All Outputs (6)

The Developing Landscape of Diagnostic and Prognostic Biomarkers for Spinal Cord Injury in Cerebrospinal Fluid and Blood (2016)
Journal Article
Hulme, C., Brown, S., Fuller, H., Riddell, J., Osman, A., Chowdhury, J., …Wright, K. (2017). The Developing Landscape of Diagnostic and Prognostic Biomarkers for Spinal Cord Injury in Cerebrospinal Fluid and Blood. Spinal Cord, 55, 114-125. https://doi.org/10.1038/sc.2016.174

Objectives: The identification of prognostic biomarkers of spinal cord injury (SCI) will help to assign SCI patients to the correct treatment and rehabilitation regimes. Further, the detection of biomarkers that predict permanent neurological outcom... Read More about The Developing Landscape of Diagnostic and Prognostic Biomarkers for Spinal Cord Injury in Cerebrospinal Fluid and Blood.

Analysis of cartilage oligomeric matrix protein in synovial fluid, plasma and repair tissue of patients treated with autologous chondrocyte implantation (2016)
Journal Article
McCarthy, H., Wright, K., Williams, J., Gallacher, P., Richardson, J., & Roberts, S. (2016). Analysis of cartilage oligomeric matrix protein in synovial fluid, plasma and repair tissue of patients treated with autologous chondrocyte implantation. International Journal of Experimental Pathology, A11 -A12. https://doi.org/10.1111/iep.12211

Meeting abstract.

Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat. (2016)
Journal Article
Garcia, J., Mennan, C., McCarthy, H. S., Roberts, S., Richardson, J. B., & Wright, K. T. (2016). Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat. Stem Cells International, 2016, Article 6969726. https://doi.org/10.1155/2016/6969726

Autologous chondrocyte implantation (ACI) is a cell-based therapy that has been used clinically for over 20 years to treat cartilage injuries more efficiently in order to negate or delay the need for joint replacement surgery. In this time, very litt... Read More about Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat..

Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus. (2016)
Journal Article
Garcia, J., Wright, K., Roberts, S., Herman Kuiper, J., Mangham, C., Richardson, J., & Mennan, C. (2016). Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus. Scientific reports, 6, 24295 -?. https://doi.org/10.1038/srep24295

The infrapatellar fat pad (FP) and synovial fluid (SF) in the knee serve as reservoirs of mesenchymal stromal cells (MSCs) with potential therapeutic benefit. We determined the influence of the donor on the phenotype of donor matched FP and SF derive... Read More about Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus..

Obesity does not affect the size of infrapatellar fat pad adipocytes: implications for the pathogenesis of knee osteoarthritis (2016)
Journal Article
Garcia, J., Wei, W., Runhaar, J., Wright, K., Mennan, C., Roberts, S., …Bastiaansen-Jenniskens, Y. (2016). Obesity does not affect the size of infrapatellar fat pad adipocytes: implications for the pathogenesis of knee osteoarthritis. Osteoarthritis and Cartilage, 24(S1), S334-S335. https://doi.org/10.1016/j.joca.2016.01.599

Purpose: Obesity is known to be a risk factor for the development of osteoarthritis (OA). Obesity is accompanied by adipocyte hypertrophy and elevated inflammation in subcutaneous and visceral adipose tissue. The infrapatellar fat pad (IPFP) is an ad... Read More about Obesity does not affect the size of infrapatellar fat pad adipocytes: implications for the pathogenesis of knee osteoarthritis.

Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation (2016)
Journal Article
Wright, K., & Roberts, S. (2016). Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation. Stem Cells International, 5415901 - ?

Much emphasis has been placed recently on the repair of degenerate discs using implanted cells, such as disc cells or bone marrow derived mesenchymal stem cells (MSCs). This study examines the temporal response of bovine and human nucleus pulposus (N... Read More about Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation.