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Rotational atherectomy and same day discharge: safety and growth from a national perspective (2020)
Journal Article
Mamas, & Rashid. (2020). Rotational atherectomy and same day discharge: safety and growth from a national perspective. Catheterization and Cardiovascular Interventions, https://doi.org/10.1002/ccd.29228

Objectives We explore whether same day discharge (SDD) is a feasible and safe practice following rotational atherectomy (ROTA) treatment during elective percutaneous coronary intervention (PCI), and examine which baseline characteristics are indepen... Read More about Rotational atherectomy and same day discharge: safety and growth from a national perspective.

Clinical Characteristics and Outcomes of COVID-19 Positive Acute Coronary Syndrome Patients; a multisource Electronic Healthcare Records Study from England (2020)
Journal Article
Mamas, & Rashid. (2020). Clinical Characteristics and Outcomes of COVID-19 Positive Acute Coronary Syndrome Patients; a multisource Electronic Healthcare Records Study from England. MedRxiv, https://doi.org/10.1101/2020.08.20.20175091

Background: Patients with underlying cardiovascular disease and Coronavirus disease 2019 (COVID-19) infection are at increased risk of morbidity and mortality. However, there is limited information on management and outcomes of patients presenting wi... Read More about Clinical Characteristics and Outcomes of COVID-19 Positive Acute Coronary Syndrome Patients; a multisource Electronic Healthcare Records Study from England.

Socioeconomic Status and Differences in the Management and Outcomes of 6.6 Million US patients with Acute Myocardial Infarction (2020)
Journal Article
Mamas. (2020). Socioeconomic Status and Differences in the Management and Outcomes of 6.6 Million US patients with Acute Myocardial Infarction. American Journal of Cardiology, 10-18. https://doi.org/10.1016/j.amjcard.2020.05.025

Little is known about the impact of socioeconomic status (SES) on management strategies and in-hospital clinical outcomes in patients with acute myocardial infarction (AMI) and its subtypes, and whether these trends have changed over time. All AMI ho... Read More about Socioeconomic Status and Differences in the Management and Outcomes of 6.6 Million US patients with Acute Myocardial Infarction.

Place and underlying cause of death during the COVID19 pandemic: retrospective cohort study of 3.5 million deaths in England and Wales, 2014 to 2020 (2020)
Journal Article
Wu, J., Malfam, M., Mamas, M., Rashid, M., Kontopantelis, E., Deanfield, J. E., …Gale, C. P. (2020). Place and underlying cause of death during the COVID19 pandemic: retrospective cohort study of 3.5 million deaths in England and Wales, 2014 to 2020. MedRxiv, https://doi.org/10.1101/2020.08.12.20173302

Background The COVID-19 pandemic has resulted in a high death toll. We aimed to describe the place and cause of death during the COVID-19 pandemic. Methods This national death registry included all adult (aged =18 years) deaths in England and Wales b... Read More about Place and underlying cause of death during the COVID19 pandemic: retrospective cohort study of 3.5 million deaths in England and Wales, 2014 to 2020.

Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Severe Aortic Stenosis in England (2020)
Journal Article
Mamas, & Nolan. (2020). Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Severe Aortic Stenosis in England. MedRxiv, https://doi.org/10.1101/2020.08.05.20168922

Background Aortic stenosis requires timely treatment with either surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR). This study aimed to investigate the indirect impact of COVID-19 on national SAVR and TAVR acti... Read More about Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Severe Aortic Stenosis in England.

Clinical Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Native Coronary Arteries vs Saphenous Vein Grafts (2020)
Journal Article
Shoaib, A., Johnson, T. W., Banning, A., Ludman, P., Rashid, M., Potts, J., …Mamas, M. A. (2020). Clinical Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Native Coronary Arteries vs Saphenous Vein Grafts. Journal of Invasive Cardiology,

Background. There are limited data comparing outcomes of patients with previous coronary artery bypass grafting (CABG) presenting with stable angina who undergo percutaneous coronary intervention (PCI) to either a saphenous vein grafts (SVG) or a chr... Read More about Clinical Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Native Coronary Arteries vs Saphenous Vein Grafts.

