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The relationship of body mass index to percutaneous coronary intervention outcomes: Does the obesity paradox exist in contemporary PCI cohorts? Insights from the British Cardiovascular Intervention Society registry. (2017)
Journal Article
Mamas. (2017). The relationship of body mass index to percutaneous coronary intervention outcomes: Does the obesity paradox exist in contemporary PCI cohorts? Insights from the British Cardiovascular Intervention Society registry. JACC. Cardiovascular interventions, 1283-1292. https://doi.org/10.1016/j.jcin.2017.03.013

Objectives The aims of this study were to examine the relationship between body mass index (BMI) and clinical outcomes following percutaneous coronary intervention (PCI) and to determine the relevance of different clinical presentations requiring PC... Read More about The relationship of body mass index to percutaneous coronary intervention outcomes: Does the obesity paradox exist in contemporary PCI cohorts? Insights from the British Cardiovascular Intervention Society registry..

Transcatheter Aortic Valve Implantation With or Without Percutaneous Coronary Artery Revascularization Strategy: A Systematic Review and Meta-analysis (2017)
Journal Article
Mamas. (2017). Transcatheter Aortic Valve Implantation With or Without Percutaneous Coronary Artery Revascularization Strategy: A Systematic Review and Meta-analysis. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.117.005960

Background Recent recommendations suggest that in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation and coexistent significant coronary artery disease, the latter should be treated before the index procedure; ho... Read More about Transcatheter Aortic Valve Implantation With or Without Percutaneous Coronary Artery Revascularization Strategy: A Systematic Review and Meta-analysis.

Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus. (2017)
Journal Article
Mamas, M., & Rashid, M. (2017). Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus. Catheterization and Cardiovascular Interventions, 1195-1204. https://doi.org/10.1002/ccd.26882

OBJECTIVES: To assess the mortality in patients with diabetes mellitus (DM) following percutaneous coronary intervention (PCI) according to their insulin requirement and PCI setting (elective, urgent, and emergency). BACKGROUND: DM is a major risk fa... Read More about Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus..

Legacy Effect of Coronary Perforation Complicating Percutaneous Coronary Intervention for Chronic Total Occlusive Disease: An Analysis of 26 807 Cases From the British Cardiovascular Intervention Society Database (2017)
Journal Article
Kinnaird, T., Anderson, R., Ossei-Gerning, N., Cockburn, J., Sirker, A., Ludman, P., …Mamas, M. A. (2017). Legacy Effect of Coronary Perforation Complicating Percutaneous Coronary Intervention for Chronic Total Occlusive Disease: An Analysis of 26 807 Cases From the British Cardiovascular Intervention Society Database. Circulation: Cardiovascular Interventions, 10(5), https://doi.org/10.1161/circinterventions.116.004642

Do patients have a worse outcome with heart failure than cancer? A primary care based cohort study with 10-year follow-up in Scotland (2017)
Journal Article
Mamas. (2017). Do patients have a worse outcome with heart failure than cancer? A primary care based cohort study with 10-year follow-up in Scotland. European Journal of Heart Failure, 1095-1104. https://doi.org/10.1002/ejhf.822

Aims This study was designed to evaluate whether survival rates in patients with heart failure (HF) are better than those in patients with diagnoses of the four most common cancers in men and women, respectively, in a contemporary primary care cohor... Read More about Do patients have a worse outcome with heart failure than cancer? A primary care based cohort study with 10-year follow-up in Scotland.

Cerebral Embolic Protection Devices During Transcatheter Aortic Valve Implantation: Systematic Review and Meta-analysis (2017)
Journal Article
Mamas. (2017). Cerebral Embolic Protection Devices During Transcatheter Aortic Valve Implantation: Systematic Review and Meta-analysis. Stroke, 1306-1315. https://doi.org/10.1161/strokeaha.116.015915

Background and Purpose—Silent ischemic embolic lesions are common after transcatheter aortic valve implantation (TAVI). The use of embolic protection devices (EPD) may reduce the occurrence of these embolic lesions. Thus, a quantitative overview and... Read More about Cerebral Embolic Protection Devices During Transcatheter Aortic Valve Implantation: Systematic Review and Meta-analysis.

