids for conditions such as back pain. This study aimed to explore the relationship between prescribed opioi... Read More about Opioid use among low back pain patients in primary care: Is opioid prescription associated with disability at 6-month follow-up?.

Prognostic factors in non-surgically treated sciatica: a systematic review (2011)
Journal Article
Ashworth, J., Konstantinou, K., & Dunn, K. M. (2011). Prognostic factors in non-surgically treated sciatica: a systematic review. BMC Musculoskeletal Disorders, 208 - ?. https://doi.org/10.1186/1471-2474-12-208

BACKGROUND: When present sciatica is considered an obstacle to recovery in low back pain patients, yet evidence is limited regarding prognostic factors for persistent disability in this patient group. The aim of this study is to describe and summaris... Read More about Prognostic factors in non-surgically treated sciatica: a systematic review.