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Timing and causes of unplanned readmissions after percutaneous coronary intervention: Insights from the Nationwide Readmission Database (2019)
Journal Article
Mamas, M., & Rashid, M. (2019). Timing and causes of unplanned readmissions after percutaneous coronary intervention: Insights from the Nationwide Readmission Database. JACC. Cardiovascular interventions, 734-748. https://doi.org/10.1016/j.jcin.2019.02.007

The rates and causes of readmission at different time periods after PCI remain incompletely elucidated. Among the 2,412,000 patients, 2.5% were readmitted between 0-7 days, 7.6% between 8 and 30 days, 8.9% between 31 and 90 days, and 8.0% between 91... Read More about Timing and causes of unplanned readmissions after percutaneous coronary intervention: Insights from the Nationwide Readmission Database.

Impact of heart failure on stroke mortality and recurrence (2019)
Journal Article
Mamas. (2019). Impact of heart failure on stroke mortality and recurrence. Heart Asia, https://doi.org/10.1136/heartasia-2018-011139

Objective We aimed to examine the impact of heart failure (HF) on stroke mortality (in-hospital and postdischarge) and recurrence in a national stroke cohort from Thailand. Methods We used a large, insurance-based database including all stroke a... Read More about Impact of heart failure on stroke mortality and recurrence.

Radial versus Femoral Approach for Saphenous Vein Grafts Angiography and Interventions (2019)
Journal Article
Mamas. (2019). Radial versus Femoral Approach for Saphenous Vein Grafts Angiography and Interventions. American Heart Journal, 1-8. https://doi.org/10.1016/j.ahj.2018.11.014

Aims Coronary angiography and intervention to saphenous venous grafts (SVGs) remains challenging. This study aimed to investigate the feasibility and safety of the radial approach compared to femoral access in a large cohort of patients undergoing S... Read More about Radial versus Femoral Approach for Saphenous Vein Grafts Angiography and Interventions.

True 99th centile of high sensitivity cardiac troponin for hospital patients: prospective, observational cohort study? (2019)
Journal Article
Mamas. (2019). True 99th centile of high sensitivity cardiac troponin for hospital patients: prospective, observational cohort study?. BMJ, https://doi.org/10.1136/bmj.l729

OBJECTIVE To determine the distribution, and specifically the true 99th centile, of high sensitivity cardiac troponin I (hs-cTnI) for a whole hospital population by applying the hs-cTnI assay currently used routinely at a large teaching hospital.... Read More about True 99th centile of high sensitivity cardiac troponin for hospital patients: prospective, observational cohort study?.

Early readmissions after isolated coronary artery bypass grafting. (2019)
Journal Article
Mamas. (2019). Early readmissions after isolated coronary artery bypass grafting. International Journal of Clinical Practice, e13319 - ?. https://doi.org/10.1111/ijcp.13319

Since its introduction, coronary artery bypass grafting (CABG) has been the revascularisation intervention of choice in patients with complex coronary artery disease [1]. CABG is the most common cardiac surgical procedure [3]. Those reshospitalised w... Read More about Early readmissions after isolated coronary artery bypass grafting..

Discharge Against Medical Advice after Hospitalization for Acute Myocardial Infarction (2019)
Journal Article
Mamas. (2019). Discharge Against Medical Advice after Hospitalization for Acute Myocardial Infarction. Heart, 315-321. https://doi.org/10.1136/heartjnl-2018-313671

Background Discharge against medical advice (AMA) occurs infrequently but is associated with poor outcomes. There are limited descriptions of discharges AMA in national cohorts of patients with acute myocardial infarction (AMI). This study aims to e... Read More about Discharge Against Medical Advice after Hospitalization for Acute Myocardial Infarction.

Relative survival and excess mortality following primary percutaneous coronary intervention for ST-elevation myocardial infarction (2019)
Journal Article
Mamas. (2019). Relative survival and excess mortality following primary percutaneous coronary intervention for ST-elevation myocardial infarction. European Heart Journal: Acute Cardiovascular Care, 68-77. https://doi.org/10.1177/2048872617710790

Background: High survival rates are commonly reported following primary percutaneous coronary intervention for ST-elevation myocardial infarction, with most contemporary studies reporting overall survival. Aims: The aim of this study was to d... Read More about Relative survival and excess mortality following primary percutaneous coronary intervention for ST-elevation myocardial infarction.

Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database (2018)
Journal Article
Mamas. (2018). Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database. JACC. Cardiovascular interventions, 2480-2491. https://doi.org/10.1016/j.jcin.2018.09.035

Objectives Using the British Cardiovascular Intervention Society percutaneous coronary intervention (PCI) database, temporal trends, predictors, and outcomes of radial access (RA) versus femoral access (FA) for unprotected left main stem percutaneou... Read More about Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database.

Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis (2018)
Journal Article
Wong, C., Kwok, C., Narain, A., Gulati, M., Mihalidou, A., Wu, P., …Mamas, M. (2018). Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis. Heart, 1937-1948. https://doi.org/10.1136/heartjnl-2018-313005

Background The influence of marital status on the incidence of cardiovascular disease (CVD) and prognosis after CVD is inconclusive. We systematically reviewed the literature to determine how marital status influences CVD and prognosis after CVD.... Read More about Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis.

Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation (2018)
Journal Article
Mamas. (2018). Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation. Heart, 2058-2066. https://doi.org/10.1136/heartjnl-2018-313356

OBJECTIVES To investigate the association of the CharlsonComorbidity Index (CCI) with clinical outcomes after transcatheter aortic valve implantation (TAVI). BACKGROUND: Patients undergoing TAVI have high comorbid burden; however, there is limite... Read More about Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation.

Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts (2018)
Journal Article
Shoaib, A., Kinnaird, T., Curzen, N., Kontopantelis, E., Ludman, P., de Belder, M., …Mamas, M. (2018). Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts. Circulation: Cardiovascular Interventions, 11(11), https://doi.org/10.1161/circinterventions.118.006824

Background: There are limited data on outcomes of patients with previous CABG presenting with NSTEMI undergoing PCI. We compare clinical characteristics and outcomes in NSTEMI patients undergoing PCI with or without prior CABG surgery in a national c... Read More about Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts.

Pre-Procedural Risk Models for Patients Undergoing Transcatheter Aortic Valve Implantation (2018)
Journal Article
Mamas. (2018). Pre-Procedural Risk Models for Patients Undergoing Transcatheter Aortic Valve Implantation. Journal of thoracic disease, https://doi.org/10.21037/jtd.2018.05.67

Transcatheter aortic valve implantation (TAVI) has emerged as the standard treatment option for patients with symptomatic aortic stenosis who are considered intermediate to high surgical risk. Nonetheless, optimal clinical outcomes following the proc... Read More about Pre-Procedural Risk Models for Patients Undergoing Transcatheter Aortic Valve Implantation.

Incidence and clinical course of limb dysfunction post cardiac catheterization: a systematic review (2018)
Journal Article
Ayyaz Ul Haq, M., Rashid, M., Gilchrist, I. C., Bertrand, O., Shing Kwok, C., Wai Wong, C., …Mamas, M. A. (2018). Incidence and clinical course of limb dysfunction post cardiac catheterization: a systematic review. Circulation Journal, 82(11), 2736. https://doi.org/10.1253/circj.CJ-18-0389

Background We sought to systematically review the available literature on limb dysfunction after transradial or transfemoral cardiac catheterization. Methods & Results MEDLINE and EMBASE were searched for studies evaluating any transradial or... Read More about Incidence and clinical course of limb dysfunction post cardiac catheterization: a systematic review.

Explaining North-South disparities in mortality rates among 25-44 year olds in England: a longitudinal population study (2018)
Journal Article
Mamas. (2018). Explaining North-South disparities in mortality rates among 25-44 year olds in England: a longitudinal population study. The Lancet Public Health, https://doi.org/10.1016/s2468-2667%2818%2930177-4

Background: There has been a marked recent increase in excess mortality for adults aged 25-44 in the North compared to the South of England. We examined the underlying causes of the excess mortality and the relative contribution of socioeconomic depr... Read More about Explaining North-South disparities in mortality rates among 25-44 year olds in England: a longitudinal population study.

Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society Database (2018)
Journal Article
Mamas. (2018). Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society Database. Catheterization and Cardiovascular Interventions, 659-665. https://doi.org/10.1002/ccd.27493

Objective This study aims to evaluate outcomes associated with different P2Y12 agents in Saphenous Vein graft (SVG) percutaneous coronary intervention (PCI). Background and Methods SVG PCI is associated with greater risks of ischemic complicat... Read More about Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society Database.

Transradial Approach for Left Ventricular Endomyocardial Biopsy (2018)
Journal Article
Mamas. (2018). Transradial Approach for Left Ventricular Endomyocardial Biopsy. Canadian Journal of Cardiology, 1283-1288. https://doi.org/10.1016/j.cjca.2018.05.007

Background Left ventricular endomyocardial biopsy (LV-EMB) may offer a superior diagnostic yield compared with right ventricular endomyocardial biopsy (RV-EMB) in conditions predominantly affecting the LV but is underused compared with RV-EMB. Despi... Read More about Transradial Approach for Left Ventricular Endomyocardial Biopsy.

Association of different antiplatelet therapies with mortality after primary percutaneous coronary intervention (2018)
Journal Article
Mamas, & Rashid. (2018). Association of different antiplatelet therapies with mortality after primary percutaneous coronary intervention. Heart, 1683-1690. https://doi.org/10.1136/heartjnl-2017-312366

Objectives Prasugrel and ticagrelor both reduce ischaemic endpoints in high-risk acute coronary syndromes, compared with clopidogrel. However, comparative outcomes of these two newer drugs in the context of primary percutaneous coronary intervention... Read More about Association of different antiplatelet therapies with mortality after primary percutaneous coronary intervention.

Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis (2018)
Journal Article
Mamas. (2018). Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis. JACC. Cardiovascular interventions, 1759-1771. https://doi.org/10.1016/j.jcin.2018.04.042

Objectives: We sought to assess the clinical outcomes of patients undergoing transcatheter aortic valve implantation (TAVI) with early discharge (ED) versus standard discharge (SD) pathways. Background: Minimalist approaches for TAVI have been dev... Read More about Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis.

Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States (2018)
Journal Article
Ensor, J., Burke, D., Kwok, C., Riley, R., Holmvang, L., Mamas, M., …Rashid, M. (2018). Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States. PloS one, https://doi.org/10.1371/journal.pone.0203325

Background Prior studies have reported inconsistencies in the baseline risk profile, comorbidity burden and their association with clinical outcomes in women compared to men. More importantly, there is limited data around the sex differences and how... Read More about Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States.

Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis (2018)
Journal Article
Chew-Graham, & Mamas. (2018). Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/jaha.118.008552

Abstract Background: There is growing evidence that sleep duration and quality may be associated with cardiovascular harm and mortality. Methods and Results: We conducted a systematic review, meta-analysis and spline analysis of prospective cohort st... Read More about Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis.