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All Outputs (179)

Development of a core capability framework for qualified health professionals to optimise care for people with osteoarthritis: an OARSI initiative (2019)
Journal Article
Hinman, R., Allen, K., Bennell, K., Berenbaum, F., Betteridge, N., Briggs, A., …van der Esch, M. (2020). Development of a core capability framework for qualified health professionals to optimise care for people with osteoarthritis: an OARSI initiative. Osteoarthritis and Cartilage, 28(2), 154-166. https://doi.org/10.1016/j.joca.2019.12.001

Summary Objective Develop a generic trans-disciplinary, skills-based capability framework for health professionals providing care for people with OA. Design e-Delphi survey. An international inter-professional Delphi Panel (researchers; clinicians; c... Read More about Development of a core capability framework for qualified health professionals to optimise care for people with osteoarthritis: an OARSI initiative.

The Osteoarthritis Thumb Therapy (OTTER) II Trial: a study protocol for a three-arm multi-centre randomised placebo controlled trial of the clinical effectiveness and efficacy and cost-effectiveness of splints for symptomatic thumb base osteoarthritis (2019)
Journal Article
Dziedzic. (2019). The Osteoarthritis Thumb Therapy (OTTER) II Trial: a study protocol for a three-arm multi-centre randomised placebo controlled trial of the clinical effectiveness and efficacy and cost-effectiveness of splints for symptomatic thumb base osteoarthritis. BMJ Open, e028342 - ?. https://doi.org/10.1136/bmjopen-2018-028342

INTRODUCTION The economic cost of osteoarthritis (OA) is high. At least 4.4?million people have hand OA in the UK. Symptomatic thumb base OA affects 20% of people over 55 years, causing more pain, work and functional disability than OA elsewhere in... Read More about The Osteoarthritis Thumb Therapy (OTTER) II Trial: a study protocol for a three-arm multi-centre randomised placebo controlled trial of the clinical effectiveness and efficacy and cost-effectiveness of splints for symptomatic thumb base osteoarthritis.

Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia (2019)
Journal Article
Jayaweera, K., M Craig, J., M S Zavos, H., Abeysinghe, N., De Alwis, S., Andras, A., …Sumathipala, A. (2019). Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia. BMJ Open, 9(10), Article e029332. https://doi.org/10.1136/bmjopen-2019-029332

INTRODUCTION: Worldwide, 10%-20% of children and adolescents experience mental health conditions. However, most such disorders remain undiagnosed until adolescence or adulthood. Little is known about the factors that influence mental health in childr... Read More about Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia.

Implementing a structured model for osteoarthritis care in primary healthcare: A stepped-wedge cluster-randomised trial (2019)
Journal Article
Dziedzic. (2019). Implementing a structured model for osteoarthritis care in primary healthcare: A stepped-wedge cluster-randomised trial. PLoS Medicine, 1 - 19. https://doi.org/10.1371/journal.pmed.1002949

Author summary Why was this study done? Hip and knee osteoarthritis is a common chronic joint disease in the adult population causing significant pain and disability. Non-surgical treatment modalities including patient osteoarthritis education, exerc... Read More about Implementing a structured model for osteoarthritis care in primary healthcare: A stepped-wedge cluster-randomised trial.

Predictors of pain interference and potential gain from intervention in community dwelling adults with joint pain: A prospective cohort study. (2019)
Journal Article
Blagojevic-Bucknall, M., Thomas, M. J., Wulff, J., Porcheret, M., Dziedzic, K. S., Peat, G. M., …Van Der Windt, D. A. (2019). Predictors of pain interference and potential gain from intervention in community dwelling adults with joint pain: A prospective cohort study. Musculoskeletal Care, 231-240. https://doi.org/10.1002/msc.1406

INTRODUCTION: There is little research on identifying modifiable risk factors that predict future interference of pain with daily activity in people with joint pain, and the estimation of the corresponding population attributable risk (PAR). The pres... Read More about Predictors of pain interference and potential gain from intervention in community dwelling adults with joint pain: A prospective cohort study..