Aortic Stenosis and Non-Cardiac Surgery: A Systematic Review and Meta-Analysis (2017)
Journal Article
Rashid, & Mamas. (2017). Aortic Stenosis and Non-Cardiac Surgery: A Systematic Review and Meta-Analysis. International Journal of Cardiology, 145-153. https://doi.org/10.1016/j.ijcard.2017.04.037

Background Aortic stenosis (AS) poses a perioperative management dilemma to physicians looking after patients who require non-cardiac surgery. The objective of this review is to investigate mortality and adverse cardiovascular events in patients wit... Read More about Aortic Stenosis and Non-Cardiac Surgery: A Systematic Review and Meta-Analysis.

Choice of Stent for Percutaneous Coronary Intervention of Saphenous Vein Grafts. (2017)
Journal Article
Mamas. (2017). Choice of Stent for Percutaneous Coronary Intervention of Saphenous Vein Grafts. Circulation: Cardiovascular Interventions, https://doi.org/10.1161/CIRCINTERVENTIONS.116.004457

BACKGROUND: There are limited data on comparison of contemporary drug-eluting stent (DES) platforms, previous generation DES, and bare-metal stents (BMS) for percutaneous coronary intervention in saphenous vein grafts (SVG). We aimed to assess clinic... Read More about Choice of Stent for Percutaneous Coronary Intervention of Saphenous Vein Grafts..

Vascular access site and outcomes among 26,807 chronic total coronary occlusion angioplasty cases from the British Cardiovascular Interventions Society National database (2017)
Journal Article
Mamas, M., & Nolan, J. (2017). Vascular access site and outcomes among 26,807 chronic total coronary occlusion angioplasty cases from the British Cardiovascular Interventions Society National database. JACC: Cardiovascular Interventions, 635-644. https://doi.org/10.1016/j.jcin.2016.11.055

Objectives The aim of this study was to assess, using a national percutaneous coronary intervention (PCI) database, access-site choice and outcomes after chronic total occlusion (CTO) PCI. Background Given the influence of access site on outcome... Read More about Vascular access site and outcomes among 26,807 chronic total coronary occlusion angioplasty cases from the British Cardiovascular Interventions Society National database.

Change in angiogram-derived management strategy of patients with chest pain when some FFR data are available: How consistent is the effect? (2017)
Journal Article
Mamas. (2017). Change in angiogram-derived management strategy of patients with chest pain when some FFR data are available: How consistent is the effect?. Cardiovascular Revascularization Medicine, 320-327. https://doi.org/10.1016/j.carrev.2017.01.014

Background The assessment of patients presenting with angina using invasive angiography alone is imperfect. By contrast, fractional flow reserve (FFR) allows for assessment of lesion-specific ischemia, which is predictive of clinical outcome. A seri... Read More about Change in angiogram-derived management strategy of patients with chest pain when some FFR data are available: How consistent is the effect?.

Preeclampsia and Future Cardiovascular Health (2017)
Journal Article
Wu, P., Haththotuwa, R., Shing Kwok, C., Babu, A., Kotronias, R. A., Rushton, C., …Mamas, M. A. (2017). Preeclampsia and Future Cardiovascular Health. Circulation: Cardiovascular Quality and Outcomes, 10(2), https://doi.org/10.1161/circoutcomes.116.003497

Background— Preeclampsia is a pregnancy-specific disorder resulting in hypertension and multiorgan dysfunction. There is growing evidence that these effects persist after pregnancy. We aimed to systematically evaluate and quantify the evidence on th... Read More about Preeclampsia and Future Cardiovascular Health.

Pre-implantation Balloon Aortic Valvuloplasty and Clinical Outcomes Following Transcatheter Aortic Valve Implantation: A Propensity Score Analysis of the UK Registry (2017)
Journal Article
Mamas. (2017). Pre-implantation Balloon Aortic Valvuloplasty and Clinical Outcomes Following Transcatheter Aortic Valve Implantation: A Propensity Score Analysis of the UK Registry. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.116.004695

Background Aortic valve predilation with balloon aortic valvuloplasty (BAV) is recommended before transcatheter aortic valve implantation (TAVI), despite limited data around the requirement of this preprocedural step and the potential risks of embol... Read More about Pre-implantation Balloon Aortic Valvuloplasty and Clinical Outcomes Following Transcatheter Aortic Valve Implantation: A Propensity Score Analysis of the UK Registry.

