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Temporal Trends and Factors Associated With the Inclusion of Patient-Reported Outcomes in Heart Failure Randomized Controlled Trials: A Systematic Review. (2021)
Journal Article
Eliya, Y., Averbuch, T., Le, N., Xie, F., Thabane, L., Mamas, M. A., & Van Spall, H. G. (2021). Temporal Trends and Factors Associated With the Inclusion of Patient-Reported Outcomes in Heart Failure Randomized Controlled Trials: A Systematic Review. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, e022353 - ?. https://doi.org/10.1161/JAHA.121.022353

Background Patient-reported outcomes (PROs) are important measures of treatment response in heart failure. We assessed temporal trends in and factors associated with inclusion of PROs in heart failure randomized controlled trials (RCTs). Methods and... Read More about Temporal Trends and Factors Associated With the Inclusion of Patient-Reported Outcomes in Heart Failure Randomized Controlled Trials: A Systematic Review..

Impact of malignancy on In-hospital mortality, stratified by the cause of admission: An analysis of 67 million patients from the National Inpatient Sample. (2021)
Journal Article
Mamas. (2021). Impact of malignancy on In-hospital mortality, stratified by the cause of admission: An analysis of 67 million patients from the National Inpatient Sample. International Journal of Clinical Practice, e14758 - ?. https://doi.org/10.1111/ijcp.14758

OBJECTIVE: To describe the patient characteristics and the reason for admission of patients with malignancy by malignancy, and to study mortality rates for the different causes of admissions among the different types of cancer. PATIENTS AND METHODS:... Read More about Impact of malignancy on In-hospital mortality, stratified by the cause of admission: An analysis of 67 million patients from the National Inpatient Sample..

Outcomes of rotational atherectomy versus orbital atherectomy for the treatment of heavily calcified coronary stenosis: A systematic review and meta-analysis. (2021)
Journal Article
Mamas. (2021). Outcomes of rotational atherectomy versus orbital atherectomy for the treatment of heavily calcified coronary stenosis: A systematic review and meta-analysis. Catheterization and Cardiovascular Interventions, 884 - 892. https://doi.org/10.1002/ccd.29430

INTRODUCTION: The optimal approach to deal with severe coronary artery calcification (CAC) during percutaneous coronary intervention (PCI) remains ill-defined. METHODS: We conducted an electronic database search of all published studies comparing Orb... Read More about Outcomes of rotational atherectomy versus orbital atherectomy for the treatment of heavily calcified coronary stenosis: A systematic review and meta-analysis..

Trends in cardiovascular mortality of cancer patients in the US over two decades 1999-2019. (2021)
Journal Article
Mamas, M. (2021). Trends in cardiovascular mortality of cancer patients in the US over two decades 1999-2019. International Journal of Clinical Practice, e14841 - ?. https://doi.org/10.1111/ijcp.14841

BACKGROUND: Cancer is the second most common cause of death globally after cardiovascular disease, and cancer patients are at an increased risk of CV death. This recognition has led to publication of cardio-oncological guidelines and to the widesprea... Read More about Trends in cardiovascular mortality of cancer patients in the US over two decades 1999-2019..

Relation of High-Sensitivity Troponin to 1 Year Mortality in 20,000 Consecutive Hospital Patients Undergoing a Blood Test for Any Reason. (2021)
Journal Article
Hinton, J., Mariathas, M., Gabara, L., Allan, R., Nicholas, Z., Shing Kwok, C., …Curzen, N. (2021). Relation of High-Sensitivity Troponin to 1 Year Mortality in 20,000 Consecutive Hospital Patients Undergoing a Blood Test for Any Reason. American Journal of Cardiology, 124 - 131. https://doi.org/10.1016/j.amjcard.2021.07.050

This was an observational study of the 1-year outcomes of the 20,000 patients included in the original CHARIOT study. The aim of the study was to assess the association between high sensitivity troponin I (hs-cTnI) concentration and 1 year mortality... Read More about Relation of High-Sensitivity Troponin to 1 Year Mortality in 20,000 Consecutive Hospital Patients Undergoing a Blood Test for Any Reason..

Shock index predicts up to 90-day mortality risk after intracerebral haemorrhage. (2021)
Journal Article
Pana, T. A., Quinn, T. J., Perdomo-Lampignano, J. A., Szlachetka, W. A., Knoery, C., Mamas, M. A., …Collaborators, V. (2021). Shock index predicts up to 90-day mortality risk after intracerebral haemorrhage. Clinical Neurology and Neurosurgery, 106994 - ?. https://doi.org/10.1016/j.clineuro.2021.106994

BACKGROUND: Shock index (SI - heart rate/systolic blood pressure) has been studied as a measure of haemodynamic status. We aimed to determine whether SI measures within 72 h of admission were associated with adverse outcomes in intracerebral haemorrh... Read More about Shock index predicts up to 90-day mortality risk after intracerebral haemorrhage..

Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic (2021)
Journal Article
Shoaib, A., Van Spall, H. G. C., Wu, J., Cleland, J. G. F., McDonagh, T. A., Rashid, M., …Mamas, M. A. (2021). Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic. European Heart Journal - Quality of Care and Clinical Outcomes, 7(4), 378-387. https://doi.org/10.1093/ehjqcco/qcab040

Aims We hypothesized that a decline in admissions with heart failure during COVID-19 pandemic would lead to a reciprocal rise in mortality for patients with heart failure in the community. Methods and results We used National Heart Failure Audit d... Read More about Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic.

Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk. (2021)
Journal Article
Mamas, M. (2021). Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk. https://doi.org/10.1056/NEJMoa2108749

BACKGROUND: The appropriate duration of dual antiplatelet therapy in patients at high risk for bleeding after the implantation of a drug-eluting coronary stent remains unclear. METHODS: One month after they had undergone implantation of a biodegradab... Read More about Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk..

Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest. (2021)
Journal Article
Mamas, M., & Rashid, M. (2021). Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest. Resuscitation, 327-334. https://doi.org/10.1016/j.resuscitation.2021.10.031

OBJECTIVES: We aimed to identify whether the availability of catheter laboratory affects clinical outcomes of out-of-hospital cardiac arrest (OHCA) complicating myocardial infarction (AMI). METHODS: Patients admitted with a diagnosis of AMI and OHCA... Read More about Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest..

Outcomes of intravascular ultrasound versus optical coherence tomography guided percutaneous coronary angiography: A meta regression-based analysis. (2021)
Journal Article
Mamas, M. A., Sattar, Y., Abdul Razzack, A., Kompella, R., Alhajri, N., Arshad, J., …Alraies, M. C. (2022). Outcomes of intravascular ultrasound versus optical coherence tomography guided percutaneous coronary angiography: A meta regression-based analysis. Catheterization and Cardiovascular Interventions, 99(1), E1 - E11. https://doi.org/10.1002/ccd.29976

BACKGROUND: Studies comparing clinical outcomes with intravascular ultrasound (IVUS) versus optical coherence tomography (OCT) guidance for percutaneous coronary intervention (PCI) in patients presenting with coronary artery disease, including stable... Read More about Outcomes of intravascular ultrasound versus optical coherence tomography guided percutaneous coronary angiography: A meta regression-based analysis..

Meta-Analysis of Transradial Versus Transfemoral Access for Percutaneous Coronary Intervention in Patients With Chronic Kidney Disease. (2021)
Journal Article
Mamas. (2021). Meta-Analysis of Transradial Versus Transfemoral Access for Percutaneous Coronary Intervention in Patients With Chronic Kidney Disease. American Journal of Cardiology, 8 - 14. https://doi.org/10.1016/j.amjcard.2021.07.018

Data comparing outcomes of transradial (TR) versus transfemoral (TF) access for percutaneous coronary intervention (PCI) in chronic kidney disease (CKD) including patients with eGFR< 30 ml/min/1.73m2 and patients with end-stage renal disease on dialy... Read More about Meta-Analysis of Transradial Versus Transfemoral Access for Percutaneous Coronary Intervention in Patients With Chronic Kidney Disease..

Impact of cancer diagnosis on causes and outcomes of 5.9 million US patients with cardiovascular admissions. (2021)
Journal Article
Mamas. (2021). Impact of cancer diagnosis on causes and outcomes of 5.9 million US patients with cardiovascular admissions. International Journal of Cardiology, 76 - 83. https://doi.org/10.1016/j.ijcard.2021.07.054

INTRODUCTION: There are limited data on causes of cardiovascular (CV) admissions and associated outcomes among patients with different cancers. METHODS: All CV admissions from the US National Inpatient Sample between October 2015 to December 2017 wer... Read More about Impact of cancer diagnosis on causes and outcomes of 5.9 million US patients with cardiovascular admissions..

Association of quality indicators for acute myocardial infarction and mortality: feasibility and validation study using linked nationwide registry data (2021)
Journal Article
Mamas, & Rashid. (2021). Association of quality indicators for acute myocardial infarction and mortality: feasibility and validation study using linked nationwide registry data. European Heart Journal, https://doi.org/10.1093/eurheartj/ehab724.1328

Abstract Background Quality indicators (QIs) have been increasingly used as tools to assess and improve the quality of care for acute myocardial infarction (AMI). However, it is not known if it is feasible to use the 2020 iteration of international A... Read More about Association of quality indicators for acute myocardial infarction and mortality: feasibility and validation study using linked nationwide registry data.

Comparison of risk factors for coronary event in people with unattributed and non-coronary chest pain: an electronic health record cohort study (2021)
Journal Article
Rathod-Mistry, T., Mamas, M., Bailey, J., Chen, Y., Clarson, L., Denaxas, S., …Jordan, K. (2021). Comparison of risk factors for coronary event in people with unattributed and non-coronary chest pain: an electronic health record cohort study. European Heart Journal, 42(S1), https://doi.org/10.1093/eurheartj/ehab724.1350

Background Patients presenting to primary care with chest pain are often not given a cause. Patients with such unattributed chest pain have an increased risk of future cardiovascular disease (CVD) compared to patients with diagnosed non-coronary che... Read More about Comparison of risk factors for coronary event in people with unattributed and non-coronary chest pain: an electronic health record cohort study.

Incidence and one year outcome of periprocedural myocardial infarction following cardiac surgery: are the universal definition and SCAI criteria fit for purpose? (2021)
Journal Article
Hinton, J., Augustine, M., Gabara, L., Mariathas, M., Allan, R., Borca, F., …Curzen, N. (2021). Incidence and one year outcome of periprocedural myocardial infarction following cardiac surgery: are the universal definition and SCAI criteria fit for purpose?. European Heart Journal, 42(Supplement_1), https://doi.org/10.1093/eurheartj/ehab724.1442

Introduction The diagnosis and clinical implication of periprocedural myocardial infarction (PPMI) following coronary artery bypass grafting (CABG) is contentious, especially given its importance in the interpretation of trial data. Two accepted def... Read More about Incidence and one year outcome of periprocedural myocardial infarction following cardiac surgery: are the universal definition and SCAI criteria fit for purpose?.

Temporal trends in the inclusion of patient-reported outcomes in heart failure randomized trials published in high-impact medical journals: a systematic bibliometric review (2021)
Journal Article
Eliya, Y., Averbuch, T., Le, N., Xie, F., Thabane, L., Mamas, M., & Van Spall, H. (2021). Temporal trends in the inclusion of patient-reported outcomes in heart failure randomized trials published in high-impact medical journals: a systematic bibliometric review. European Heart Journal, https://doi.org/10.1093/eurheartj/ehab724.3171

Background Patient reported outcomes (PROs) are important measures of health, particularly in symptomatic conditions such as heart failure (HF), and regulatory agencies have encouraged their collection in randomized controlled trials (RCTs). Purpose... Read More about Temporal trends in the inclusion of patient-reported outcomes in heart failure randomized trials published in high-impact medical journals: a systematic bibliometric review.

The relationship between high-sensitivity troponin taken on admission to critical care, regardless of whether there was a clinical indication for testing, and one year mortality (2021)
Journal Article
Hinton, J., Augustine, M., Gabara, L., Mariathas, M., Allan, R., Borca, F., …Curzen, N. (2021). The relationship between high-sensitivity troponin taken on admission to critical care, regardless of whether there was a clinical indication for testing, and one year mortality. European Heart Journal, 42(Supplement_1), https://doi.org/10.1093/eurheartj/ehab724.1381

Introduction High-sensitivity troponin (hs-cTn) assays now form a key component of the diagnostic pathways for patients presenting to emergency medical services with chest pain. However, hs-cTn concentrations above the manufacturer-provided upper li... Read More about The relationship between high-sensitivity troponin taken on admission to critical care, regardless of whether there was a clinical indication for testing, and one year mortality.

The association between socioeconomic status, sex, race/ethnicity and in-hospital mortality among patients hospitalized for heart failure (2021)
Journal Article
Mamas. (2021). The association between socioeconomic status, sex, race/ethnicity and in-hospital mortality among patients hospitalized for heart failure. Journal of Cardiac Failure, https://doi.org/10.1016/j.cardfail.2021.09.012

Background The association between socioeconomic status (SES), sex, race/ethnicity and outcomes during hospitalization for heart failure (HF) has not previously been investigated. Methods We analyzed HF hospitalizations in the United States National... Read More about The association between socioeconomic status, sex, race/ethnicity and in-hospital mortality among patients hospitalized for heart failure.

Clinical Characteristics, Management Strategies, and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Patients With and Without Prior Coronary Artery Bypass Grafting. (2021)
Journal Article
Mamas, M., & Rashid, M. (2021). Clinical Characteristics, Management Strategies, and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Patients With and Without Prior Coronary Artery Bypass Grafting. https://doi.org/10.1161/JAHA.120.018823

Background There are limited data on the management strategies, temporal trends and clinical outcomes of patients who present with non-ST-segment-elevation myocardial infarction and have a prior history of CABG. Methods and Results We identified 287 ... Read More about Clinical Characteristics, Management Strategies, and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Patients With and Without Prior Coronary Artery Bypass Grafting..