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All Outputs (8)

Continuous or intermittent? Which regiment of enteral nutrition is better for acute stroke patients? A systematic review and meta-analysis (2019)
Journal Article
Di Paolo, G., Twomlow, E., Hanna, F., Farmer, A., Lancaster, J., Sim, J., & Roffe, C. (2019). Continuous or intermittent? Which regiment of enteral nutrition is better for acute stroke patients? A systematic review and meta-analysis. https://doi.org/10.32474/OJNBD.2019.03.000163

Background and purpose: Enteral nutrition via nasogastric tube in acute stroke patients with dysphagia is an important determinant of patient outcomes. It is unclear whether intermittent or continuous feeding is more efficacious. The aim of this revi... Read More about Continuous or intermittent? Which regiment of enteral nutrition is better for acute stroke patients? A systematic review and meta-analysis.

Should treatment effects be estimated in pilot and feasibility studies? (2019)
Journal Article
Sim. (2019). Should treatment effects be estimated in pilot and feasibility studies?. Pilot and Feasibility Studies, 5, Article 107. https://doi.org/10.1186/s40814-019-0493-7

Background Feasibility studies and external pilot studies are used increasingly to inform planning decisions related to a definitive randomized controlled trial. These studies can provide information on process measures, such as consent rates, treat... Read More about Should treatment effects be estimated in pilot and feasibility studies?.

Focus group methodology: some ethical challenges (2019)
Journal Article
Sim, J., & Waterfield, J. (2019). Focus group methodology: some ethical challenges. Quality and Quantity, 53, 3003–3022. https://doi.org/10.1007/s11135-019-00914-5

Focus group methodology generates distinct ethical challenges that do not correspond fully to those raised by one-to-one interviews. This paper explores, in both conceptual and practical terms, three key issues: consent; confdentiality and anonymity;... Read More about Focus group methodology: some ethical challenges.

Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy (2019)
Journal Article
Sim. (2019). Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy. Theoretical Medicine and Bioethics, 40, 83 -101. https://doi.org/10.1007/s11017-019-09481-0

Outcome-adaptive randomization (OAR) has been proposed as a corrective to certain ethical difficulties inherent in the traditional randomized clinical trial (RCT) using fixed-ratio randomization. In particular, it has been suggested that OAR redresse... Read More about Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy.

Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy (2019)
Journal Article
Sim. (2019). Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy. Theoretical Medicine and Bioethics, 83-101. https://doi.org/10.1007/s11017-019-09481-0

Outcome-adaptive randomization (OAR) has been proposed as a corrective to certain ethical difficulties inherent in the traditional randomized clinical trial (RCT) using fixed-ratio randomization. In particular, it has been suggested that OAR redresse... Read More about Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy.