All Outputs (34)

Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy (2019)
Journal Article
Sim. (2019). Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy. Theoretical Medicine and Bioethics, 40, 83 -101. https://doi.org/10.1007/s11017-019-09481-0

Outcome-adaptive randomization (OAR) has been proposed as a corrective to certain ethical difficulties inherent in the traditional randomized clinical trial (RCT) using fixed-ratio randomization. In particular, it has been suggested that OAR redresse... Read More about Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy.

SAT-374 Adrenal Incidentaloma Management: Development of a Cost-Effectiveness Tool (2019)
Journal Article
Hanna, F. W. F., Issa, B., Lea, S., George, C., Golash, A., Firn, M., …Fryer, A. (2019). SAT-374 Adrenal Incidentaloma Management: Development of a Cost-Effectiveness Tool. Journal of the Endocrine Society, 3(Supplement_1), https://doi.org/10.1210/js.2019-sat-374

SAT-373 Adrenal Incidentaloma Unidentified Case Load: Are We Dealing Only with the Tip of the Iceberg? (2019)
Journal Article
Hanna, F., Issa, B., Lea, S., George, C., Golash, A., Firn, M., …Fryer, A. (2019). SAT-373 Adrenal Incidentaloma Unidentified Case Load: Are We Dealing Only with the Tip of the Iceberg?. Journal of the Endocrine Society, 3(Supplement_1), https://doi.org/10.1210/js.2019-sat-373

Can sample size in qualitative research be determined a priori? (2018)
Journal Article
Sim, J., Saunders, B., Waterfield, J., & Kingstone, T. (2018). Can sample size in qualitative research be determined a priori?. International Journal of Social Research Methodology, 5, https://doi.org/10.1080/13645579.2018.1454643

There has been considerable recent interest in methods of determining sample size for qualitative research a priori, rather than through an adaptive approach such as saturation. Extending previous literature in this area, we identify four distinct ap... Read More about Can sample size in qualitative research be determined a priori?.

Generating Individual Patient Preferences for the Treatment of Osteoarthritis Using Adaptive Choice-Based Conjoint (ACBC) Analysis. (2017)
Journal Article
Al-Omari, B., Sim, J., Croft, P., & Frisher, M. (2017). Generating Individual Patient Preferences for the Treatment of Osteoarthritis Using Adaptive Choice-Based Conjoint (ACBC) Analysis. Rheumatology and Therapy, 4, 167-182. https://doi.org/10.1007/s40744-017-0056-4

INTRODUCTION: To explore how adaptive choice-based conjoint (ACBC) analysis could contribute to shared decision-making in the treatment of individual patients with osteoarthritis (OA). METHODS: In-depth case study of three individuals randomly select... Read More about Generating Individual Patient Preferences for the Treatment of Osteoarthritis Using Adaptive Choice-Based Conjoint (ACBC) Analysis..

Acupuncture and electro-acupuncture for people diagnosed with subacromial pain syndrome: A multicentre randomized trial (2017)
Journal Article
Barlas, P., Lewis, J., & Sim, J. (2017). Acupuncture and electro-acupuncture for people diagnosed with subacromial pain syndrome: A multicentre randomized trial. European Journal of Pain, 1007-1019. https://doi.org/10.1002/ejp.1001

BACKGROUND: Musculoskeletal disorders have been identified globally as the second most common healthcare problem for 'years lived with disability', and of these shoulder conditions are amongst the most common, frequently associated with substantial p... Read More about Acupuncture and electro-acupuncture for people diagnosed with subacromial pain syndrome: A multicentre randomized trial.

Identifying patients with chronic widespread pain in primary care. (2017)
Journal Article
Mansfield, K., Sim, J., Croft, P., & Jordan, K. (2017). Identifying patients with chronic widespread pain in primary care. PAIN, 158, 110-119. https://doi.org/10.1097/j.pain.0000000000000733

Chronic widespread pain (CWP) is common in the general population. It is unclear how people reporting this problem present in primary care; they may regularly consult for regional pains without being recognized as having a generalized condition. Our... Read More about Identifying patients with chronic widespread pain in primary care..