Response to: Losina E. Why past research successes do not translate to clinical reality: gaps in evidence on exercise program efficiency. Osteoarthritis and Cartilage 2019;27:1-2 (2019)
Journal Article
Swaithes, L., Dziedzic, K., Cottrell, E., & Quicke, J. (2019). Response to: Losina E. Why past research successes do not translate to clinical reality: gaps in evidence on exercise program efficiency. Osteoarthritis and Cartilage 2019;27:1-2. Osteoarthritis and Cartilage, e7-e8. https://doi.org/10.1016/j.joca.2019.02.801

Letter to the editor.

Predictors of pain interference and potential gain from intervention in community dwelling adults with joint pain: A prospective cohort study (2019)
Journal Article
Blagojevic-Bucknall, M., Thomas, M. J., Wulff, J., Porcheret, M., Dziedzic, K. S., Peat, G. M., …van der Windt, D. A. (2019). Predictors of pain interference and potential gain from intervention in community dwelling adults with joint pain: A prospective cohort study. Musculoskeletal Care, 17(3), 231-240. https://doi.org/10.1002/msc.1406

Priorities for the effective implementation of osteoarthritis management programs: an OARSI international consensus exercise (2019)
Journal Article
Eyles, J. P., Hunter, D. J., Bennell, K. L., Dziedzic, K. S., Hinman, R. S., van der Esch, M., …Jinks, C. (2019). Priorities for the effective implementation of osteoarthritis management programs: an OARSI international consensus exercise. Osteoarthritis and Cartilage, 27(9), 1270-1279. https://doi.org/10.1016/j.joca.2019.05.015

Objective The Joint Effort Initiative was endorsed by Osteoarthritis Research Society International (OARSI) in 2018 as a collaboration between international researchers and clinicians with an interest in the implementation of osteoarthritis manageme... Read More about Priorities for the effective implementation of osteoarthritis management programs: an OARSI international consensus exercise.

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. (2018)
Journal Article
Chesterton, L. S., Blagojevic-Bucknall, M., Burton, C., Dziedzic, K. S., Davenport, G., Jowett, S. M., …Roddy, E. (2018). The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. The Lancet, 392(10156), 1423 - 1433. https://doi.org/10.1016/s0140-6736%2818%2931572-1

Background To our knowledge, the comparative effectiveness of commonly used conservative treatments for carpal tunnel syndrome has not been evaluated previously in primary care. We aimed to compare the clinical and cost-effectiveness of night splint... Read More about The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial..

Identification and Evaluation of Self-Report Physical Activity Instruments in Adults With Osteoarthritis: A Systematic Review (2018)
Journal Article
Dziedzic, K., Holden, M., & Healey, E. L. (2019). Identification and Evaluation of Self-Report Physical Activity Instruments in Adults With Osteoarthritis: A Systematic Review. Arthritis Care and Research, 71(2), 237-251. https://doi.org/10.1002/acr.23787

OBJECTIVE To identify and evaluate the measurement properties of self-report physical activity (PA) instruments suitable for those with osteoarthritis (OA). METHODS A comprehensive two-stage systematic review using multiple electronic databases... Read More about Identification and Evaluation of Self-Report Physical Activity Instruments in Adults With Osteoarthritis: A Systematic Review.

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management (2018)
Journal Article
Marshall, M., Watt, F. E., Vincent, T. L., & Dziedzic, K. (2018). Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management. Nature Reviews Rheumatology, 14, 641-656. https://doi.org/10.1038/s41584-018-0095-4

Osteoarthritis (OA) is a highly prevalent condition and the hand is the most commonly affected site. Patients with hand OA frequently report symptoms of pain, functional limitations, and frustration in undertaking everyday activities. The condition p... Read More about Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management.

Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain (2018)
Journal Article
Healey, E. L., Afolabi, E. K., Lewis, M., Edwards, J. J., Jordan, K. P., Finney, A., …Dziedzic, K. S. (2018). Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain. BMC Musculoskeletal Disorders, 19, Article 295. https://doi.org/10.1186/s12891-018-2196-2

Background Osteoarthritis (OA) is a leading cause of pain and disability. NICE OA guidelines (2008) recommend that patients with OA should be offered core treatments in primary care. Assessments of OA management have identified a need to improve pri... Read More about Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain.