The Predictive Value of CHA2DS2-VASc Score on In-Hospital Death and Adverse Periprocedural Events Among Patients With the Acute Coronary Syndrome and Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention: A 10-Year National Inpatient Sample (NIS) Analysis. (2020)
Journal Article
Borovac, J. A., Shing Kwok, C., Mohamed, M. O., Fischman, D. L., Savage, M., Alraies, C., …Mamas, M. A. (2021). The Predictive Value of CHA2DS2-VASc Score on In-Hospital Death and Adverse Periprocedural Events Among Patients With the Acute Coronary Syndrome and Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention: A 10-Year National Inpatient Sample (NIS) Analysis. Cardiovascular Revascularization Medicine, 29, 61 - 68. https://doi.org/10.1016/j.carrev.2020.08.003

BACKGROUND: The predictive value of CHA2DS2-VASc score regarding the in-hospital death and periprocedural adverse events following percutaneous coronary intervention (PCI) among patients with acute coronary syndrome (ACS) and concomitant atrial fibri... Read More about The Predictive Value of CHA2DS2-VASc Score on In-Hospital Death and Adverse Periprocedural Events Among Patients With the Acute Coronary Syndrome and Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention: A 10-Year National Inpatient Sample (NIS) Analysis..

Safety of transradial access compared to transfemoral access with hemostatic devices (vessel plugs and suture devices) after percutaneous coronary interventions: A systematic review and meta-analysis. (2020)
Journal Article
Chugh, Y., Bavishi, C., Mojadidi, M. K., Elgendy, I. Y., Faillace, R. T., Brilakis, E. S., …Kumar Chugh, S. (2020). Safety of transradial access compared to transfemoral access with hemostatic devices (vessel plugs and suture devices) after percutaneous coronary interventions: A systematic review and meta-analysis. https://doi.org/10.1002/ccd.29061

OBJECTIVES: Comparing the safety of transradial access (TRA) and conventional hemostasis with transfemoral access (TFA) and vascular closure devices (vessel plugs and suture devices) in patients undergoing percutaneous coronary interventions. BACKGRO... Read More about Safety of transradial access compared to transfemoral access with hemostatic devices (vessel plugs and suture devices) after percutaneous coronary interventions: A systematic review and meta-analysis..

Patient response, treatments and mortality for acute myocardial infarction during the COVID-19 pandemic. (2020)
Journal Article
Rashid, & Mamas. (2020). Patient response, treatments and mortality for acute myocardial infarction during the COVID-19 pandemic. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcaa062

AIM: COVID-19 might have affected the care and outcomes of hospitalised acute myocardial infarction (AMI). We aimed to determine whether the COVID-19 pandemic changed patient response, hospital treatment and mortality from AMI. METHODS AND RESULTS: A... Read More about Patient response, treatments and mortality for acute myocardial infarction during the COVID-19 pandemic..

Adoption of same day discharge following elective left main stem percutaneous coronary intervention. (2020)
Journal Article
Mamas, & Rashid. (2020). Adoption of same day discharge following elective left main stem percutaneous coronary intervention. International Journal of Cardiology, https://doi.org/10.1016/j.ijcard.2020.07.038

BACKGROUND: This study sought to investigate the safety and feasibility of same day discharge (SDD) practice and compare clinical outcomes to patients admitted for overnight stay (ON) undergoing elective left main stem (LMS) percutaneous coronary int... Read More about Adoption of same day discharge following elective left main stem percutaneous coronary intervention..

Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy (2020)
Journal Article
Wu, P., Jordan, K. P., Chew‐Graham, C. A., Coutinho, T., Lundberg, G. P., Park, K. E., …Mamas, M. A. (2020). Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 9(15), https://doi.org/10.1161/JAHA.120.016182

Background Stroke is a serious complication of hypertensive disorders of pregnancy (HDP), with potentially severe and long-term sequelae. However, the temporal trends, predictors and outcomes of stroke in women with HDP at delivery remain unknown.... Read More about Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy.

Trends of in-hospital and 30-day mortality after percutaneous coronary intervention in England before and after the COVID-19 era (2020)
Journal Article
Mamas, & Rashid. (2020). Trends of in-hospital and 30-day mortality after percutaneous coronary intervention in England before and after the COVID-19 era. MedRxiv, https://doi.org/10.1101/2020.07.18.20155549v1

Objectives: To examine short-term primary causes of death after percutaneous coronary intervention (PCI) in a national cohort before and during COVID-19. Background: Public reporting of PCI outcomes is a performance metric and a requirement in many h... Read More about Trends of in-hospital and 30-day mortality after percutaneous coronary intervention in England before and after the COVID-19 era.

Percutaneous Intervention or Bypass Graft for Left Main Coronary Artery Disease? A Systematic Review and Meta-Analysis (2020)
Journal Article
Mamas. (2020). Percutaneous Intervention or Bypass Graft for Left Main Coronary Artery Disease? A Systematic Review and Meta-Analysis. Journal of Interventional Cardiology, https://doi.org/10.1155/2020/4081642

Background. The safety and efficacy of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG) for stable left main coronary artery disease (LMCAD) remains controversial.Methods. Digital databases were searched to compa... Read More about Percutaneous Intervention or Bypass Graft for Left Main Coronary Artery Disease? A Systematic Review and Meta-Analysis.