Increased radial access is not associated with worse femoral outcomes for PCI in the United Kingdom (2017)
Journal Article
Hulme, W., Sperrin, M., Kontopantelis, E., Ratib, K., Ludman, P., Sirker, A., …Mamas, M. (2017). Increased radial access is not associated with worse femoral outcomes for PCI in the United Kingdom. Circulation: Cardiovascular Interventions, 10(2), 4279. https://doi.org/10.1161/CIRCINTERVENTIONS.116.004279

Background— The radial artery is increasingly adopted as the primary access site for cardiac catheterization because of patient preference, lower bleeding rates, cost effectiveness, and reduced risk of mortality in high-risk patient groups. Concerns... Read More about Increased radial access is not associated with worse femoral outcomes for PCI in the United Kingdom.

Variation in emergency percutaneous coronary intervention in ventilated patients in the UK: insights from a national database (2017)
Journal Article
Mamas. (2017). Variation in emergency percutaneous coronary intervention in ventilated patients in the UK: insights from a national database. Cardiovascular Revascularization Medicine, 250-254. https://doi.org/10.1016/j.carrev.2017.02.005

Aims Pre-procedural ventilation is a marker of high risk in PCI patients. Causes include out-of-hospital cardiac arrest (OHCA) and cardiogenic shock. OHCA occurs in approximately 60,000 patients in the UK per annum. No consensus exists regarding the... Read More about Variation in emergency percutaneous coronary intervention in ventilated patients in the UK: insights from a national database.

Impact of HIV on inpatient mortality and complications in stroke in Thailand; A National Database Study (2017)
Journal Article
Mamas. (2017). Impact of HIV on inpatient mortality and complications in stroke in Thailand; A National Database Study. Epidemiology and Infection, 1285-1291. https://doi.org/10.1017/S095026881600340X

The co-existence of stroke and HIV has increased in recent years, but the impact of HIV on post-stroke outcomes is poorly understood. We examined the impact of HIV on inpatient mortality, length of acute hospital stay and complications (pneumonia, re... Read More about Impact of HIV on inpatient mortality and complications in stroke in Thailand; A National Database Study.

5-Fr sheathless transradial cardiac catheterization using conventional catheters and balloon assisted tracking; a new approach to downsizing (2017)
Journal Article
Mamas, M. A., George, S., Ratib, K., Kwok, C. S., Elkhazin, A., Sandhu, K., …Nolan, J. (2017). 5-Fr sheathless transradial cardiac catheterization using conventional catheters and balloon assisted tracking; a new approach to downsizing. Cardiovascular Revascularization Medicine, 18(1), 28-32. https://doi.org/10.1016/j.carrev.2016.09.003

Response to letter by Dziewierz et al. on “Influence of access site choice for cardiac catheterization on risk of adverse neurological events: A systematic review and meta- analysis” (2017)
Journal Article
Mamas. (2017). Response to letter by Dziewierz et al. on “Influence of access site choice for cardiac catheterization on risk of adverse neurological events: A systematic review and meta- analysis”. American Heart Journal, 107-119. https://doi.org/10.1016/j.ahj.2017.01.013

Letter to the editor.

Endothelial progenitor cells: exploring the pleiotropic effects of statins (2017)
Journal Article
Mamas. (2017). Endothelial progenitor cells: exploring the pleiotropic effects of statins. World Journal of Cardiology, 1-13. https://doi.org/10.4330/wjc.v9.i1.1

Statins have become a cornerstone of risk modification for ischaemic heart disease patients. A number of studies have shown that they are effective and safe. However studies have observed an early benefit in terms of a reduction in recurrent infarct... Read More about Endothelial progenitor cells: exploring the pleiotropic effects of statins.

One-month global longitudinal strain identifies patients who will develop pacing-induced left ventricular dysfunction over time: the pacing and ventricular dysfunction (PAVD) study (2017)
Journal Article
Mamas. (2017). One-month global longitudinal strain identifies patients who will develop pacing-induced left ventricular dysfunction over time: the pacing and ventricular dysfunction (PAVD) study. PloS one, https://doi.org/10.1371/journal.pone.0162072

Background Predicting which individuals will have a decline in left ventricular (LV) function after pacemaker implantation remains an important challenge. We investigated whether LV global longitudinal strain (GLS), measured by 2D speckle tracking s... Read More about One-month global longitudinal strain identifies patients who will develop pacing-induced left ventricular dysfunction over time: the pacing and ventricular dysfunction (PAVD) study.