Relationship of anxiety with joint pain and its management: A population survey (2018)
Journal Article
Barnett, L. A., Pritchard, M. G., Edwards, J. J., Afolabi, E. K., Jordan, K. P., Healey, E. L., …Dziedzic, K. S. (2018). Relationship of anxiety with joint pain and its management: A population survey. Musculoskeletal Care, 16(3), 353-362. https://doi.org/10.1002/msc.1243

Objectives The aims of the present study was to examine the associations between the severity of pain and anxiety in a community population reporting joint pain, and to investigate the management of joint pain in the presence of comorbid anxiety.... Read More about Relationship of anxiety with joint pain and its management: A population survey.

Challenges and controversies of complex interventions in osteoarthritis management: recognizing inappropriate and discordant care (2018)
Journal Article
Dziedzic, K. S., & Allen, K. D. (2018). Challenges and controversies of complex interventions in osteoarthritis management: recognizing inappropriate and discordant care. Rheumatology, 57(S4), 88 - 98. https://doi.org/10.1093/rheumatology/key062

A number of controversies and challenges exist for the management of OA in health care. This paper describes the challenges and gaps in OA care, particularly in relation to population health management, complex interventions and outcomes. It sets thi... Read More about Challenges and controversies of complex interventions in osteoarthritis management: recognizing inappropriate and discordant care.

Implementing international osteoarthritis guidelines in an integrated care model – results from a cluster randomized controlled trial (2018)
Journal Article
Østerås, N., Moseng, T., van Bodegom-Vos, L., Dziedzic, K., Mdala, I., Natvig, B., …Hagen, K. (2018). Implementing international osteoarthritis guidelines in an integrated care model – results from a cluster randomized controlled trial. Osteoarthritis and Cartilage, 26(S1), https://doi.org/10.1016/j.joca.2018.02.085

Purpose: Previous research indicates that people with osteoarthritis (OA) are not receiving the recommended and optimal treatment. Based on international treatment recommendations for hip and knee OA and previous research, the SAMBA model for integra... Read More about Implementing international osteoarthritis guidelines in an integrated care model – results from a cluster randomized controlled trial.

Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial (2018)
Journal Article
Dziedzic. (2018). Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial. Annals of Internal Medicine, https://doi.org/10.7326/M17-1430

Background: Synovitis is believed to play a role in producing symptoms in persons with hand osteoarthritis, but data on slow-acting anti-inflammatory treatments are sparse. Objective: To determine the effectiveness of hydroxychloroquine versus placeb... Read More about Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial.

Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis (2018)
Journal Article
Oppong, R., Jowett, S., Lewis, M., Clarkson, K., Paskins, Z., Croft, P., …Dziedzic, K. (2018). Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis. Rheumatology, 57(6), 1056-1063. https://doi.org/10.1093/rheumatology/key037

Objectives: The aim of this study was to estimate the cost-effectiveness of a model OA consultation for OA to support self-management compared with usual care. Methods: An incremental cost-utility analysis using patient responses to the three-level E... Read More about Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis.

Evidence flowers: An innovative, visual method of presenting “best evidence” summaries to health professional and lay audiences (2018)
Journal Article
Babatunde, O., Tan, V., Jordan, J., Dziedzic, K., Chew-Graham, C., Jinks, C., …Van Der Windt, D. (2018). Evidence flowers: An innovative, visual method of presenting “best evidence” summaries to health professional and lay audiences. Research Synthesis Methods, 9(2), 273-284. https://doi.org/10.1002/jrsm.1295

Background & Aims Barriers to dissemination and engagement with evidence pose a threat to implementing evidence-based medicine. Understanding, retention, and recall can be enhanced by visual presentation of information. The aim of this exploratory r... Read More about Evidence flowers: An innovative, visual method of presenting “best evidence” summaries to health professional and lay audiences.

Enhancing delivery of osteoarthritis care in the general practice consultation: evaluation of a behaviour change intervention (2018)
Journal Article
Porcheret, M., Main, C., Croft, P., & Dziedzic, K. (2018). Enhancing delivery of osteoarthritis care in the general practice consultation: evaluation of a behaviour change intervention. BMC Family Practice, 19, Article 26. https://doi.org/10.1186/s12875-018-0715-8

BACKGROUND: Professionally-focussed behaviour change intervention (BCI) workshops were utilised in the Management of OsteoArthritis in Consultations (MOSAICS) trial investigating the feasibility of implementing the National Institute for Health and C... Read More about Enhancing delivery of osteoarthritis care in the general practice consultation: evaluation of a behaviour change intervention.