Sex-differences in mortality rates and underlying conditions for COVID-19 deaths in England and Wales (2020)
Journal Article
Mamas, & Rashid. (2020). Sex-differences in mortality rates and underlying conditions for COVID-19 deaths in England and Wales. Mayo Clinic Proceedings, 2110-2124. https://doi.org/10.1016/j.mayocp.2020.07.009

Background: Limited national data exists on the prevalence and distribution of underlying conditions among COVID-19 deaths between sexes and across age groups. Methods: All adult (=18 years) deaths recorded in England and Wales (1st March 2020 to 12t... Read More about Sex-differences in mortality rates and underlying conditions for COVID-19 deaths in England and Wales.

Infective endocarditis is associated with worse outcomes in stroke: A Thailand National Database Study. (2020)
Journal Article
Mamas. (2020). Infective endocarditis is associated with worse outcomes in stroke: A Thailand National Database Study. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.13614

BACKGROUND: There is lack of data on the association between infective endocarditis (IE) and outcomes of mortality and complications is stroke. We aimed to compare characteristics and outcomes of stroke patients with and without IE. METHODS: We retro... Read More about Infective endocarditis is associated with worse outcomes in stroke: A Thailand National Database Study..

26 Distribution of high sensitivity troponin levels in consecutive, unselected patients in the emergency department and relationship to in-hospital mortality (2020)
Journal Article
Hinton, J., Mariathas, M., Gabara, L., Nicholas, Z., Allan, R., Ramamoorthy, S., …Curzen, N. (2020). 26 Distribution of high sensitivity troponin levels in consecutive, unselected patients in the emergency department and relationship to in-hospital mortality. Heart, 106(S2), https://doi.org/10.1136/heartjnl-2020-bcs.26

Introduction The introduction of high-sensitivity troponin assays has facilitated pathways to rapidly exclude myocardial infarction (MI) in patients presenting to the emergency department (ED) with chest pain. However, hs-cTn concentrations above the... Read More about 26 Distribution of high sensitivity troponin levels in consecutive, unselected patients in the emergency department and relationship to in-hospital mortality.

22 Distribution of high sensitivity troponin taken without conventional clinical indications in critical care patients and its association with critical care mortality (2020)
Journal Article
Hinton, J., Augustine, M., Gabara, L., Mariathas, M., Allan, R., Borca, F., …Curzen, N. (2020). 22 Distribution of high sensitivity troponin taken without conventional clinical indications in critical care patients and its association with critical care mortality. Heart, 106(S2), https://doi.org/10.1136/heartjnl-2020-bcs.22

Background High sensitivity troponin (hs-cTn) concentrations above the manufacturer’s upper limit of normal (ULN) are frequently seen outside the context of MI, particularly in critical care patients. The potential value of hs-cTn as a biomarker for... Read More about 22 Distribution of high sensitivity troponin taken without conventional clinical indications in critical care patients and its association with critical care mortality.

Impact of the COVID-19 pandemic on admission rates for, and management of, acute coronary syndromes in England (2020)
Journal Article
Mamas. (2020). Impact of the COVID-19 pandemic on admission rates for, and management of, acute coronary syndromes in England. Lancet, 381-389. https://doi.org/10.1016/S0140-6736%2820%2931356-8

Background Several countries affected by the COVID-19 pandemic have reported a substantial drop in the number of patients attending the emergency department with acute coronary syndromes and a reduced number of cardiac procedures. We aimed to unders... Read More about Impact of the COVID-19 pandemic on admission rates for, and management of, acute coronary syndromes in England.

Multivessel Versus Culprit-Only Revascularization in STEMI and Multivessel Coronary Artery Disease: Meta-Analysis of Randomized Trials. (2020)
Journal Article
Mamas. (2020). Multivessel Versus Culprit-Only Revascularization in STEMI and Multivessel Coronary Artery Disease: Meta-Analysis of Randomized Trials. JACC: Cardiovascular Interventions, 1571 - 1582. https://doi.org/10.1016/j.jcin.2020.04.055

OBJECTIVES: The goal of this systematic review and meta-analysis was to provide a comprehensive evaluation of contemporary randomized trials addressing the efficacy and safety of multivessel versus culprit vessel-only percutaneous coronary interventi... Read More about Multivessel Versus Culprit-Only Revascularization in STEMI and Multivessel Coronary Artery Disease: Meta-Analysis of Randomized Trials..