DNA methylation at diagnosis is associated with response to disease-modifying drugs in early rheumatoid arthritis (2016)
Journal Article
Glossop, J. R., Nixon, N. B., Emes, R. D., Sim, J., Packham, J. C., Mattey, D. L., …Fryer, A. A. (2017). DNA methylation at diagnosis is associated with response to disease-modifying drugs in early rheumatoid arthritis. Epigenomics, 9(4), 419-428. https://doi.org/10.2217/epi-2016-0042

Validation and Recalibration of Two Multivariable Prognostic Models for Survival and Independence in Acute Stroke (2016)
Journal Article
Sim, J., Teece, L., Dennis, M. S., & Roffe, C. (2016). Validation and Recalibration of Two Multivariable Prognostic Models for Survival and Independence in Acute Stroke. PloS one, 11(5), Article ARTN e0153527. https://doi.org/10.1371/journal.pone.0153527

Introduction Various prognostic models have been developed for acute stroke, including one based on age and five binary variables (‘six simple variables’ model; SSVMod) and one based on age plus scores on the National Institutes of Health Stroke Sca... Read More about Validation and Recalibration of Two Multivariable Prognostic Models for Survival and Independence in Acute Stroke.

Older People’s Perceptions of Remaining Physically Active and Living With Chronic Pain (2014)
Journal Article
Moore, A. J., Richardson, J. C., Sim, J., Bernard, M., & Jordan, K. P. (2014). Older People’s Perceptions of Remaining Physically Active and Living With Chronic Pain. Qualitative Health Research, 24(6), 761-772. https://doi.org/10.1177/1049732314529663

USING ADAPTIVE CHOICE BASED CONJOINT (ACBC) ANALYSIS TO STUDY PATIENTS' PREFERENCES REGARDING PHARMACEUTICAL TREATMENT FOR OSTEOARTHRITIS (OA). (2013)
Journal Article
Al-Omari, B., Frisher, M., Croft, P., & Sim, J. (2013). USING ADAPTIVE CHOICE BASED CONJOINT (ACBC) ANALYSIS TO STUDY PATIENTS' PREFERENCES REGARDING PHARMACEUTICAL TREATMENT FOR OSTEOARTHRITIS (OA). Annals of the Rheumatic Diseases, 72,

Alternating-frequency TENS effects on experimental pain in healthy human participants: a randomized placebo-controlled trial (2013)
Journal Article
Barlas, P., Chesterton, L., Sim, J., & Claydon, L. (2013). Alternating-frequency TENS effects on experimental pain in healthy human participants: a randomized placebo-controlled trial. Clinical Journal of Pain, 533-539. https://doi.org/10.1097/ajp.0b013e318262330f

Background Transcutaneous electrical nerve stimulation (TENS) is a modality commonly used in pain management. Objectives This study investigated the hypoalgesic effects of alternating-frequency TENS (4 Hz for 3 s/110 Hz for 3 s) on pressure pain... Read More about Alternating-frequency TENS effects on experimental pain in healthy human participants: a randomized placebo-controlled trial.

Hands-on therapy interventions for upper limb motor dysfunction following stroke. (2011)
Journal Article
Winter, J., Hunter, S., Sim, J., & Crome, P. (2011). Hands-on therapy interventions for upper limb motor dysfunction following stroke. Stroke, 43(1), e1-e2. https://doi.org/10.1161/STROKEAHA.111.635573

Transcutaneous electrical nerve stimulation for the management of tennis elbow: a pragmatic randomized controlled trial: the TATE trial (ISRCTN 87141084) (2009)
Journal Article
Chesterton, L. S., van der Windt, D. A., Sim, J., Lewis, M., Mallen, C. D., Mason, E. E., …Hay, E. M. (2009). Transcutaneous electrical nerve stimulation for the management of tennis elbow: a pragmatic randomized controlled trial: the TATE trial (ISRCTN 87141084). BMC Musculoskeletal Disorders, 10(1), https://doi.org/10.1186/1471-2474-10-156