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Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database (2018)
Journal Article
Mamas. (2018). Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database. JACC. Cardiovascular interventions, 2480-2491. https://doi.org/10.1016/j.jcin.2018.09.035

Objectives Using the British Cardiovascular Intervention Society percutaneous coronary intervention (PCI) database, temporal trends, predictors, and outcomes of radial access (RA) versus femoral access (FA) for unprotected left main stem percutaneou... Read More about Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database.

Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis (2018)
Journal Article
Wong, C., Kwok, C., Narain, A., Gulati, M., Mihalidou, A., Wu, P., …Mamas, M. (2018). Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis. Heart, 1937-1948. https://doi.org/10.1136/heartjnl-2018-313005

Background The influence of marital status on the incidence of cardiovascular disease (CVD) and prognosis after CVD is inconclusive. We systematically reviewed the literature to determine how marital status influences CVD and prognosis after CVD.... Read More about Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis.

Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation (2018)
Journal Article
Mamas. (2018). Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation. Heart, 2058-2066. https://doi.org/10.1136/heartjnl-2018-313356

OBJECTIVES To investigate the association of the CharlsonComorbidity Index (CCI) with clinical outcomes after transcatheter aortic valve implantation (TAVI). BACKGROUND: Patients undergoing TAVI have high comorbid burden; however, there is limite... Read More about Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation.

Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts (2018)
Journal Article
Shoaib, A., Kinnaird, T., Curzen, N., Kontopantelis, E., Ludman, P., de Belder, M., …Mamas, M. (2018). Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts. Circulation: Cardiovascular Interventions, 11(11), https://doi.org/10.1161/circinterventions.118.006824

Background: There are limited data on outcomes of patients with previous CABG presenting with NSTEMI undergoing PCI. We compare clinical characteristics and outcomes in NSTEMI patients undergoing PCI with or without prior CABG surgery in a national c... Read More about Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts.

Pre-Procedural Risk Models for Patients Undergoing Transcatheter Aortic Valve Implantation (2018)
Journal Article
Mamas. (2018). Pre-Procedural Risk Models for Patients Undergoing Transcatheter Aortic Valve Implantation. Journal of thoracic disease, https://doi.org/10.21037/jtd.2018.05.67

Transcatheter aortic valve implantation (TAVI) has emerged as the standard treatment option for patients with symptomatic aortic stenosis who are considered intermediate to high surgical risk. Nonetheless, optimal clinical outcomes following the proc... Read More about Pre-Procedural Risk Models for Patients Undergoing Transcatheter Aortic Valve Implantation.

Incidence and clinical course of limb dysfunction post cardiac catheterization: a systematic review (2018)
Journal Article
Ayyaz Ul Haq, M., Rashid, M., Gilchrist, I. C., Bertrand, O., Shing Kwok, C., Wai Wong, C., …Mamas, M. A. (2018). Incidence and clinical course of limb dysfunction post cardiac catheterization: a systematic review. Circulation Journal, 82(11), 2736. https://doi.org/10.1253/circj.CJ-18-0389

Background We sought to systematically review the available literature on limb dysfunction after transradial or transfemoral cardiac catheterization. Methods & Results MEDLINE and EMBASE were searched for studies evaluating any transradial or... Read More about Incidence and clinical course of limb dysfunction post cardiac catheterization: a systematic review.

Explaining North-South disparities in mortality rates among 25-44 year olds in England: a longitudinal population study (2018)
Journal Article
Mamas. (2018). Explaining North-South disparities in mortality rates among 25-44 year olds in England: a longitudinal population study. The Lancet Public Health, https://doi.org/10.1016/s2468-2667%2818%2930177-4

Background: There has been a marked recent increase in excess mortality for adults aged 25-44 in the North compared to the South of England. We examined the underlying causes of the excess mortality and the relative contribution of socioeconomic depr... Read More about Explaining North-South disparities in mortality rates among 25-44 year olds in England: a longitudinal population study.

Transradial Approach for Left Ventricular Endomyocardial Biopsy (2018)
Journal Article
Mamas. (2018). Transradial Approach for Left Ventricular Endomyocardial Biopsy. Canadian Journal of Cardiology, 1283-1288. https://doi.org/10.1016/j.cjca.2018.05.007

Background Left ventricular endomyocardial biopsy (LV-EMB) may offer a superior diagnostic yield compared with right ventricular endomyocardial biopsy (RV-EMB) in conditions predominantly affecting the LV but is underused compared with RV-EMB. Despi... Read More about Transradial Approach for Left Ventricular Endomyocardial Biopsy.

Association of different antiplatelet therapies with mortality after primary percutaneous coronary intervention (2018)
Journal Article
Mamas, & Rashid. (2018). Association of different antiplatelet therapies with mortality after primary percutaneous coronary intervention. Heart, 1683-1690. https://doi.org/10.1136/heartjnl-2017-312366

Objectives Prasugrel and ticagrelor both reduce ischaemic endpoints in high-risk acute coronary syndromes, compared with clopidogrel. However, comparative outcomes of these two newer drugs in the context of primary percutaneous coronary intervention... Read More about Association of different antiplatelet therapies with mortality after primary percutaneous coronary intervention.

Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society Database (2018)
Journal Article
Mamas. (2018). Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society Database. Catheterization and Cardiovascular Interventions, 659-665. https://doi.org/10.1002/ccd.27493

Objective This study aims to evaluate outcomes associated with different P2Y12 agents in Saphenous Vein graft (SVG) percutaneous coronary intervention (PCI). Background and Methods SVG PCI is associated with greater risks of ischemic complicat... Read More about Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society Database.

Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis (2018)
Journal Article
Mamas. (2018). Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis. JACC. Cardiovascular interventions, 1759-1771. https://doi.org/10.1016/j.jcin.2018.04.042

Objectives: We sought to assess the clinical outcomes of patients undergoing transcatheter aortic valve implantation (TAVI) with early discharge (ED) versus standard discharge (SD) pathways. Background: Minimalist approaches for TAVI have been dev... Read More about Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis.

Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States (2018)
Journal Article
Ensor, J., Burke, D., Kwok, C., Riley, R., Holmvang, L., Mamas, M., …Rashid, M. (2018). Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States. PloS one, https://doi.org/10.1371/journal.pone.0203325

Background Prior studies have reported inconsistencies in the baseline risk profile, comorbidity burden and their association with clinical outcomes in women compared to men. More importantly, there is limited data around the sex differences and how... Read More about Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States.

Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis (2018)
Journal Article
Chew-Graham, & Mamas. (2018). Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/jaha.118.008552

Abstract Background: There is growing evidence that sleep duration and quality may be associated with cardiovascular harm and mortality. Methods and Results: We conducted a systematic review, meta-analysis and spline analysis of prospective cohort st... Read More about Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis.

Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database). (2018)
Journal Article
Kwok, C., Mamas, M., Martinez, S., Pancholy, S., Ahmed, W., Al-Shaibi, K., …Curzen, N. (2018). Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database). Scientific reports, 11156 -?. https://doi.org/10.1038/s41598-018-29303-y

It is unclear how comorbidity influences rates and causes of unplanned readmissions following percutaneous coronary intervention (PCI). We analyzed patients in the Nationwide Readmission Database who were admitted to hospital between 2010 and 2014. T... Read More about Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database)..

Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States (2018)
Journal Article
Al Shaibi, K., Gulati, R., Bell, M., Anderson, V., Potts, J., Rashid, M., …Kwok, C. (2018). Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States. JACC. Cardiovascular interventions, 1354-1364. https://doi.org/10.1016/j.jcin.2018.03.049

Discharge against medical advice (DAMA) in the context of PCI has not been described in the literature. Among the 2,021,104 patients, the proportion of patients who DAMA was 0.5% (n=10,049). Important predictors of DAMA included diagnosis of acute my... Read More about Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States.

Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database) (2018)
Journal Article
Martinez, S., Rao, S., Gilchrist, I., Kwok, C., Al Ayoubi, F., Myint, P., …Kontopantelis, E. (2018). Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database). American Journal of Cardiology, 220-228. https://doi.org/10.1016/j.amjcard.2018.03.367

It is unclear how age affects rates and causes of unplanned early readmissions after per cutaneous coronary intervention (PCI). We analyzed patients in the Nationwide Readmission Database in the United States from 2010 to 2014 and examined the impact... Read More about Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database).

Using electronic health records to quantify and stratify the severity of type 2 diabetes in primary care in England: rationale and cohort study design (2018)
Journal Article
Mamas, Chew-Graham, & Mallen. (2018). Using electronic health records to quantify and stratify the severity of type 2 diabetes in primary care in England: rationale and cohort study design. BMJ Open, https://doi.org/10.1136/bmjopen-2017-020926

Introduction: The increasing prevalence of type 2 diabetes (T2DM) presents a significant burden on affected individuals and health-care systems internationally. There is, however, no agreed validated measure to infer diabetes severity from electronic... Read More about Using electronic health records to quantify and stratify the severity of type 2 diabetes in primary care in England: rationale and cohort study design.

Health economic analysis of access site practice in England during changes in practice: Insights from the British Cardiovascular Interventional Society (2018)
Journal Article
Mamas, M., Tosh, J., Hulme, W., Hoskins, N., Bungey, G., Ludman, P., …Kontopantelis, E. (2018). Health economic analysis of access site practice in England during changes in practice: Insights from the British Cardiovascular Interventional Society. Circulation: Cardiovascular Quality and Outcomes, 11(5), https://doi.org/10.1161/circoutcomes.117.004482

Background: Transradial access (TRA) for percutaneous coronary intervention (PCI) is associated with a reduced risk of mortality compared with transfemoral access, access site–related bleeding complications, and shorter length of stay. The budget imp... Read More about Health economic analysis of access site practice in England during changes in practice: Insights from the British Cardiovascular Interventional Society.

Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology (2018)
Journal Article
Mamas. (2018). Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 853-872. https://doi.org/10.1002/ejhf.1170

The coexistence of type 2 diabetes mellitus (T2DM) and heart failure (HF), either with reduced (HFrEF) or preserved ejection fraction (HFpEF), is frequent (30–40% of patients) and associated with a higher risk of HF hospitalization, all-cause and car... Read More about Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology.

Accelerated patent haemostasis using a procoagulant disk: a protocol designed to minimise the risk of radial artery occlusion following cardiac catheterisation (2018)
Journal Article
Ayyaz Ul Haq, M., Nazir, S. A., Rashid, M., Shing Kwok, C., Mubashiruddin, S., Alisiddiq, Z., …Nolan, J. (2019). Accelerated patent haemostasis using a procoagulant disk: a protocol designed to minimise the risk of radial artery occlusion following cardiac catheterisation. Cardiovascular Revascularization Medicine, 20(2), 137-142. https://doi.org/10.1016/j.carrev.2018.03.026

Purpose Radial artery occlusion flowing cardiac catheterisation has been linked to flow reduction and prolonged compression. We investigate whether these factors can be optimised following transradial cardiac catheterisation by using an accelerated... Read More about Accelerated patent haemostasis using a procoagulant disk: a protocol designed to minimise the risk of radial artery occlusion following cardiac catheterisation.